HOME >> BIOLOGY >> NEWS
Neural stem cells can develop into functional neurons

Researchers have found that neural stem cells isolated from the brains of adult rats can mature into functional neurons. Stem cells, which are found in tissues throughout the body, are immature progenitor cells that give rise to more specialized cells that form tissues and organs.

The scientists emphasized that although their studies show that adult stem cells have the capacity to develop into functioning brain cells, their findings do not mean that clinical application of adult neural stem cells is imminent. The studies were published April 15, 2002, in an advance online article in Nature Neuroscience by Howard Hughes Medical Institute (HHMI) investigator Charles F. Stevens and colleagues Hong-jun Song, an HHMI research associate, and Fred H. Gage at The Salk Institute.

According to Stevens, previous experiments showed that adult neural stem cells bear molecular markers that suggested that they could become neurons. Its absolutely clear that embryonic stem cells can make perfectly good neurons, otherwise there would be no development of the brain, said Stevens. But nobody had demonstrated before that adult stem cells can generate fully functional neurons, beyond just having particular protein markers.

To see whether adult neural stem cells possessed the ability to develop into functional neurons, Gage and his colleagues first isolated stem cells from the hippocampal region of the rat brain and then tagged the cells with fluorescent molecules that made it possible for the researchers to track the stem cells as they developed. The scientists co-cultured these tagged cells along with normal adult neurons on a carpet of supporting cells called astrocytes, which are known to produce chemical signals that trigger neuronal growth.

The normal neurons were necessary to show that our stem-cell-generated neurons were genuine, in the sense that they could incorporate i
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
14-Apr-2002


Page: 1 2 3

Related biology news :

1. Neural stem cells take a step closer to the clinic
2. Neural biology explains ejaculation
3. Neural development in time and space
4. Neural signal that helps wire up brains movement circuit identified
5. Neural stem cells move to damaged areas of brain after injury
6. Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
7. Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease
8. Scientists Discover How Genes Work Together To Control Neural Development
9. Medicinal Leech May Offer Clues To Neural Regeneration
10. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
11. Researchers develop fast track way to discover how cells are regulated

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
(Date:4/5/2017)... -- KEY FINDINGS The global market for ... of 25.76% during the forecast period of 2017-2025. The ... the growth of the stem cell market. ... INSIGHTS The global stem cell market is segmented on ... stem cell market of the product is segmented into ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... (PRWEB) , ... October 09, 2017 , ... ... a four-tiered line of medical marijuana products targeting the needs of consumers who ... packaging of Kindred takes place in Phoenix, Arizona. , As operators of two ...
(Date:10/7/2017)... (PRWEB) , ... October 06, ... ... years’ experience providing advanced instruments and applications consulting for microscopy and surface ... expertise in application consulting, Nanoscience Analytical offers a broad range of contract ...
(Date:10/7/2017)... WALTHAM, Mass. , Oct. 6, 2017 /PRNewswire/ ... pioneering work of three scientists, Jacques Dubochet, ... whose breakthrough developments in cryo-electron microscopy ... this technology within the structural biology community. The ... Scientific. Scientists can now routinely produce highly resolved, ...
(Date:10/6/2017)... D.C. (PRWEB) , ... October 06, 2017 , ... ... will host a lunch discussion and webinar on INSIGhT, the first-ever adaptive clinical ... Principal Investigator, Dana-Farber Cancer Institute. The event is free and open to the ...
Breaking Biology Technology:
Cached News: