HOME >> BIOLOGY >> NEWS
NIAID-Supported Scientists Discover Origin Of HIV-1

Today scientists reported that they have discovered the origin of HIV-1, the virus responsible for the global AIDS pandemic. A subspecies of chimpanzees native to west equatorial Africa has been identified as the original source of the virus.

Beatrice H. Hahn, M.D., of the University of Alabama at Birmingham, a grantee of the National Institute of Allergy and Infectious Diseases (NIAID), led the international team of investigators. They describe their findings in the February 4 issue of Nature. The journal moved the normal press embargo ahead to coincide with Dr. Hahn's presentation of the study details on the opening night of the 6th Conference on Retroviruses and Opportunistic Infections in Chicago.

"This is an important finding with significant potential," notes Anthony S. Fauci, M.D., NIAID director. "We now have chimpanzee isolates of simian immunodeficiency virus [SIVcpz] that have been shown by careful molecular analysis to be closely related to HIV-1. Furthermore, this virus infects a primate species that is 98 percent related to humans. This may allow us -- if done carefully and in collaboration with primatologists working to protect this endangered species -- to study infected chimpanzees in the wild to find out why these animals don't get sick, information that may help us better protect humans from developing AIDS."

Until now, HIV-1's origin had been unclear. Although most scientists suspected that the virus descended from a primate species, only three chimpanzees infected with viruses related to HIV-1 had been documented, and one of these viruses correlated only weakly with HIV-1.

When Dr. Hahn and her collaborators recently identified a fourth chimpanzee infected with SIVcpz, they decided to use this opportunity to carefully examine all four viruses and the animals from which they were derived. With sophisticated genetic techniques, they analyzed the four SIVcpz isolates and compared them with various HIV-1 viruses taken
'"/>

Contact: Laurie K. Doepel
ldoepel@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
31-Jan-1999


Page: 1 2

Related biology news :

1. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
2. Scientists sequence genome of kind of organism central to biospheres carbon cycle
3. Scientists find nanowires capable of detecting individual viruses
4. Scientists discover potential new way to control drug-resistant bacteria
5. Scientists explore genome of methane-breathing microbe
6. Scientists decipher genetic code of biothreat pathogen
7. Stuck on you: Scientists lay bare secrets of bacterial attachment proteins
8. Scientists discover proteins involved in spread of HIV-1 infection
9. Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
10. Scientists reinvent DNA as template to produce organic molecules
11. Scientists visualise cellular handmaiden that restores shape to proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2019)... ... December 01, 2019 , ... ... greatest tools, technologies, and techniques to hit the life-science landscape. For more than ... products speeding work in laboratories and facilitating biological discovery. This year’s crop of ...
(Date:11/27/2019)... ... November 27, 2019 , ... The MyOnyx rehab ... (sEMG) sensors that measure and display muscle activity in real time. This information ... for treatment. Both patient and therapist can see when exercises are performed correctly ...
(Date:11/19/2019)... , ... November 19, 2019 , ... ... and sample preparation, and Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global ... in which Diagenode will offer Single-Cell ATAC-Seq (scATAC-Seq) Services, featuring Bio-Rad’s Droplet Digital ...
Breaking Biology News(10 mins):
(Date:12/4/2019)... ... 2019 , ... A new study released today in STEM CELLS outlines how ... (scar tissue) buildup – also improves the range of motion of the affected limb. ... mice. , The tumor-destroying capabilities of radiation therapy can be a life saver ...
(Date:11/27/2019)... ... 2019 , ... Silony Medical, a medical technology company producing ... in the UK. The procedure was performed in the UK’s largest trauma center, ... Dr. Alexander Montgomery. The surgery, which took place on July 22, 2019, was ...
(Date:11/19/2019)... ... November 19, 2019 , ... Supercomputing Conference – ... infrastructure solutions for Autonomous Vehicle , Medical Imaging, and Natural Language Processing ... with the Graphcore Poplar® software stack as part of its bare-metal cloud service ...
(Date:11/12/2019)... ... November 12, 2019 , ... Bode Technology (Bode) , ... Genealogy, Melinde Lutz Byrne, to the organization. Byrne’s team will strengthen efforts in ... to law enforcement through proven genealogy and DNA analysis methods. , Byrne’s hiring ...
Breaking Biology Technology:
Cached News: