HOME >> BIOLOGY >> NEWS
Natural antifreeze yields secrets

Fish in the icy seas around the North Pole and Antarctica thrive in temperatures that would freeze most animals to death in minutes. Their secret: blood proteins that act as a natural antifreeze.

Now researchers at the University of California, Davis, are closing in on just how those proteins work. The research could lead to safer storage for food or blood products. It may also help scientists understand how bones and sea-shells are made and how mineral deposits can cause kidney stones and heart disease.

The antifreeze proteins studied at UC Davis, called antifreeze glycoproteins, are long, floppy and covered in sugar molecules that interact with water. Using nuclear magnetic resonance and infrared spectroscopy, Nelly Tsvetkova and colleagues in the UC Davis Biostabilization Laboratory have found that even in ice as cold as minus 60 degrees Celsius (minus 76 F), the proteins are surrounded with a shell of liquid water and are constantly moving and changing shape.

"Normally at this temperature, proteins are pretty much solid," said Yin Yeh, professor of applied science at UC Davis. The random structure stops ice crystals from growing and preserves liquid water around the protein, said John Crowe, who with Fern Tablin of the UC Davis School of Veterinary Medicine heads the biostabilization group.

The antifreeze proteins also stabilize cell membranes during chilling, Crowe said. As the temperature drops, the fatty molecules that make up the cell membrane change from a semi-fluid to a gel-like state. As this happens, cell contents can leak out. In another recent paper from the UC Davis group, graduate student Melanie Tomczak, now a researcher at Queen's University in Kingston, Ontario, showed that antifreeze proteins bind to specific sugars on the cell membrane and change its structure, preventing leakage.

The antifreeze glycoproteins were discovered by UC Davis biochemist Robert E. Feeney over 30 years ago. Crowe and Tablin
'"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
15-Mar-2002


Page: 1 2

Related biology news :

1. Natural mineral locks up carbon dioxide
2. Naturalists of the Isthmus of Panama
3. Natural selection at work in genetic variation to taste
4. Natural, man-made mix promises biggest landscape plant growth
5. Natural enemies help scientists untangle tropical forest food webs
6. Natural killer cellers are made, not born
7. Natural selection in a nutshell
8. Natural fat compound may be basis for new class of drugs targeting obesity
9. Natural hormone could reverse heart damage
10. New biography details adventures of Fritz Muller, A Naturalist in Brazil
11. Natural selections fingerprint identified on fruit fly evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... April 5, 2017 Today HYPR Corp. ... the server component of the HYPR platform is officially ... the end-to-end security architecture that empowers biometric authentication across ... has already secured over 15 million users across the ... of connected home product suites and physical access represent ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... Lithuania, announced today that they have entered into a multiyear collaboration to identify ... CRISPR researchers with additional tools for gene editing across all applications. , Under ...
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS announces expanded coverage of ... newest module, US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and ... synthetic sealants and biologic sealants used in surgical applications. BioMedGPS estimates the market ...
(Date:10/12/2017)... Diego, CA (PRWEB) , ... ... ... (https://www.onramp.bio/ ) has launched Rosalind™, the first-ever genomics analysis platform specifically ... all bioinformatics complexity. Named in honor of pioneering researcher Rosalind Franklin, who ...
(Date:10/11/2017)... ... October 11, 2017 , ... The ... endogenous context, enabling overexpression experiments and avoiding the use of exogenous expression plasmids. ... is transformative for performing systematic gain-of-function studies. , This complement to loss-of-function ...
Breaking Biology Technology:
Cached News: