HOME >> BIOLOGY >> NEWS
Nanosphere announces genetic detection advance in Nature Biotechnology

NOTE TO REPORTERS/EDITORS: The embargo on this press release has been changed since it was originally posted.

Nanosphere Inc. today announced researchers have developed a colorimetric detection capability for its nanoparticle-based molecular detection systems that will further simplify the identification of genomic DNA, RNA and protein targets without the need for traditional signal or target amplification. Findings are published in the July 2004 issue of Nature Biotechnology (available on-line May 30, 2004, www.nature.com/nbt).

Nanosphere researchers evaluated the addition of colorimetric detection to its ClearReadTM technology in the identification of the mecA gene, a biomarker widely associated with clinically challenging methicillin resistant Staphylococcus aureas (MRSA). Among results, researchers observed a green-to-orange color change that detected the presence of the targeted mecA sequence from clinical samples of MRSA. Further, the high detection sensitivity and specificity of the colorimetric assay enabled testing to be performed without using amplification procedures.

"Nanosphere's technology addresses a tremendous unmet need for greater simplicity in molecular testing," said Vijaya Vasista, Nanosphere's Chief Operating Officer. "This colorimetric detection also adds to the flexibility of Nanosphere's platform, as it can be leveraged for the detection of various targets at extremely low concentrations, either visually or in conjunction with Nanosphere's genomic detection instruments."

At the core of Nanosphere's technology, gold nanoparticles are attached to strands of nucleotides complementary to targets of interest, and when a target nucleic acid or protein is present, the nanoparticle probes latch on to the match and provide a strong optical signal indicating the target has been found. The unique hybridization characteristics of gold nanoparticle probes result in sharp me
'"/>

Contact: Wendy Emanuel
pr@nanosphere.us
773-255-9580
Nanosphere, Inc.
1-Jun-2004


Page: 1 2

Related biology news :

1. Nanosphere announces DNA detection breakthrough published in Science
2. Secretary of Energy announces seven E.O. Lawrence Award Winners
3. Popular Science announces Third Annual Brilliant 10
4. The American Phytopathological Society announces 2004 awards
5. NSF announces six FIBR awards to tackle some of biologys most challenging questions
6. Protemix corporation announces discovery of way to repair hearts damaged by diabetes
7. JGI announces community sequencing program portfolio
8. APS announces the winners of its 2004 postdoctoral fellowship in physiological genomics
9. National Corn Growers Association announces valuable maize genome data now available to scientists
10. DFG announces three percent budget increase
11. Chemical Society announces EPA awards for environmentally friendly technology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2020)... ... August 19, 2020 , ... ... and expo uniting life science, data science, informatics and IT leaders goes VIRTUAL ... this period of uncertainty and change, Bio-IT takes the leadership role of keeping ...
(Date:8/7/2020)... Ky. (PRWEB) , ... August 06, 2020 , ... ... selected to participate in the prestigious National STEM Scholar Program, a unique professional ... network building, and project support for middle school science teachers nationwide. , Created ...
(Date:7/22/2020)... ... July 21, 2020 , ... USDM ... technology and compliance, announces a new solution to manage regulated workloads on Microsoft ... of their technology stack complies with FDA and global regulations. USDM's new managed ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... therapy, today announced the hiring of Allen R. Nissenson, M.D., F.A.C.P., as its ... the clinical development of Sentien’s lead product, SBI-101. Dr. Nissenson serves as ...
(Date:7/1/2020)... ... June 29, 2020 , ... MedShift , ... in 2020, despite many obstacles created as a result of COVID-19. As a ... its partnered medical practices and medical manufacturers by expanding access to device offerings, ...
(Date:6/28/2020)... , ... June 25, 2020 , ... The Indoor Lab, ... of Safe Space™ for businesses of all types to ensure cleanliness, distancing and occupancy ... , A Safe Space™ enabled business will provide a health performance index system ...
Breaking Biology Technology:
Cached News: