HOME >> BIOLOGY >> NEWS
Nabi Biopharmaceuticals begins human testing of novel vaccine to fight nicotine addiction

Rockville, Maryland, June 12, 2002 Nabi Biopharmaceuticals (Nasdaq: NABI) announced today that they have initiated NicVAX™ (Nicotine Conjugate Vaccine) phase I testing in humans. NicVAX is a proprietary and novel investigational vaccine designed to help the body develop antibodies that bind to nicotine and block it from reaching the brain. If shown to be safe and effective in subsequent clinical trials, NicVAX may help millions of people worldwide kick their addiction to cigarettes and tobacco products.

"NicVAX is an entirely new approach to fighting and preventing nicotine addiction," said David J. Gury, Nabi Biopharmaceuticals chairman, president and chief executive officer.

Of the 48 million adult U.S. smokers, about 70 percent, or nearly 34 million people have made at least one attempt to stop, yet only 1.2 million quit permanently, according to the U.S. Centers for Disease Control and Prevention.

"The reason quitting smoking is so difficult is because nicotine is highly addictive," according to Robert Naso, Ph.D., Nabi Biopharmaceuticals senior vice president of quality, regulatory and product development. "When a person smokes, nicotine enters the body and goes straight to the brain, where it generates positive sensations, such as pleasure and relaxation. However, the body does not develop antibodies against nicotine, no matter how much or for how long a person smokes. Based on earlier animal studies, NicVAX is a technology that enables the body to develop antibodies to nicotine. We believe that these antibodies, acting much like a sponge, will soak up the nicotine, preventing it from reaching the brain."

"By reducing the amount of nicotine available to stimulate the brain's pleasure centers, an immunized tobacco user would theoretically receive no positive reinforcement from nicotine use," according to Dr. Naso. In pre-clinical animal studies NicVAX generated antibodies that reduced nicotine levels in the brain by
'"/>


12-Jun-2002


Page: 1 2

Related biology news :

1. New hydrothermal vents discovered as South Pacific Odyssey research begins
2. DCI donor services begins distribution of tissue implants
3. Landmark, pivotal Phase IIb/III trial of biotoxin for cancer pain begins
4. Work begins on powering a sustainable future for the UK
5. As autumn approaches, this chickadees brain begins to expand
6. New study begins to unravel fate of toxic pollutants harbored in Arctic waters
7. UCSF begins distributing the first of its two embryonic stem cell lines
8. Acorda Therapeutics begins Phase 3 trials of Fampridine-SR for chronic spinal cord injury
9. The pathway to anxiety begins early in life
10. DOE begins international effort to sequence tree genome
11. Montana State University begins major trout and salmonid book collection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/9/2019)... ... July 08, 2019 , ... ... the biotechnology hub of Cambridge, MA. This expansion strengthens KMK’s presence for the ... , and sales force effectiveness consulting for the biotechnology corridor. With ...
(Date:7/5/2019)... ... July 05, 2019 , ... SteriTrack Inc. is ... Platform to governments around the world. , Powered by Microsoft Azure, the ... care solutions to operating theatres worldwide to address new global regulations mandating all ...
(Date:6/25/2019)... ... June 25, 2019 , ... ActX has launched a medical ... from 23andMe, customers can get access to professionally reviewed genetic screening similar to ... Ancestry and Health + Ancestry customers., With the ActX + 23andMe service, both ...
Breaking Biology News(10 mins):
(Date:5/4/2019)... ... May 03, 2019 , ... More ... the Dakila Pesquisas Association, the scientist and ufologist Urandir Fernandes de Oliveira, last ... Urandir detailed the results of some research carried out by the association, in ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... REPROCELL USA Inc. has demonstrated its ability to provide various services and ... to enhance customer satisfaction through the effective implementation of its quality management ...
(Date:5/2/2019)... TORONTO (PRWEB) , ... May 02, 2019 , ... Stay ... pharma, biotech, medical device and food industries. Access to all webinars is free, so ... stay relevant in your field! , Visit http://www.xtalks.com to see our upcoming ...
(Date:5/2/2019)... (PRWEB) , ... May 02, 2019 , ... ... transplantation clinic in the greater Boston area. Gone are the days of painful ... ARTAS® iX Robotic Hair Restoration System is the only robotic intelligent solution to ...
Breaking Biology Technology:
Cached News: