HOME >> BIOLOGY >> NEWS
Neural stem cells move to damaged areas of brain after injury

Adult mammalian brain has potential to heal itself, says U-M scientist

BOSTON, Mass. Primitive neural cells in the brains of laboratory rats respond to acute brain injuries by moving to the injured area and attempting to form new neurons, according to University of Michigan neurologist Jack M. Parent, M.D. Understanding how this self-repair mechanism works could someday help physicians reduce brain damage caused by strokes or neurodegenerative diseases.

In a presentation here today at the American Association for the Advancement of Science meeting, Jack M. Parent, M.D., an assistant professor of neurology in the U-M Medical School, described results from a series of his experiments with laboratory rats. Prolonged epileptic seizures or strokes in these rats caused neural precursor cells called neuroblasts cells midway in development between a stem cell and a fully developed neuron to multiply and form neural chains that migrated across the brain to the site of injury.

Whats fascinating is that neuroblasts responded similarly to both types of brain injury, says Parent. Theres some cue in common that activates their development and growth. We dont know what it is, but we are looking for candidate molecules growth factors or neurotrophic factors that stimulate the proliferation and migration of precursor cells.

Parent cautions that, while his results are intriguing, many years of research at the molecular level and in animals will be necessary before human clinical trials could even be considered. Its not enough to stimulate the development of neuroblasts in human brains and hope they do what you want them to do, Parent says. There can be harmful consequences.

Until recently, scientists believed the mammalian adult central nervous system the brain and spinal cord was incapable of generating new neurons from adult stem cells, a process known as neurogenesis. But now scientists know that precursor ce
'"/>

Contact: Sally Pobojewski
pobo@umich.edu
734-615-6912
University of Michigan Health System
18-Feb-2002


Page: 1 2 3

Related biology news :

1. Neural stem cells take a step closer to the clinic
2. Neural biology explains ejaculation
3. Neural development in time and space
4. Neural signal that helps wire up brains movement circuit identified
5. Neural stem cells can develop into functional neurons
6. Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
7. Cultured Neural Stem Cells Reduce Symptoms In Model Of Parkinsons Disease
8. Scientists Discover How Genes Work Together To Control Neural Development
9. Medicinal Leech May Offer Clues To Neural Regeneration
10. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
11. Researchers develop fast track way to discover how cells are regulated

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2017)... a global expert in SoC-based imaging and computing solutions, has developed ... the company,s hybrid codec technology. A demonstration utilizing TeraFaces ® , ... showcased during the upcoming Medtec Japan at Tokyo Big Sight April ... Vegas Convention Center April 24-27. ... Click here for an image of the M820 ...
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), Biometrics, Card-Based ... & Logistics, Government & Public Sector, Utilities / Energy ... Nuclear Power), Industrial, Retail, Business Organisation (BFSI), Hospitality & ... for a definitive report on the $27.9bn Access Control ... ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... , ... They call it the “hairy ball.” It’s an ... a system of linkages and connections so complex and dense that “it looks ... at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics and computational ...
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS announces expanded coverage ... its newest module, US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats ... sealants, synthetic sealants and biologic sealants used in surgical applications. BioMedGPS estimates the ...
(Date:10/11/2017)... LINDA, CA (PRWEB) , ... October 11, 2017 ... ... to upregulate any gene in its endogenous context, enabling overexpression experiments and avoiding ... (CRISPRa) system with small RNA guides is transformative for performing systematic gain-of-function studies. ...
(Date:10/11/2017)... -- VMS BioMarketing, a leading provider of patient support solutions, has ... (CNE) network, which will launch this week. The VMS CNEs ... professionals to enhance the patient care experience by delivering peer-to-peer ... care professionals to help women who have been diagnosed and ... ...
Breaking Biology Technology:
Cached News: