HOME >> BIOLOGY >> NEWS
Methamphetamine drastically increases virus' ability to replicate in brain tissue

COLUMBUS, Ohio - A controversial research study here has found that exposing cells infected with feline immunodeficiency virus - a surrogate for HIV - to methamphetamine increases those cells' ability to replicate the deadly virus as much as 15-fold.

The finding, if confirmed by ongoing animal studies, could answer important questions about how lentiviruses such as FIV and HIV can gain a foothold in the brain. That knowledge is vital in slowing or lessening the dementia that often accompanies AIDS and similar diseases.

Ohio State University researchers reported this finding in a paper to be published in the next issue of the Journal of NeuroVirology.

The paper also reports that before a nerve cell can become infected with the virus, it must be associated with a specific type of lymphocyte, or immune cell. Lastly, the researchers discovered that once the virus infects the cells, it mutates into a form that no longer needs this immune-cell association to reproduce.

"We found that after about two weeks of chronic methamphetamine exposure, the ability of these infected cell lines to mass-produce virus increases dramatically," explained Michael Podell, a professor of veterinary clinical sciences and neu
'"/>

Contact: Earle Holland
Holland.8@osu.edu
614-292-8384
Ohio State University
5-Jun-2002


Page: 1 2 3 4

Related biology news :

1. OHSU Scientists Discover Mice Lacking Dopamine Receptor Are Supersensitive To Alcohol, Cocaine And Methamphetamine
2. Combination drug therapy drastically reduces multiple coronary heart disease risk factors
3. Lab scientists develop DNA signatures for salmonella strain that are expected to drastically speed detection
4. USC study links historical increases in life span to lower childhood exposure to infection
5. Moderate alcohol consumption increases plasma levels of a protective hormone
6. Protease-inhibitor cocktail protects, increases anti-microbial action of promising new peptide
7. Breast self examination increases womens concerns but has no effect on mortality
8. Educational program increases some safety behaviors for older drivers
9. Placental malaria increases mother-to-child HIV transmission
10. NIEHS-funded researchers find low-level ozone increases respiratory risk of asthmatic children
11. Northwesterns Cancer Genetics Program pinpoints gene that increases cancer risk by 26 percent

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, a global ... of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga prefecture of ... located in Kakegawa, the new 60,000-square-foot facility will provide customers with flexible clinical ...
(Date:6/25/2020)... ... June 24, 2020 , ... eClinical Solutions ... data services that accelerate drug development, is collaborating with Karyopharm Therapeutics (Nasdaq: ... hospitalized patients with severe COVID-19. This is the first study of an XPO1 ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... pleased to announce the next event in a series of TOPIQ webinars, which ... TOPIQ series of webinars was developed in response to social distancing measures that ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... MIAMI (PRWEB) , ... July 29, 2020 , ... ... nearly 200 of the top radiation centers in 16 countries, has reached its ... years, SDX® is now in routine use at top universities including University of ...
(Date:7/18/2020)... ... July 16, 2020 , ... ... in the early detection and prevention of high-burden diseases, and Centric Consulting, a ... and healthcare organizations to utilize existing data in order to identify and prioritize ...
(Date:7/10/2020)... ... July 09, 2020 , ... Sentien Biotechnologies, Inc., a ... of Allen R. Nissenson, M.D., F.A.C.P., as its Chief Medical Officer. Dr. ... lead product, SBI-101. Dr. Nissenson serves as an Emeritus Professor of Medicine ...
(Date:7/1/2020)... ... June 30, 2020 , ... ... that the launch of a new clinical diagnostics immuno-oncology service, TissueInsight ... microenvironment (TME). , “Flagship’s TissueInsight is a service that aids pathologists, oncologists, ...
Breaking Biology Technology:
Cached News: