Mouse study suggests mammoth evolutionary change

, some 45 miles northwest of Chicago. That discovery prompted Pergams to get all the museum specimens that were collected in Illinois' Cook and Lake counties.

The researchers used DNA taken not from the nucleus, but from mitochondria, the power plants of the cell. Each cell contains many mitochondria, but only one nucleus.

"If you are working with very degraded, ancient DNA like that from museum skins, you are way ahead using this DNA with lots of copies," said Pergams. Mitochondrial DNA evolves much more rapidly than nuclear DNA, he said, though this evolution was previously thought only to occur over thousands of years.

"We did not expect to find the rapid, consistent and directional change that we did find," he said.

While evidence of such fast change has been cited in studies of fruit flies, this is the first reported study to document such quick evolution in a mammal.

What may account for this change?

"We think it likely that the new gene sequence was either unconditionally advantageous, or that it was advantageous relative to environmental changes caused by humans," Pergams said.

"Settlers may have brought in mice with the favorable gene that were able to out-compete mice with the native variant. A less likely possibility is that mice with these new gene sequences were already present, and that dramatic changes that humans caused in the environment allowed the new gene sequence to be selectively advantageous."

Since all the mice studied were caught in forest preserves and parks, Pergams and Nyberg consider the second alternative unlikely. Future studies should reveal if the favorable gene is in older mouse specimens held by museums in other parts of the country.

In any event, Pergams thinks this research may have broad implications.

"It suggests that humans are a likely cause of such rapid evolution," Pergams said, "and that much of current phylogenetic and phylogeographi

Contact: Paul Francuch
University of Illinois at Chicago

Page: 1 2 3

Related biology news :

1. Half-million dollar landmark achieved for the Methuselah Mouse Prize
2. Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
3. Mouse brain stem cells capable of converting into blood vessel cells
4. Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
5. Mouse embryonic germ cells and male gametes created in the lab
6. Mouse, stripped of a key gene, resists diabetes
7. Mouse model of schizophrenia could speed identification of new antipsychotic drugs
8. Mouse study identifies protective mechanism against alcohol-induced embryo toxicity
9. Mouse model offers new explanation for kidney disease and failure
10. Mouse genetic model for spongiform brain diseases
11. Mouse model links alcohol intake to marijuana-like brain compounds

Post Your Comments:

(Date:10/29/2015)... 29, 2015 Daon, a global leader in ... released a new version of its IdentityX Platform ... North America have already installed IdentityX v4.0 ... a FIDO UAF certified server component as ... activate FIDO features. These customers include some of the ...
(Date:10/27/2015)... 2015 In the present market scenario, security ... various industry verticals such as banking, healthcare, defense, electronic ... demand for secure & simplified access control and growing ... hacking of bank accounts, misuse of users, , and ... PC,s, laptops, and smartphones are expected to provide potential ...
(Date:10/26/2015)... 26, 2015  Delta ID Inc., a company focused ... and PC devices, announced its ActiveIRIS® technology powers the ... F-02H launched by NTT DOCOMO, INC in ... second smartphone to include iris recognition technology, after a ... F-04G in May 2015, world,s first smartphone to have ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... --> --> ... by Transparency Market Research, the global non-invasive prenatal testing ... 17.5% during the period between 2014 and 2022. The ... Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 ... to reach a valuation of US$2.38 bn by 2022. ...
(Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris ... today that the remaining 11,000 post-share consolidation (or ... Warrants (the "Series B Warrants") subject to the ... on November 23, 2015, which will result in ... giving effect to the issuance of such shares, ...
(Date:11/24/2015)... Switzerland (PRWEB) , ... November 24, 2015 , ... ... plant and the environment are paramount. Insertion points for in-line sensors can represent ... has developed the InTrac 781/784 series of retractable sensor housings , which ...
(Date:11/24/2015)... ... November 24, 2015 , ... Creation Technologies ... being named to Deloitte's 2015 Technology Fast 500 list of the fastest growing ... a FDA-cleared, Class II medical device that speeds up orthodontic tooth movement by ...
Breaking Biology Technology:
Cached News: