HOME >> BIOLOGY >> NEWS
NIAID Doctor Successfully Treats Longest Case Of Malaria Infection On Record

A mild case of malaria smoldered in a 74-year-old woman for decades before being correctly diagnosed and successfully treated by a research physician affiliated with the National Institute of Allergy and Infectious Diseases (NIAID), according to a report in this weeks New England Journal of Medicine.

The unusual case at more than 46 years, and possibly up to 71 years, the longest known malaria infection on record "reveals how high-tech medicine can shed light even on ancient syndromes," says Joseph M. Vinetz, M.D., a postdoctoral fellow in NIAIDs Laboratory of Parasitic Diseases.

Using an extremely sensitive test that searches for genetic signature sequences of a specific malaria parasite, Dr. Vinetz found evidence of that parasite that had eluded detection in multiple standard smears of blood taken from the patient and examined under a microscope. The genetic test, RT-PCR (reverse transcription-polymerase chain reaction), had recently been developed in the laboratory of an NIAID colleague, Thomas F. McCutchan, Ph.D., primarily for research purposes.

The woman, a native of Greece, came to Dr. Vinetz attention in February 1996 when her daughter, a resident of Baltimore, brought her mother for evaluation to a Johns Hopkins University clinic where Dr. Vinetz works part time. On examination, the woman did not complain of any symptoms but did have an enlarged spleen.

The enlarged spleen, her medical history indicated, was first documented several years earlier during a routine examination in Greece. At that time, she was mistakenly diagnosed with lymphoma and treated with an oral anti-cancer drug, methotrexate, for 10 days.

In response to the chemothera
'"/>

Contact: Laurie K. Doepel
ldoepel@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
4-Feb-1998


Page: 1 2 3

Related biology news :

1. TIGR and NIAID sign $65 million microbial sequencing contract
2. NIAID unveils bioterrorism research agenda
3. NIAID takes next genome step
4. NIAID awards grant to rapidly sequence the malaria mosquito genome
5. NIAID launches major step in trial of experimental shingles vaccine
6. NIAID-Supported Scientists Discover Origin Of HIV-1
7. NIAID Scientists Discover HIV Disease-Slowing Mutation
8. Doctors neckties: a reservoir for bacteria?
9. Doctors miss chances to help pregnant women quit smoking
10. Doctors miss chance to advise women of vitamin that prevents birth defects, survey finds
11. Doctors perform more IVF treatments, but multiple births decline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/6/2019)... ... June 05, 2019 , ... Ziegler, ... financial advisor to Pathologists Bio-Medical Laboratories (PBM) on its recent acquisition by PathGroup. ... platform that provides services to more than one dozen hospitals and surgery centers ...
(Date:6/4/2019)... Calif. (PRWEB) , ... June 04, 2019 , ... Harper ... was limping. X-rays revealed severe elbow dysplasia, which caused painful osteoarthritis in the ... her elbows. Her parents were heartbroken. , The surgical specialist, Dr. Christopher Eich ...
(Date:6/3/2019)... ... ... Stay on top of current hot topics through free webinars presented by ... is free, so be sure to register today to save your place! Participate in ... see our upcoming webinars: , CLINICAL TRIALS , June 10 – A Novel Approach ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... , ... May 30, 2019 , ... ... thinking on Data Integrity on July 08-09, 2019 in Boston, MA. This peer ... and medical device organizations. , The training will kick off with a compendial ...
(Date:5/21/2019)... ... May 21, 2019 , ... ... today officially opened the inaugural Africa Brewing Conference dedicated to sharing brewing knowledge, ... Africa. The event, which is supported through a partnership with “Ethiopia Invest”, will ...
(Date:5/14/2019)... ... , ... Gateway Genomics , a leading developer of prenatal and pediatric ... square feet. , “This past year has seen exponential growth for the sales ... Jacob. “The SneakPeek At-Home test, which is mailed directly to our customers who self-collect ...
(Date:5/4/2019)... ... May 03, 2019 , ... ... of the Diopsys® ffERG/Photopic Negative Response vision test, a new full ... 2050, it is estimated that 6.3 million Americans will have glaucoma, with black ...
Breaking Biology Technology:
Cached News: