HOME >> BIOLOGY >> NEWS
Mouse embryo hints at how mammalian body forms

, while those opposite the polar body became located at the other end.

The fact that the cells projected in a uniform and consistent way suggests, suggests, the researchers say, that the early blastocyst's axis of bilateral symmetry predicts the spatial patterning of the post-implantation embryo.

"This is the first evidence that the polarity at post-implantation stages, when the body plan is established, can be traced back to events before implantation," says Zernicka-Goetz."

The fact that the fertilized egg of the mouse - and probably other mammals -- share this principle of early organization with other organisms offers fuel for future studies.

"Knowing what we now do, the mouse embryo model will be that much more effective for these studies, and the other models studied may be informative of things we hadn't anticipated; in other words, the finding may make frogs more germane to us," says Zernicka-Goetz.

Researchers have already identified molecular systems in frogs that are strongly implicated in inducing gastrulation, and these systems could play an important role in animals with backbones, including mammals, the researchers say. It is possible that the as-yet-unidentified molecular mechanisms of body formation in the mouse embryo could be similar to those seen in the frog.

The new results, the researchers say, could also prove useful for gaining control over embryonic stem cells. "Looking at what's going on molecularly in embryos at the time of gastrulation could provide insight into the molecular forces underlying embryonic stem cell differentiation," says Pedersen. "This could provide the missing clue as to how to control the differentiation of stem cells in vitro."

The most likely way to get embryonic stem cells to differentiate into specific cell lines, he surmises, is to do what the embryo does - first make them differentiate into endoderm, mesoderm and ectoderm. Once this has been achiev
'"/>

Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
19-Dec-1999


Page: 1 2 3 4 5

Related biology news :

1. Half-million dollar landmark achieved for the Methuselah Mouse Prize
2. Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
3. Mouse brain stem cells capable of converting into blood vessel cells
4. Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
5. Mouse embryonic germ cells and male gametes created in the lab
6. Mouse, stripped of a key gene, resists diabetes
7. Mouse model of schizophrenia could speed identification of new antipsychotic drugs
8. Mouse study identifies protective mechanism against alcohol-induced embryo toxicity
9. Mouse model offers new explanation for kidney disease and failure
10. Mouse study suggests mammoth evolutionary change
11. Mouse genetic model for spongiform brain diseases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... , April 13, 2017 According to a ... Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment ... the IAM Market is expected to grow from USD 14.30 Billion in ... Rate (CAGR) of 17.3%. ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 11, 2017 Research and Markets has announced ... report to their offering. ... global eye tracking market to grow at a CAGR of 30.37% ... Tracking Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
(Date:4/11/2017)... -- NXT-ID, Inc. (NASDAQ:   NXTD ) ("NXT-ID" ... of independent Directors Mr. Robin D. Richards and ... furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive Officer ... guidance and benefiting from their considerable expertise as we move ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 22, 2017 , ... ... row in the Aragon Research Globe™ for Corporate Learning, 2017. , Aragon Research ... and market demand, and effectively perform against those strategies. NetDimensions’ ranking as a ...
(Date:5/23/2017)... , ... May 23, 2017 , ... Vortex Biosciences ... “Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology ” in ... of a collaboration with Dr. Dino Di Carlo and Dr. Matthew Rettig at the ...
(Date:5/23/2017)... ... 23, 2017 , ... Kathy Goin is joining myClin ... brings years of expertise in establishing and leading clinical operations at Sponsors including ... occupational therapist, through a variety of leadership roles in Clinical Operations, to her ...
(Date:5/23/2017)... ... May 23, 2017 , ... Cambridge Semantics , the leading ... year’s Bio-IT World Conference and Expo in Boston May 23-25 with a ... The Anzo Smart Data Lake is also a finalist for the Best of ...
Breaking Biology Technology:
Cached News: