HOME >> BIOLOGY >> NEWS
NIH awards $18.2m to The Burnham Institute to develop Center on Proteolytic Pathways

(La Jolla, CA) The National Institutes of Health ("NIH") has selected The Burnham Institute to develop a national resource for medical researchers to be known as the "Center on Proteolytic Pathways". A team directed by The Burnham's Jeffrey Smith, Ph.D., will receive $18.2 million over the next five years to develop this unique research hub.

The Center will consolidate all known and emerging knowledge about how proteins behave into "The Protease Pathway Interrogation Platform ('PIPP')". The platform, PIPP, will be the product of a multi-disciplinary team, including the Burnham Institute's Guy Salvesen, Ph.D., an expert on proteases and co-director of the center; Alex Strongin, Ph.D., a Professor at the Institute's Inflammation and Infectious Disease Center; Adam Godzik, Ph.D., Director of the Institute's Systems Biology Program, and Andrei Osterman, Ph.D., Professor in that same program. Collaborators on this effort include Drs. Mathew Bogyo from Stanford University, Bonnie Sloane of Wayne State University, and Lisa Coussens from the University of California at San Francisco.

Why study proteolytic pathways? Proteolysis, or how proteins break down, regulates the four fundamental aspects of cell behavior: division, death, differentiation, and motility. Understanding this process is critical to designing new therapies based on promoting or inhibiting cellular behaviors.

A particular strength of the Center is its emphasis on the use of activity-based proteomics to profile protease function. This approach, developed by Dr. Bogyo at Stanford, marks an innovation over other proteomics strategies because the activity-based approach reports on protease activity, as opposed to just abundance.

In practical terms, Dr. Smith envisions that technology developed within the Center "should ultimately help define the physiologic and pathophysiologic role of every human protease." Equally as significant, the Center will devise computatio
'"/>

Contact: Nancy Beddingfield
nbeddingfield@burnham.org
858-449-9940
Burnham Institute
30-Sep-2004


Page: 1 2

Related biology news :

1. Chemical engineering grad students will take notable national awards
2. NSF awards 22 new projects for plant genome research
3. The American Phytopathological Society announces 2004 awards
4. NSF announces six FIBR awards to tackle some of biologys most challenging questions
5. Two Virginia Tech energy-related inventions win R&D 100 awards
6. APS awards more than $140,000 to minority students of physiology
7. APS awards more than $36,000 to its 2004 undergraduate research fellows
8. 8 environmental stewards win $900,000 in biodiversity awards
9. UCSB professor and director receives two national awards
10. NSF awards $10 million in grants to ocean sites for long-term ecological research
11. Research to Prevent Blindness awards $4.8 million

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
(Date:4/5/2017)... 2017 Today HYPR Corp. , leading ... component of the HYPR platform is officially FIDO® ... security architecture that empowers biometric authentication across Fortune 500 ... secured over 15 million users across the financial services ... home product suites and physical access represent a growing ...
(Date:4/3/2017)... , April 3, 2017  Data captured ... engineering platform, detected a statistically significant association ... prior to treatment and objective response of ... potential to predict whether cancer patients will ... treatment, as well as to improve both pre-infusion ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... For the ... won a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to ... Experience from US2020. , US2020’s mission is to change the trajectory of STEM ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... process optimization firm for the life sciences and healthcare industries, announces a presentation ... San Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will ...
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting ... a professor in Harvard University’s Departments of Physics and Astronomy, has been selected for ... of the winning team for the 2015 Breakthrough Prize in Fundamental physics for the ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, featuring the ... and accompanying cloud-based bioinformatics software to perform Hi-C metagenome deconvolution using their ...
Breaking Biology Technology:
Cached News: