NIH funds synchrotron beamlines to advance studies of molecular structures

"If you build it, they will come."

This statement is certainly true in synchrotron-based X-ray crystallography, an area of study committed to solving detailed structures of molecules. The field has exploded in recent years, and a major threat to its continued growth is limited synchrotron resources.

Synchrotrons are the enormous machines that produce powerful X-rays used by researchers to tease apart the three-dimensional structures of molecules. The scientists must schedule their data-collection visits to synchrotrons months in advance. They must then work feverishly before and during these few days to make the best use of their scarce synchrotron "beam time."

To advance structural studies of biological molecules, the National Institute of General Medical Sciences (NIGMS) and the National Cancer Institute (NCI) are supporting the design and construction of a user facility consisting of three new beamlines at Argonne National Laboratory's Advanced Photon Source, the newest and most advanced synchrotron in the country.

This new facility will be custom designed and constructed by ACCEL GmbH, a company located in Bergish Gladbach, Germany. NIGMS and NCI plan to spend a total of around $23 million on the project and estimate that the three beamlines will be fully operational in about three years.

"The primary motive for the project is to benefit the scientific community by facilitating access to synchrotron beamlines. This is particularly important as the structural genomics effort at NIGMS begin to pick up speed," said Dr. Marvin Cassman, director of NIGMS.

NCI is particularly interested in how the synchrotron facilities will advance the study of cancer-related molecules. "A detailed understanding of protein structure will help cancer researchers develop drugs targeted to specific types of cancer," said Dr. Dinah Singer, director of NCI's Division of Cancer Biology.

X-ray crystallographers determine t

Contact: Alisa Zapp Machalek
NIH/National Institute of General Medical Sciences

Page: 1 2

Related biology news :

1. NIGMS funds Center for Quantitative Biology
2. $5 million grant funds partnership, studies of minority-based issues in reproductive health
3. NIH funds new Boston College-Boston University study of B-1a cell associated with leukemia
4. NSF funds summer research program abroad for undergraduates at UC San Diego
5. Research to create lung-cancer blood tests receives $3.4M in Pennsylvania tobacco settlement funds
6. The DFG funds a new research vessel
7. NIH funds Breast Cancer and the Environmental Research Center at Fox Chase Cancer Center
8. Grant funds research to develop tissue-engineered solutions for heart disease
9. Stuart research funds generating dividends for veterinary medicine
10. Grant funds research to develop microbicide barrier to HIV
11. $24-million grant funds local researchers to create encyclopedia of the innate immune system

Post Your Comments:

(Date:11/13/2018)... , ... November 12, 2018 ... ... Park-based management consulting firm specializing in the life sciences, healthcare, and technology ... for Cybersecurity and Compliance. Summerville will be responsible for overseeing CREO’s work ...
(Date:11/13/2018)... (PRWEB) , ... November 13, ... ... among the nation’s largest Phase I-IV clinical trial site service companies in ... physician-owned orthopedic practices in North Carolina, and a leading provider of innovative, ...
(Date:11/9/2018)... ... November 08, 2018 , ... Boekel Scientific ... blocks, also known as dry bath incubators are used in laboratories worldwide for ... , For the new heating blocks, Boekel Scientific used the same interface design ...
Breaking Biology News(10 mins):
(Date:11/5/2018)... ... 05, 2018 , ... USARAD Holdings Inc., the leading US ... healthcare VC firms announces at Distributed Health 2018 conference November 5-6 (Nashville, TN) ... and obtaining its first radiology interpretations, one of the first known true use ...
(Date:11/5/2018)... Ill. (PRWEB) , ... November 05, 2018 , ... ... Inc., for access to 2Blades’ Transcription Activator Like (TAL) effector code technology for ... for commercial uses of the technology in plants. Since its discovery in 2009, the ...
(Date:11/3/2018)... (PRWEB) , ... November 01, 2018 , ... Triangle Insights ... Inc. Magazine as one of the fastest-growing private companies in the United States, appearing ... 5000 list ranks private companies based on percentage revenue growth over the previous three ...
(Date:10/31/2018)... ... October 30, 2018 , ... ... trial at the Campbell Clinic in Memphis, Tennessee. This study enrolled 125 ... standard of care for managing pain after total knee replacement surgery (TKA). , ...
Breaking Biology Technology:
Cached News: