NTP-CERHR announces the Second Phthalates Expert Panel Meeting to be held December 15-17, 1999

NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) will hold the second meeting of an Expert Panel to evaluate seven phthalate esters -- or plasticizers-- December 15-17, 1999 at the Hawthorn Suites (Research Triangle Park), 300 Meredith Drive, Durham, North Carolina 27713. The meeting will convene 8:30 a.m., Wednesday, December 15 and will end at approximately 3 p.m. on December 17.

The purpose of the meeting is to complete the integrated evaluation documents that were begun during the meeting held August 17-19, 1999 in Alexandria, Virginia and to draft summary statements on the seven phthalate esters. The seven phthalates being reviewed are butyl benzyl phthalate, di(2-ethylhexyl) phthalate, di-isodecyl phthalate, di-isononyl phthalate, di-n-butyl phthalate, di-n-hexyl phthalate, and di-n-octyl phthalate. At the completion of the first meeting, integrated evaluation documents were drafted and reviewed by the full Panel for the following 3 phthalates: butyl benzyl phthalate, di(2-ethylhexyl)phthalate, and di-n-octyl phthalate. These previously written integrated evaluations and the four new ones (di-isodecyl phthalate, di-isononyl phthalate, di-n-butyl phthalate, and di-n-hexyl phthalate) will be discussed at the Expert Panel meeting being held December 15-17. Following agreement on the integrated evaluations, summary statements reflecting significant conclusions and judgements for each of the phthalates will be developed and agreed to by the entire Panel. These narrative statements will reflect a consensus opinion of the Panel as to the developmental and reproductive toxicity of these chemicals in experimental models and will address the potential significance of these results to human reproduction and development.

The Phthalate Panel Members are: Robert Kavlock, PhD (Chair) EPA/ORD; Kim Boekelheide, MD, PhD, Brown University; Robert Chapin, PhD, NIEHS; Michael Cunningham, PhD, NIEHS

Contact: Bill Grigg
NIH/National Institute of Environmental Health Sciences

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