HOME >> BIOLOGY >> NEWS
Nasal antibiotic ointment reduces infection risk after surgery

In what may be the largest clinical trial to evaluate the effectiveness of antimicrobial agents in preventing surgical wound and hospital-based infections caused by Staphylococcus aureus, scientists at the University of Iowa and Johns Hopkins found that an antibiotic ointment, called mupirocin (moo-PIE-roe-sin), smeared inside the nose cut infection rates in half or better.

"Our results carry tremendous implications for reducing S. aureus surgical wound and other hospital-based infections, and for preventing illness and saving lives," says Trish Perl, M.D., associate professor of medicine, director of Hospital Epidemiology and Infection Control at Hopkins and an author of the study published in the June 13 issue of the New England Journal of Medicine.

Staphylococcus aureus is a widely distributed germ that normally resides in the nostrils of an estimated 25 to 30 percent of all hospitalized patients without causing harm. But it can contaminate surgical sites, causing severe and often deadly infections, especially in people with weakened immune systems, and contributing millions of dollars yearly to the costs of health care.

In the study, called MARS (for Mupirocin and the Risk of Staphyloccus aureus Infections), the researchers determined the rate of S. aureus surgical wound infections and other hospital-based infections in 4,030 adult patients who underwent various elective surgical procedures at the University of Iowa Hospitals and Clinics and the Veteran's Affairs Medical Center in Iowa City. Mupirocin antibiotic ointment, or a placebo, was applied to the inside of the nostrils twice daily for up to five days before surgery. Patients were followed for 30 days after surgery to determine if they acquired S. aureus infections.

While mupirocin ointment, made by GlaxoSmithKline, is highly effective at reducing the rate of S. aureus infections in patients undergoing surgery, as with any antibiotic, there is the risk of widespread r
'"/>

Contact: Trent Stockton
tstockt1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
12-Jun-2002


Page: 1 2

Related biology news :

1. Nasal contribution to breathing with exercise: The effect of race and gender
2. Could A Nasal Vaccine Finally Get Rid Of The Black Death?
3. Study Shows Athletes Get No Kick From Nasal Strips
4. Anthrax enzyme images reveal secrets of antibiotic resistance, suggest new drug design
5. Smart antibiotics may result from UCLA research
6. K-State researcher working to improve alternatives to equine antibiotics
7. Bacterial protein recycling factor possible key to new class of antibiotics
8. Bacteria spill their guts to aid researchers in quest for new antibiotics
9. Molecule that blocks key bacterial enzyme may lead to new antibiotics
10. Does antibiotic use contribute to allergies?
11. Tigecycline - Candidate antibiotic produces 74 percent cure rate in cSSSI patients

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nasal antibiotic ointment reduces infection risk after surgery

(Date:12/10/2014)... RALEIGH, N.C. , Dec. 9, 2014  Valencell, ... announced it is seeing a staggering demand from its ... demand, the Company revealed, is not solely coming from ... industries as well. "A wearable is only ... a result, accuracy is the ultimate driver in long-term ...
(Date:12/10/2014)... Dec. 9, 2014 CIE San Diego has ... provides the connective tissue that enhances care coordination among ... easily share client-level information; earned a second $1 million ... organizations serving seniors aging in community and; will be ... December 11 th 4-6p. CIE San ...
(Date:12/10/2014)... 2014     ...   Jifflenow, a leading ... for business-to-business (B2B) events, today announced a partnership ... near-field communication (NFC), Bluetooth low energy (BLE), and ... , Jifflenow will integrate its meeting ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
(Date:12/19/2014)... 18, 2014 iLab Solutions, the global ... of Siri Bryant as the new Director of Institutional ... Core Implementations. These two new leadership positions were created ... by ensuring that iLab continues to meet the needs ... four years, iLab has been deployed at over 450 ...
(Date:12/19/2014)... BURLINGTON, Mass. , Dec. 18, 2014  Decision ... dental biomaterial market will grow moderately through ... implant procedures and growing awareness of dental biomaterials all ... underdeveloped markets such as China ... incomes will bring dental procedures within reach for a ...
(Date:12/17/2014)... December 16, 2014 The Activated ... 2013, which is why IBISWorld updated its original industry ... to benefit from an intensified focus on environmental policy. ... new emission standards for power plants and a range ... to IBISWorld Industry Analyst Sarah Kahn, “a range of ...
(Date:12/17/2014)... 17, 2014 Ipsen Biopharmaceuticals, Inc., ... ADR: IPSEY), today announced that Somatuline® ... Somatuline®) was approved by the U.S. Food and ... neuroendocrine tumors (GEP-NETs) in adult patients with unresectable, ... disease to improve progression-free survival (PFS). , “The ...
Breaking Biology Technology:iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 8
Cached News: