HOME >> BIOLOGY >> NEWS
Mouse brain stem cells capable of converting into blood vessel cells

Adult stem cells in the brains of mice possess a broader differentiation potential than previously thought and may be capable of developing into other cell types including those involved in the formation of new blood vessels, according to a new study supported by the National Institute on Aging (NIA), a part of the National Institutes of Health. The finding could help resolve a critical question about these promising, but still mystifying cells.

The report by Fred H. Gage, Ph.D., and colleagues at the Salk Institute in La Jolla, CA, and Kumamoto University in Japan, appears in the July 15, 2004, issue of Nature.

Adult stem cells in the brain were proposed to be restricted to the generation of neurons and cells, such as glial cells, that support neuron function. Experiments over the past several years have raised the possibility that stem cells from the brain may be able to give rise to additional cell types, a phenomenon known as plasticity. But recent findings have challenged this theory, suggesting that many of these stem cells merely merge or "fuse" with an existing cell within a tissue forming a hybrid that takes on the pre-existing cell's functions.

"Resolving this issue is important because fused cells may have a different therapeutic potential than stem cells that differentiate into new cells, says Bradley C. Wise, Ph.D., of the NIA's Neuroscience and Neuropsychology of Aging Program. "While this new finding doesn't fully answer this vital question, it keeps open the possibility that adult stem cells from different organs one day may be harnessed to help prevent and treat neurological disorders."

In their experiments, Gage and his colleagues grew mouse brain stem cells, which form neurons and glial cells, in the same culture dishes with human endothelial cells, which form the lining of blood vessels. Over time, about 6 percent of the mouse neural stem cells began to show signs that they had developed into cells similar to endot
'"/>

Contact: Doug Dollemore
dollemod@nia.nih.gov
301-496-1752
NIH/National Institute on Aging
14-Jul-2004


Page: 1 2

Related biology news :

1. Half-million dollar landmark achieved for the Methuselah Mouse Prize
2. Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
3. Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
4. Mouse embryonic germ cells and male gametes created in the lab
5. Mouse, stripped of a key gene, resists diabetes
6. Mouse model of schizophrenia could speed identification of new antipsychotic drugs
7. Mouse study identifies protective mechanism against alcohol-induced embryo toxicity
8. Mouse model offers new explanation for kidney disease and failure
9. Mouse study suggests mammoth evolutionary change
10. Mouse genetic model for spongiform brain diseases
11. Mouse model links alcohol intake to marijuana-like brain compounds

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mouse brain stem cells capable converting into blood vessel cells

(Date:3/23/2015)... Mar. 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... the growing mobile commerce market, announces its biometric payment technology, ... on CNBC television starting March 30 th . ... in New York markets. ... are excited about our new ad campaign following the recent ...
(Date:3/20/2015)... and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has announced the ... Report" report to their offering. This report ... The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period ...
(Date:3/20/2015)... DUBLIN , Mar. 19, 2015 Research and Markets ... the "Iris Biometrics - Global Strategic Business Report" ... worldwide markets for Iris Biometrics in US$ Thousands. The report ... , Japan , Europe ... East , and Latin America . ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5
(Date:4/1/2015)... April 01, 2015 Shimadzu Corporation ... Nexera Unified Chromatography system (Nexera UC) received the ... Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon) ... and 12th. , The Pittcon Editors’ Awards ... for the first time based on votes by ...
(Date:4/1/2015)... April 1, 2015  ValGenesis Inc., the market leader ... that it has completed its Service Organization Controls 2 ... (AICPA, Professional Standards) for the period of January 1 ... ... The SOC 2 examination is ...
(Date:4/1/2015)... Proove Biosciences , a commercial ... two scientific posters at the Annual Clinical Genetics Meeting ... event was hosted at the Salt Palace Convention Center ... genetic and genomic professionals on breakthrough advances in clinical ... on the Role of DAT1 in Risk of Insomnia ...
(Date:4/1/2015)... 2015  Organovo Holdings, Inc. (NYSE MKT: ONVO) ... breakthrough 3D bioprinting technology, presented data on the ... 2015 Experimental Biology conference in Boston, ... an ideal extension of Organovo,s capabilities to 3D ... in pharmaceutical research," said Keith Murphy , ...
Breaking Biology Technology:Shimadzu Nexera UC Recognized at Pittcon 2015 with Editors’ Gold Award 2ValGenesis Inc. Successfully Completes Service Organization Controls 2 (SOC 2) Report under AT Section 101 2ValGenesis Inc. Successfully Completes Service Organization Controls 2 (SOC 2) Report under AT Section 101 3Proove Biosciences Presents Research Studies at Annual Clinical Genetics Meeting 2015 2Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 2Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 3Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue 4
Cached News: