HOME >> BIOLOGY >> NEWS
Mouth microbes may help shape immune system, says Stanford research team

STANFORD, Calif. - The immune system may be shaped by some of the very agents it exists to fight, according to research by David Relman, MD, associate professor of medicine and of microbiology and immunology at Stanford University School of Medicine.

"Microbes not only provide functions that promote health, but may actually guide the stages of our own immune system development," said Relman. "It seems reasonable to propose that only until we have an idea of the make-up and variability of the microbial ecosystems living within us do we begin to get an idea of the mechanisms underlying the functions they perform, such as immune system maturation and defense against pathogens."

Relman will present an overview of his lab's work on this subject, along with some new findings Feb. 16 as part of the "Innate Immunity and Oral Health" program at the annual meeting of the American Association for the Advancement of Science in Seattle.

The mouth provides a thriving community of microbes and a unique field in which to study how these tiny creatures interact with their hosts. Relman's group has concentrated efforts on the subgingival crevice - the deep gap between the gums and teeth - in their search for microbes. Even though almost 500 bacterial strains or species have been identified in this oral pocket, Relman believes there remains a substantial amount to be learned about their behavior and response to perturbation, such as brushing and flossing, and environmental insults such as being attacked by the immune system.

Some of the most basic kinds of questions remain unanswered in the microbial world, said Relman. While there is a general consensus that bacteria play a role in causing gum disease, no single microbe has been implicated as the culprit. "The details on how oral microbes cause disease is probably not a simple story," said Relman. "One agent does not equal one disease. There are complex interactions between members of the oral flora
'"/>

Contact: Mitzi Baker
mitzibaker@stanford.edu
650-725-2106
Stanford University Medical Center
16-Feb-2004


Page: 1 2

Related biology news :

1. Foot-and-Mouth disease: Can research offer solutions? Science feature examines prevention and detection efforts
2. First Study To Take Bacteria Directly From Patients Mouths Further Supports Possible Link Between Gum And Heart Disease
3. Finding the hole in the defenses of cavity-creating microbes
4. Figs may inhibit growth and survival of harmful microbes in food
5. Discovery of tiny microbes in ancient Greenland glacier may define limits for life on Earth
6. Small, cold, & hungry: Ultra-small microbes from 120,000-year-old glacier ice sample
7. Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
8. Researchers discover 1.2 million new genes in Sargasso Sea microbes
9. Fuel-cell microbes double duty: treat water, make energy
10. Navy enlists microbes to cut costs
11. Researchers probe how microbes speed up acid production at mining sites

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... anticipated to expand at a CAGR of 25.76% during ... diseases is the primary factor for the growth of ... report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global ... product, technology, application, and geography. The stem cell market ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
(Date:3/24/2017)... DUBLIN , Mar 24, 2017 Research ... Vehicle Access System Market Analysis & Trends - Industry Forecast to ... ... poised to grow at a CAGR of around 15.1% over the ... This industry report analyzes the market estimates and forecasts for ...
Breaking Biology News(10 mins):
(Date:7/17/2017)... Salt Lake City, Utah (PRWEB) , ... July ... ... the “Company”), a molecular diagnostics company that has developed and intends both to ... offering and started trading on the NASDAQ Capital Market. , Headquartered in Sandy, ...
(Date:7/16/2017)... PARSIPPANY, N.J. (PRWEB) , ... July 16, 2017 ... ... products, laboratory equipment and analytical instruments announced the launch of its new line ... shakers are ideal for applications that require CO2 and humidity for optimal cell ...
(Date:7/14/2017)... AZ (PRWEB) , ... July 13, 2017 , ... Dr. ... for ailing dental implants into his practice, Mondlick Perio, in the Phoenix area. ... with the world's first and only FDA cleared laser treatment to re-grow bone and ...
(Date:7/13/2017)... (PRWEB) , ... July 13, 2017 , ... Thousands of ... and August for the National Aeromodeling Championships (Nats). Pilots come to Muncie to compete ... to earn spots on US teams that participate in world championships. , RC Pylon ...
Breaking Biology Technology:
Cached News: