HOME >> BIOLOGY >> NEWS
Models help estimate children's exposure to toxins

For almost 10 years, Stanford's Jim Leckie and his students have been successfully collecting immense amounts of data, writing original software and building sophisticated statistical models - all to begin to measure how children are exposed to chemicals in their environments. But Leckie, the C. L. Peck, Class of 1906 Professor in the School of Engineering, may have achieved his greatest success when he decided to study children in the first place.

''When we began this work, most of the regulations were based on studies of adult white men - the healthiest segment of the population,'' Leckie will tell an audience Feb. 16 at a symposium on toxic substances in the environment at the annual meeting of the American Association for the Advancement of Science.

The foundation of Leckie's research is careful observation of the activities of normal, healthy children in everyday environments. His video cameras have captured hours of mundane activity in the homes of middle-class suburbanites and migrant farm workers.

It is not yet clear whether trace amounts of synthetic chemicals, increasingly present in the environment, pose a risk to human health. But it makes sense to begin to consider the issue by studying children, the most vulnerable segment of the population.

Compared to adults, young children have cell walls that are more permeable to environmental toxins. Babies are born with incomplete liver and kidney functions; the ability to detoxify chemicals matures with age. Children also have higher surface-to-volume ratios. So if a child and an adult are exposed to the same environment and absorb toxins through the skin, the child will receive a greater relative dose.

Leckie has used the hours of footage to build realistic models of how children might ingest or otherwise become exposed to substances, including toxins such as lead and pesticides, which may be present in their immediate environments in small amounts. The development of th
'"/>

Contact: Dawn Levy
dawnlevy@stanford.edu
650-725-1944
Stanford University
16-Feb-2004


Page: 1 2 3 4

Related biology news :

1. Applied Mathematical Models in Human Physiology
2. Models show gene flow from crops threatens wild plants
3. U.S. - FSU Partnering Models
4. Duke Geologist Decries Using Engineering Models To Predict Natural Phenomena
5. Models Assess Remedial Actions On Abandoned Mine Lands In Colorado
6. Computer Models Find Cost-Effective Solutions For Species Preservation
7. Global Change: Will Some Plant Species Be Left Behind? Studies Of EcosystemDynamics Make Wide Use Of Computer Models
8. Induced Mutant Mouse Models Of Lipoprotein Disorders And Atherosclerosis
9. NCAR Scientist Models Earths Climate and Vegetation Patterns At Last Glacial Peak
10. Cancer health risk significantly underestimated by EPAs ambient model estimates
11. Improved estimates of population extinction risk (Harding and McNamara)

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/3/2016)... Das DOTM (Department ... hat ein 44 Millionen $-Projekt ... einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an Decatur ... Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale Anbieter ... aber Decatur wurde als konformste und innovativste ...
(Date:5/24/2016)... 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology to ... display is the latest premium product recently added to the range of products distributed ... ... ... Imaging- LCD Medical Display- Ampronix News ...
(Date:5/3/2016)... VILNIUS, Lithuania , May 3, 2016 /PRNewswire/ ... today released the MegaMatcher Automated Biometric Identification ... deployment of large-scale multi-biometric projects. MegaMatcher ABIS can ... and accuracy using any combination of fingerprint, face ... of MegaMatcher SDK and MegaMatcher ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...  Sequenom, Inc. (NASDAQ: SQNM ), a ... the development of innovative products and services, announced today ... States denied its petition to review decisions ... U.S. Patent No. 6,258,540 (",540 Patent") are not patent ... Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories decision.  ...
(Date:6/27/2016)...  Liquid Biotech USA , ... Sponsored Research Agreement with The University of Pennsylvania ... cancer patients.  The funding will be used to ... clinical outcomes in cancer patients undergoing a variety ... employed to support the design of a therapeutic, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita ... miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the subject of ... now. , Diagnostic biomarkers are signposts in the blood, lung fluid or tissue ...
(Date:6/23/2016)... -- A person commits a crime, and the detective uses ... criminal down. An outbreak of foodborne illness makes ... uses DNA evidence to track down the bacteria that caused ... not. The FDA has increasingly used a complex, cutting-edge technology ... Put as simply as possible, whole genome sequencing is a ...
Breaking Biology Technology:
Cached News: