HOME >> BIOLOGY >> NEWS
Mouth microbes may help shape immune system, says Stanford research team

STANFORD, Calif. - The immune system may be shaped by some of the very agents it exists to fight, according to research by David Relman, MD, associate professor of medicine and of microbiology and immunology at Stanford University School of Medicine.

"Microbes not only provide functions that promote health, but may actually guide the stages of our own immune system development," said Relman. "It seems reasonable to propose that only until we have an idea of the make-up and variability of the microbial ecosystems living within us do we begin to get an idea of the mechanisms underlying the functions they perform, such as immune system maturation and defense against pathogens."

Relman will present an overview of his lab's work on this subject, along with some new findings Feb. 16 as part of the "Innate Immunity and Oral Health" program at the annual meeting of the American Association for the Advancement of Science in Seattle.

The mouth provides a thriving community of microbes and a unique field in which to study how these tiny creatures interact with their hosts. Relman's group has concentrated efforts on the subgingival crevice - the deep gap between the gums and teeth - in their search for microbes. Even though almost 500 bacterial strains or species have been identified in this oral pocket, Relman believes there remains a substantial amount to be learned about their behavior and response to perturbation, such as brushing and flossing, and environmental insults such as being attacked by the immune system.

Some of the most basic kinds of questions remain unanswered in the microbial world, said Relman. While there is a general consensus that bacteria play a role in causing gum disease, no single microbe has been implicated as the culprit. "The details on how oral microbes cause disease is probably not a simple story," said Relman. "One agent does not equal one disease. There are complex interactions between members of the oral flora
'"/>

Contact: Mitzi Baker
mitzibaker@stanford.edu
650-725-2106
Stanford University Medical Center
16-Feb-2004


Page: 1 2

Related biology news :

1. Foot-and-Mouth disease: Can research offer solutions? Science feature examines prevention and detection efforts
2. First Study To Take Bacteria Directly From Patients Mouths Further Supports Possible Link Between Gum And Heart Disease
3. Finding the hole in the defenses of cavity-creating microbes
4. Figs may inhibit growth and survival of harmful microbes in food
5. Discovery of tiny microbes in ancient Greenland glacier may define limits for life on Earth
6. Small, cold, & hungry: Ultra-small microbes from 120,000-year-old glacier ice sample
7. Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
8. Researchers discover 1.2 million new genes in Sargasso Sea microbes
9. Fuel-cell microbes double duty: treat water, make energy
10. Navy enlists microbes to cut costs
11. Researchers probe how microbes speed up acid production at mining sites

Post Your Comments:
(Date:12/22/2014)... Holiday Season may be the brightest ever for the ... long anticipated floodgates for consumer biometrics may finally be ... tablets, and wearable mobile devices that incorporate biometrics will ... nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal genetics company, ... differences in genetic ancestry of individuals from across ... arrived more than four hundred years ago, the ... for peoples from different continents. This study illuminates how American ...
(Date:12/17/2014)... Dec. 15, 2014 The Defense Logistics Agency is ... and prevent counterfeit microcircuits from entering into its supply ... in-house microcircuit anti-counterfeit initiative dubbed DNA marking. The capability ... their reliability throughout the supply chain. The new quality ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
(Date:1/23/2015)... Biofertilizers stimulate microbial activities in soil. ... phosphorous through the activities in the soil or in ... to the stress on reducing environmental pollution and on ... defines and segments the bio fertilizers market with analysis ...
(Date:1/22/2015)... Shimadzu Scientific Instruments today announces ... spectrophotometer. Offering wavelength scanning from 190 to 1,100 ... applications in a variety of industries, including environmental, ... UV-1280 enables intuitive operation, while the enhanced validation, ...
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart data solutions ... a record-breaking year across the board for the company. ... Platform and our Smart Data solutions, our customers were able ... led to record growth for the company in 2014,” said ...
(Date:1/22/2015)... January 22, 2015 Pipette.com has added ... to their comprehensive portfolio of Eppendorf products. , The ... purchase a Centrifuge 5424/5424 R and receive the following:, ... Eppendorf Research plus or Eppendorf Reference 2 , ...
Breaking Biology Technology:Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 2Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 3Biofertilizers Market Expected to Reach $1,649.7 Million by 2019 - New Report By MarketsandMarkets 4Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Cambridge Semantics Announces Record Results for 2014 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
Cached News: