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NIH launches first center in Nationwide Chemical Genomics Network

ar function in a cell, while others may have the opposite effect or no effect at all. In addition to cells and proteins, the Kalypsys system will offer researchers the ability to screen small, whole organisms, such as zebrafish embryos or yeast, against a large array of chemical compounds. A high-resolution photo and a low-resolution video of the Kalypsys system are available at: http://www.genome.gov/10005141.

Data gleaned from the screening effort will shed new light on the function of various genes and the roles that specific genes play in pathways crucial to biological function. Ultimately, researchers hope the information generated by the chemical genomics network will identify new targets for therapy and tools to study them, thereby enabling such targets to move more rapidly through the drug development pipeline.

Also today, Dr. Austin announced that Jim Inglese, Ph.D., has been appointed head of biomolecular screening in the NIH Chemical Genomics Center. "We are very excited that a researcher of Dr. Inglese's stature in the pharmaceutical and chemical genomics communities is joining our team. His expertise in high-throughput screening technologies and assay development will be a tremendous asset to our center," said Dr. Austin, noting that Dr. Inglese comes to NHGRI from Merck Research Laboratories in North Wales, Pa., where he was a senior research fellow in the automated biotechnology group.

Dr. Inglese received a B.S. in Chemistry from the Rensselaer Polytechnic Institute, Troy, N.Y., in 1984, and a Ph.D. in Organic Chemistry from Pennsylvania State University, University Park, Pa., in 1989. He is the founding editor and editor-in-chief of the peer-reviewed journal, ASSAY and Drug Development Technologies.

About the NIH Roadmap for Medical Research

The NIH Roadmap is a series of far-reaching initiatives designed to transform the nation's medical research capabiliti
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Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
9-Jun-2004


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