HOME >> BIOLOGY >> NEWS
NIGMS center grants will spice up chemical libraries

ng director of NIGMS. "Ready access to these new methods will give biologists, in collaboration with chemists, the ability to obtain combinatorial libraries that are tailor-made to meet their specific research needs."

According to Dr. John M. Schwab, the NIGMS chemist who spearheaded the initiative, "Combinatorial chemistry uses massively parallel synthesis to rapidly assemble libraries. We are looking for new, highly efficient methods for synthesis, separation, purification, and analysis that will accelerate the creation of libraries and enable a broader range of structures to be made."

"Another key feature of the CMLD program is that each center must be highly integrated, featuring collaborative, synergistic projects," said Schwab. "This is not typical in the academic chemistry community. But experience has shown that unique insights can be gained when scientists approach a project from different perspectives."

The initiative comes at an opportune time, because recently developed automated screening tools allow scientists to sift through massive collections of compounds in short order. This approach was quickly adopted by the pharmaceutical industry, which routinely uses it to discover bioactive compounds that potentially could be developed into new drugs. Although industry has embraced the use of combinatorial chemistry, it rarely publishes new methods for generating libraries.

Of the chemical libraries that are available to the entire scientific community, many have been assembled using a small number of methods and core chemical scaffolds. That means they contain limited variety. The NIGMS effort seeks to enable the creation of truly unique and diverse, high-quality libraries through the development of new chemical methods. That, said Schwab, "will produce lasting benefits for all of biomedical science."


'"/>

Contact: Alisa Zapp Machalek
alisa.machalek@nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
10-Oct-2002


Page: 1 2

Related biology news :

1. NIGMS funds Center for Quantitative Biology
2. Lipids get the spotlight in new NIGMS Glue Grant
3. NIGMS and NSF grants join math and biology
4. NIGMS energizes NMR research with worlds biggest magnets
5. NIGMS Structural Genomics Awards scale up protein structure studies
6. NIGMS awards Glue Grant to create virtual cell
7. NIGMS Makes First Awards For
8. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
9. New Arizona State center brings science to policy on issues of water resources and urban growth
10. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
11. Brain has center for detecting sound motion

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NIGMS center grants will spice chemical libraries

(Date:12/19/2014)... LaunchKey , the first decentralized mobile authentication and authorization ... era, today announced the close of $3 million in ... Metamorphic Ventures with participation from ENIAC Ventures, Crosslink Capital, ... has raised $4 million to date, and will use ...
(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric data ... industry leaders such as Intel, Jabra, Atlas, and Scosche ... products. These products will be showcased at CES 2015, ... . "Our partners choose PerformTek ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... advances in technology, it is important to upgrade biometric ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... 2015  Transwestern | RBJ today announces the firm brokered a ... Shire a leading biopharmaceutical company, at Two Ledgemont Center in ... Robert Richards , president, and Brian Cohen , senior ... five-floor building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... January 22, 2015 Protocol Networks brings ... growing team of brand-neutral, independent consultants, Protocol Networks has ... explained that over the years, his company has attracted ... Town of Plainfield, as well as others. With the ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 zFlo Motion ... pleased to announce an exciting product from a new partner. ... analysis solutions over the past 15 years, with offerings in ... recently, their 3D IMU system (inertial measurement unit), iSen, is ...
Breaking Biology Technology:Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 23D Motion Capture Just Got Easy 2
Cached News: