HOME >> BIOLOGY >> NEWS
NIST's new way of 'seeing': A neutron microscope

A prototype microscope that uses neutrons instead of light to "see" magnified images has been demonstrated at the National Institute of Standards and Technology (NIST). Neutron microscopes might eventually offer certain advantages over optical, X-ray and electron imaging techniques such as better contrast for biological samples.

Described in the July 19 issue of Applied Physics Letters, the imaging process involves hitting a sample with an intense neutron beam. The neutrons that pass through--whose pattern reflects the sample's internal structure--are directed into a row of 100 dimpled aluminum plates. Each dimpled plate acts like a weak focusing lens for neutrons, diverting the neutrons' path slightly at each interface. The image then is projected onto a detector. Adelphi Technology Inc. of San Carlos, Calif., designed and demonstrated the microscope with the help of NIST scientists, who routinely use multiple lenses to focus neutron beams for other research.

In principle, neutrons could provide better image resolution than visible light because they have shorter wavelengths---as short as 1 nanometer (nm) compared to 400-700 nm. In this demonstration at NIST's Center for Neutron Research, the microscope produced a resolution of only 0.5 millimeters and a magnification of about 10. However, Adelphi hopes to substantially improve image resolution through research to reduce lens aberrations. The company also hopes to build a compact, laboratory-scale neutron source.

Moreover, neutrons offer some unique advantages. Unlike other imaging methods, neutrons interact strongly with hydrogen, an important component of biological samples composed mostly of hydrocarbons and water. And neutrons easily penetrate samples, thereby reducing artifacts produced with other techniques requiring thin slices, staining or fixing.

Stanford University also participated in the research, which was supported in part by the U.S. Department of Energy.


'"/>

Contact: Laura Ost
laura.ost@nist.gov
301-975-4034
National Institute of Standards and Technology (NIST)
30-Jul-2004


Page: 1

Related biology news :

1. How cold! New partnership to use chilled neutrons
2. Radiating relief: Researcher combats stubborn arthritis with neutrons
3. Maine-based biophysics institute gets funding for first US-based 4Pi nanoscale microscope
4. Plant disease under the homeland security microscope
5. New DVD virtual microscope at UNC-Chapel Hill
6. Multiphoton microscope observes cell membrane action
7. Atomic force microscope used to measure how well live bacteria stick
8. UT Southwestern gets new cryo-electron microscope
9. Fungi family tree goes under the microscope
10. Atomic force microscope powerful new tool for measurement of particle attraction
11. New microscope technology allows study of biomolecules interacting with minerals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2016)... , Feb. 11, 2016  According to new research ... mainstream. More than 200 fingerprint, iris, and eye-vein ... under 70 brand names. This includes market leaders ... ZTE. Acuity projects that 600 million biometric smartphones ... global installed base. Maxine Most , ...
(Date:2/11/2016)...  Vigilant Solutions announces today that its license plate recognition ... Lee,s Summit Police Department to improve ... of a homicide suspect. Kansas City ... square miles and is home to roughly 100,000 residents. ... mobile license plate reader system and also leverages Vigilant,s network ...
(Date:2/10/2016)... India , February 10, 2016 /PRNewswire/ ... --> According to 2016 iris recognition ... identification iris recognition is more widely accepted ... available with both fingerprint and iris recognition ... the user to avoid purchasing two individual ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... ... , ... Global Stem Cells Group has announced an inaugural conference ... Quito, Ecuador, Feb. 24-March 6, 2016. The new facility will provide advanced protocols and ... Stem Cells Group CEO Benito Novas will host the event, which will begin with ...
(Date:2/12/2016)... , Feb. 12, 2016 Biocom, the association representing ... took a group of San Diego ... of its 2016 Precision Medicine Advocacy Fly-In. Biocom Fly-In participants ... and Drug Administration (FDA), the Centers for Medicare and Medicaid ... as San Diego U.S. Representatives Susan Davis and ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Pittcon 2016 Exposition, which ... will include 848 exhibitors (count as of February 9) of which 119 are ... used by the scientific community in industrial, academic, and government labs. The Exposition ...
(Date:2/12/2016)... , Feb. 12, 2016  BD (Becton, Dickinson and ... technology company, today announced the launch of the BD ... and Technology (AGBT) Meeting. --> ... genomic research by providing cost effective NGS library preparation ... a high-throughput, fully integrated, next generation sequencing (NGS) library ...
Breaking Biology Technology:
Cached News: