HOME >> BIOLOGY >> NEWS
Natural antifreeze yields secrets

Fish in the icy seas around the North Pole and Antarctica thrive in temperatures that would freeze most animals to death in minutes. Their secret: blood proteins that act as a natural antifreeze.

Now researchers at the University of California, Davis, are closing in on just how those proteins work. The research could lead to safer storage for food or blood products. It may also help scientists understand how bones and sea-shells are made and how mineral deposits can cause kidney stones and heart disease.

The antifreeze proteins studied at UC Davis, called antifreeze glycoproteins, are long, floppy and covered in sugar molecules that interact with water. Using nuclear magnetic resonance and infrared spectroscopy, Nelly Tsvetkova and colleagues in the UC Davis Biostabilization Laboratory have found that even in ice as cold as minus 60 degrees Celsius (minus 76 F), the proteins are surrounded with a shell of liquid water and are constantly moving and changing shape.

"Normally at this temperature, proteins are pretty much solid," said Yin Yeh, professor of applied science at UC Davis. The random structure stops ice crystals from growing and preserves liquid water around the protein, said John Crowe, who with Fern Tablin of the UC Davis School of Veterinary Medicine heads the biostabilization group.

The antifreeze proteins also stabilize cell membranes during chilling, Crowe said. As the temperature drops, the fatty molecules that make up the cell membrane change from a semi-fluid to a gel-like state. As this happens, cell contents can leak out. In another recent paper from the UC Davis group, graduate student Melanie Tomczak, now a researcher at Queen's University in Kingston, Ontario, showed that antifreeze proteins bind to specific sugars on the cell membrane and change its structure, preventing leakage.

The antifreeze glycoproteins were discovered by UC Davis biochemist Robert E. Feeney over 30 years ago. Crowe and Tablin
'"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
15-Mar-2002


Page: 1 2

Related biology news :

1. Natural mineral locks up carbon dioxide
2. Naturalists of the Isthmus of Panama
3. Natural selection at work in genetic variation to taste
4. Natural, man-made mix promises biggest landscape plant growth
5. Natural enemies help scientists untangle tropical forest food webs
6. Natural killer cellers are made, not born
7. Natural selection in a nutshell
8. Natural fat compound may be basis for new class of drugs targeting obesity
9. Natural hormone could reverse heart damage
10. New biography details adventures of Fritz Muller, A Naturalist in Brazil
11. Natural selections fingerprint identified on fruit fly evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/20/2018)... ... November 20, 2018 , ... Like many large breed ... Before he was a year old, his mom, Rebecca, noticed he was slow ... examined by her veterinarian and her suspicions were confirmed: Jack had bilateral hip dysplasia, ...
(Date:11/15/2018)... ... November 15, 2018 , ... Firmex today released new research on ... over 480 investment bankers and M&A advisors worldwide to compile the third annual ... the key findings in the report. , Highlights in the 2018-19 Report:, ...
(Date:11/14/2018)... ... 14, 2018 , ... In recognition of World Diabetes Day, Diopsys is lending ... The company is reaching out to help educate patients and the healthcare community about ... vision testing for people with the disease. , The American Diabetes Association (ADA) released ...
Breaking Biology News(10 mins):
(Date:11/26/2018)... ... 26, 2018 , ... USARAD Holdings Inc., the leading US ... (Virtual Radiologic founders) among other healthcare investors exhibits at the Radiological Society of ... Chicago. The company is proud to announce a 10 year anniversary since its ...
(Date:11/15/2018)... ... November 14, 2018 , ... Hüpnos announces the ... the public. It is estimated that 90 million Americans suffer from ... partner. The resulting daytime fatigue causes extreme difficulty with concentration, focus and memory. ...
(Date:11/13/2018)... ... November 13, 2018 , ... , Park Systems, world leader in Atomic Force ... growing demand for AFM technology in China, Park Systems has decided to provide direct ... in Beijing equipped with Park AFM. , The Grand Opening of the Park Beijing ...
(Date:11/9/2018)... PHILADELPHIA (PRWEB) , ... November 08, 2018 , ... ... system integrator of custom industrial automation and IT solutions with 140 employees on ... at Automation Fair®, taking place at the Pennsylvania Convention Center on November 14 ...
Breaking Biology Technology:
Cached News: