HOME >> BIOLOGY >> NEWS
Mouth microbes may help shape immune system, says Stanford research team

STANFORD, Calif. - The immune system may be shaped by some of the very agents it exists to fight, according to research by David Relman, MD, associate professor of medicine and of microbiology and immunology at Stanford University School of Medicine.

"Microbes not only provide functions that promote health, but may actually guide the stages of our own immune system development," said Relman. "It seems reasonable to propose that only until we have an idea of the make-up and variability of the microbial ecosystems living within us do we begin to get an idea of the mechanisms underlying the functions they perform, such as immune system maturation and defense against pathogens."

Relman will present an overview of his lab's work on this subject, along with some new findings Feb. 16 as part of the "Innate Immunity and Oral Health" program at the annual meeting of the American Association for the Advancement of Science in Seattle.

The mouth provides a thriving community of microbes and a unique field in which to study how these tiny creatures interact with their hosts. Relman's group has concentrated efforts on the subgingival crevice - the deep gap between the gums and teeth - in their search for microbes. Even though almost 500 bacterial strains or species have been identified in this oral pocket, Relman believes there remains a substantial amount to be learned about their behavior and response to perturbation, such as brushing and flossing, and environmental insults such as being attacked by the immune system.

Some of the most basic kinds of questions remain unanswered in the microbial world, said Relman. While there is a general consensus that bacteria play a role in causing gum disease, no single microbe has been implicated as the culprit. "The details on how oral microbes cause disease is probably not a simple story," said Relman. "One agent does not equal one disease. There are complex interactions between members of the oral flora
'"/>

Contact: Mitzi Baker
mitzibaker@stanford.edu
650-725-2106
Stanford University Medical Center
16-Feb-2004


Page: 1 2

Related biology news :

1. Foot-and-Mouth disease: Can research offer solutions? Science feature examines prevention and detection efforts
2. First Study To Take Bacteria Directly From Patients Mouths Further Supports Possible Link Between Gum And Heart Disease
3. Finding the hole in the defenses of cavity-creating microbes
4. Figs may inhibit growth and survival of harmful microbes in food
5. Discovery of tiny microbes in ancient Greenland glacier may define limits for life on Earth
6. Small, cold, & hungry: Ultra-small microbes from 120,000-year-old glacier ice sample
7. Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
8. Researchers discover 1.2 million new genes in Sargasso Sea microbes
9. Fuel-cell microbes double duty: treat water, make energy
10. Navy enlists microbes to cut costs
11. Researchers probe how microbes speed up acid production at mining sites

Post Your Comments:
(Date:8/28/2014)... . Cars, planes ... of sophisticated assembly lines. Mobile assembly carriers, on to which ... assembly lines. In the case of a car body, the ... a precise spatial and chronological sequence, resulting in a complete ... of such an assembly line at molecular level has been ...
(Date:8/28/2014)... Log exports from Washington, Oregon, northern California, and Alaska ... second quarter of 2014, an increase of more than ... the U.S. Forest Service,s Pacific Northwest Research Station reported ... decreased by 4 percent to 247 million board feet. ... by more than 5 percent to $390 million in ...
(Date:8/28/2014)... will be fully saturated with pests by the middle ... a new study led by the University of Exeter. ... found in around half the countries that grow their ... rate, scientists fear that a significant proportion of global ... next 30 years. , Crop pests include fungi, bacteria, ...
Breaking Biology News(10 mins):Nanoscale assembly line 2Nanoscale assembly line 3West coast log exports up, lumber exports down in second quarter of 2014 2New study charts the global invasion of crop pests 2
(Date:8/29/2014)... NY (PRWEB) August 29, 2014 Local ... Hills Veterinary Hospital are seeking candidates to participate in ... with osteoarthritis. The ultimate goal of this study ... stem cells into one or two arthritically affected joints ... joints. , Candidates for the current investigational study ...
(Date:8/29/2014)... A major challenge before new biotechnology ... realm of Boston-Cambridge, is gaining visibility that can lead ... the Director of Boston’s Adult Stem Cell Technology Center, ... visibility of his company an important priority since he ... to a social media marketing campaign launched ...
(Date:8/28/2014)... Nevada City, CA (PRWEB) August 28, 2014 ... and sanitation products for the food processing industry, is ... conducting a side-by side comparison of the E2 soap ... Q E2 Sanitizing Foam Soap . Hand hygiene ... pathogens in the food processing environment. Six key criteria ...
(Date:8/28/2014)... A new research platform uses a laser ... structures undergoing stress and heating, an approach ... for microelectronics and batteries., This new technique, ... how heating and the surface stress of ... have discussed the merits of surface-stress influence ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3
Cached News: