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Nerves, heal thyselves

eus. The protein complex gains easy entrance to the nucleus due to the presence of importin alpha and beta. The researchers found that blocking this newly uncovered process inhibits nerve regeneration (photos available).

The identification of the proteins containing the "healing message" and of the genes that enable the healing response is the next step in unlocking the mystery of peripheral nerve regeneration.

Since the central and peripheral systems are connected to each other, the ability to transfer substances within the peripheral nervous system could one day offer a springboard from which to introduce therapeutic agents into the brain and spinal cord.

Dr. Michael Fainzilber's research is supported by the Y. Leon Benoziyo Institute for Molecular Medicine, the Irwin Green Alzheimer's Research Fund, the Koshland Research Fund, and the Buddy Taub Foundation. Dr. Fainzilber is the incumbent of the Daniel E. Koshland Sr. Career Development Chair.


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Contact: Alex Smith
Alex_smith@margeotes.com
212-460-0563
American Committee for the Weizmann Institute of Science
20-Jan-2004


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