HOME >> BIOLOGY >> NEWS
Mouse study suggests mammoth evolutionary change

, some 45 miles northwest of Chicago. That discovery prompted Pergams to get all the museum specimens that were collected in Illinois' Cook and Lake counties.

The researchers used DNA taken not from the nucleus, but from mitochondria, the power plants of the cell. Each cell contains many mitochondria, but only one nucleus.

"If you are working with very degraded, ancient DNA like that from museum skins, you are way ahead using this DNA with lots of copies," said Pergams. Mitochondrial DNA evolves much more rapidly than nuclear DNA, he said, though this evolution was previously thought only to occur over thousands of years.

"We did not expect to find the rapid, consistent and directional change that we did find," he said.

While evidence of such fast change has been cited in studies of fruit flies, this is the first reported study to document such quick evolution in a mammal.

What may account for this change?

"We think it likely that the new gene sequence was either unconditionally advantageous, or that it was advantageous relative to environmental changes caused by humans," Pergams said.

"Settlers may have brought in mice with the favorable gene that were able to out-compete mice with the native variant. A less likely possibility is that mice with these new gene sequences were already present, and that dramatic changes that humans caused in the environment allowed the new gene sequence to be selectively advantageous."

Since all the mice studied were caught in forest preserves and parks, Pergams and Nyberg consider the second alternative unlikely. Future studies should reveal if the favorable gene is in older mouse specimens held by museums in other parts of the country.

In any event, Pergams thinks this research may have broad implications.

"It suggests that humans are a likely cause of such rapid evolution," Pergams said, "and that much of current phylogenetic and phylogeographi
'"/>

Contact: Paul Francuch
francuch@uic.edu
312-996-3457
University of Illinois at Chicago
21-May-2003


Page: 1 2 3

Related biology news :

1. Half-million dollar landmark achieved for the Methuselah Mouse Prize
2. Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
3. Mouse brain stem cells capable of converting into blood vessel cells
4. Mouse study yields clue to why liver is less prone to rejection, say Pitt researchers
5. Mouse embryonic germ cells and male gametes created in the lab
6. Mouse, stripped of a key gene, resists diabetes
7. Mouse model of schizophrenia could speed identification of new antipsychotic drugs
8. Mouse study identifies protective mechanism against alcohol-induced embryo toxicity
9. Mouse model offers new explanation for kidney disease and failure
10. Mouse genetic model for spongiform brain diseases
11. Mouse model links alcohol intake to marijuana-like brain compounds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/6/2017)... , March 6, 2017 Mintigo ... technology, today announced Predictive Sales Coach TM , ... actionable sales intelligence into Salesforce. This unique AI ... their sales organizations with deep knowledge of their ... for intelligent engagement. Predictive Sales Coach extends Mintigo,s ...
(Date:3/2/2017)... , March 2, 2017 Australian stem cell ... (ASX: CYP), has signed an agreement with the Monash ... Monash Biomedicine Discovery Institute and Department of Pharmacology at ... a further preclinical study to support the use of ... asthma.  Asthma is a chronic, long ...
(Date:2/28/2017)... Spanien, 27. Februar 2017  EyeLock LLC, ein marktführendes ... seine erstklassige biometrische Lösung zur Iris-Erkennung auf ... X16 LTE auf dem Mobile World Congress ... Qualcomm-Stand in Halle 3, Stand 3E10, vorstellen. ... Sicherheitsplattform Qualcomm Haven™ – eine Kombination aus ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... Biotech Ltd. ("Sinovac" or the "Company") (NASDAQ: SVA), a leading provider ... that its board of directors has amended its shareholder rights plan. The ... 2017 to March 27, 2018. The amendment was not in response to ... ... Ltd. is a China -based biopharmaceutical company that ...
(Date:3/24/2017)... 24, 2017 Agenus Inc. (NASDAQ: AGEN), an ... and cancer vaccines, today announced participation at the following ... William Blair and Maidstone Life Sciences conference "Cancer Immunotherapy ... New York, NY . Agenus will ... at 9:40 am: Robert B. Stein , M.D., ...
(Date:3/23/2017)... 2017 Research and Markets has announced ... report to their offering. ... The Global Market for Bioproducts Should ... at a CAGR of 8.9%, This research ... into seven major product segments: bio-derived chemicals, biofuels, pharmaceuticals (biodrugs ...
(Date:3/23/2017)... March 23, 2017  GlobeImmune, Inc. today announced it ... sale of 12,835,490 shares of its common stock to ... companies. In connection with the sale of its common stock, ... and issue to GlobeImmune 200,000 shares, an estimated $2.0 ... "We are pleased to enter into this strategic ...
Breaking Biology Technology:
Cached News: