HOME >> BIOLOGY >> NEWS
NIH awards $18.2m to The Burnham Institute to develop Center on Proteolytic Pathways

(La Jolla, CA) The National Institutes of Health ("NIH") has selected The Burnham Institute to develop a national resource for medical researchers to be known as the "Center on Proteolytic Pathways". A team directed by The Burnham's Jeffrey Smith, Ph.D., will receive $18.2 million over the next five years to develop this unique research hub.

The Center will consolidate all known and emerging knowledge about how proteins behave into "The Protease Pathway Interrogation Platform ('PIPP')". The platform, PIPP, will be the product of a multi-disciplinary team, including the Burnham Institute's Guy Salvesen, Ph.D., an expert on proteases and co-director of the center; Alex Strongin, Ph.D., a Professor at the Institute's Inflammation and Infectious Disease Center; Adam Godzik, Ph.D., Director of the Institute's Systems Biology Program, and Andrei Osterman, Ph.D., Professor in that same program. Collaborators on this effort include Drs. Mathew Bogyo from Stanford University, Bonnie Sloane of Wayne State University, and Lisa Coussens from the University of California at San Francisco.

Why study proteolytic pathways? Proteolysis, or how proteins break down, regulates the four fundamental aspects of cell behavior: division, death, differentiation, and motility. Understanding this process is critical to designing new therapies based on promoting or inhibiting cellular behaviors.

A particular strength of the Center is its emphasis on the use of activity-based proteomics to profile protease function. This approach, developed by Dr. Bogyo at Stanford, marks an innovation over other proteomics strategies because the activity-based approach reports on protease activity, as opposed to just abundance.

In practical terms, Dr. Smith envisions that technology developed within the Center "should ultimately help define the physiologic and pathophysiologic role of every human protease." Equally as significant, the Center will devise computatio
'"/>

Contact: Nancy Beddingfield
nbeddingfield@burnham.org
858-449-9940
Burnham Institute
30-Sep-2004


Page: 1 2

Related biology news :

1. Chemical engineering grad students will take notable national awards
2. NSF awards 22 new projects for plant genome research
3. The American Phytopathological Society announces 2004 awards
4. NSF announces six FIBR awards to tackle some of biologys most challenging questions
5. Two Virginia Tech energy-related inventions win R&D 100 awards
6. APS awards more than $140,000 to minority students of physiology
7. APS awards more than $36,000 to its 2004 undergraduate research fellows
8. 8 environmental stewards win $900,000 in biodiversity awards
9. UCSB professor and director receives two national awards
10. NSF awards $10 million in grants to ocean sites for long-term ecological research
11. Research to Prevent Blindness awards $4.8 million

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by Solution ... Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to 2022", ... 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at a ... ... MarketsandMarkets Logo ...
(Date:4/11/2017)... 2017 NXT-ID, Inc. (NASDAQ:   NXTD ... the appointment of independent Directors Mr. Robin D. Richards ... of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief ... to their guidance and benefiting from their considerable expertise as ...
(Date:4/5/2017)... 4, 2017 KEY FINDINGS The ... at a CAGR of 25.76% during the forecast period ... primary factor for the growth of the stem cell ... MARKET INSIGHTS The global stem cell market ... and geography. The stem cell market of the product ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... analysis platform specifically designed for life science researchers to analyze and interpret ... Rosalind Franklin, who made a major contribution to the discovery of the ...
(Date:10/11/2017)... ... 11, 2017 , ... Proscia Inc ., a data ... titled, “Pathology is going digital. Is your lab ready?” with Dr. Nicolas Cacciabeve, ... and how Proscia improves lab economics and realizes an increase in diagnostic confidence.* ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer ... treatment of osteosarcoma. SBT-100 is able to cross the cell membrane and bind ...
(Date:10/10/2017)... International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, ... security market and how smart safety and security products impact the competitive ... Parks Associates: Smart Home Devices: Main ... "The residential security market has experienced continued ...
Breaking Biology Technology:
Cached News: