HOME >> BIOLOGY >> NEWS
NIAID Doctor Successfully Treats Longest Case Of Malaria Infection On Record

A mild case of malaria smoldered in a 74-year-old woman for decades before being correctly diagnosed and successfully treated by a research physician affiliated with the National Institute of Allergy and Infectious Diseases (NIAID), according to a report in this weeks New England Journal of Medicine.

The unusual case at more than 46 years, and possibly up to 71 years, the longest known malaria infection on record "reveals how high-tech medicine can shed light even on ancient syndromes," says Joseph M. Vinetz, M.D., a postdoctoral fellow in NIAIDs Laboratory of Parasitic Diseases.

Using an extremely sensitive test that searches for genetic signature sequences of a specific malaria parasite, Dr. Vinetz found evidence of that parasite that had eluded detection in multiple standard smears of blood taken from the patient and examined under a microscope. The genetic test, RT-PCR (reverse transcription-polymerase chain reaction), had recently been developed in the laboratory of an NIAID colleague, Thomas F. McCutchan, Ph.D., primarily for research purposes.

The woman, a native of Greece, came to Dr. Vinetz attention in February 1996 when her daughter, a resident of Baltimore, brought her mother for evaluation to a Johns Hopkins University clinic where Dr. Vinetz works part time. On examination, the woman did not complain of any symptoms but did have an enlarged spleen.

The enlarged spleen, her medical history indicated, was first documented several years earlier during a routine examination in Greece. At that time, she was mistakenly diagnosed with lymphoma and treated with an oral anti-cancer drug, methotrexate, for 10 days.

In response to the chemothera
'"/>

Contact: Laurie K. Doepel
ldoepel@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
4-Feb-1998


Page: 1 2 3

Related biology news :

1. TIGR and NIAID sign $65 million microbial sequencing contract
2. NIAID unveils bioterrorism research agenda
3. NIAID takes next genome step
4. NIAID awards grant to rapidly sequence the malaria mosquito genome
5. NIAID launches major step in trial of experimental shingles vaccine
6. NIAID-Supported Scientists Discover Origin Of HIV-1
7. NIAID Scientists Discover HIV Disease-Slowing Mutation
8. Doctors neckties: a reservoir for bacteria?
9. Doctors miss chances to help pregnant women quit smoking
10. Doctors miss chance to advise women of vitamin that prevents birth defects, survey finds
11. Doctors perform more IVF treatments, but multiple births decline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/29/2019)... ... August 28, 2019 , ... ... have recently passed their five-year milestone of collaboration in salivary bioscience stress ... with a primary focus towards performing feasibility studies, phase 1 – phase ...
(Date:8/27/2019)... ... August 27, 2019 , ... ... opportunities to improve genetic testing guidelines. In the largest cohort study of its ... identify more at-risk patients. , Clinicians use guidelines to inform decisions about ...
(Date:8/25/2019)... ... August 23, 2019 , ... BioInformatics, part of ... solution: Experts-on-Demand. The service helps connect companies with a network of thousands of ... science, technology, and medicine is moving faster than ever, and we have built ...
Breaking Biology News(10 mins):
(Date:8/29/2019)... ... 28, 2019 , ... DuPont Nutrition & Biosciences will offer ... the International Baking Industry Expo, September 8 to 11, in booth 5015. DuPont ... cost and waste reduction and from maintaining freshness throughout shelf life to reformulating ...
(Date:8/23/2019)... Wis. (PRWEB) , ... August 22, 2019 , ... The ... some of the most harmful germs and pathogens on hard surfaces including E. Coli, ... leaves behind no chemical residues. For more information, visit the product page at rovingblue.com ...
(Date:8/8/2019)... FRANCISCO (PRWEB) , ... August 08, 2019 , ... ... Intelligent Virtual Agents for sales and service organizations, today announced that the ... Value Leadership Award for the IVA market . Inference will officially accept the ...
(Date:8/6/2019)... ... August 06, 2019 , ... The National Science Foundation ... a community project that will engage middle and early high school students in ... Youth-Led Citizen Science Network for Community Environmental Assessment.” Collaborative partners presenting the authentic ...
Breaking Biology Technology:
Cached News: