HOME >> BIOLOGY >> NEWS
New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines

By ELIZABETH ZUBRITSKY
UNC-CH News Services

CHAPEL HILL -- Inventions by microbiologists at the University of North Carolina at Chapel Hill and U.S. Army Medical Research Institute of Infectious Diseases have led to creation of AlphaVax, a new company in Durham.

UNC-CH has licensed exclusively to AlphaVax four patents and two applications for patents expected to be issued. The company will develop and market the technology, which has broad applications for vaccines and gene therapy, company officials say. Initial targets include infectious diseases such as HIV -- the virus that causes AIDS -- herpes simplex virus and human papilloma virus.

Dr. Robert E. Johnston, UNC-CH professor of microbiology and immunology and one of the company's founding scientists, said the technology has obvious advantages over other vaccine methods. The new technique is efficient -- delivering large amounts of immunity-provoking substances directly to critical tissues -- and can be used multiple times in the same patient, Johnston said.

The approach grew out of research on the life cycle of the Venezuelan equine encephalitis virus done by Johnston, his UNC-CH colleague Dr. Nancy Davis and the Army institute?s Dr. Jonathan Smith. All AlphaVax scientific founders, the researchers created disarmed versions of the virus, which stimulated the immune system but did not cause disease. They also turned the attenuated virus into a vector -- a delivery vehicle that can be used for many kinds of vaccines. Unlike most vectors, however, this one can be used in the same patient several times.

"Many vectors don't work well if reused because the immune system reacts to them," said Davis, research associate professor of microbiology and immunology. "So far, in our studies in rodents, we haven't run into that problem. We're able to use our vectors for multiple vaccines or booster sh
'"/>

Contact: David L. Williamson
rdtokids@email.unc.edu
919-962-8596
University of North Carolina at Chapel Hill
22-Jan-1998


Page: 1 2

Related biology news :

1. Ferr-Damar wins 2004 Eli Lilly and Company Research Award
2. Open access initiative from the Company of Biologists
3. ESA Corporate Award winner 2001: Weyerhaeuser Company Limited British Columbia Coastal Forest Project Team
4. Warner-Lambert Company gift creates bioinformatics program
5. SFU Spin-Off Company To Research Promising Antibacterial Agents
6. New Company Formed Through Licensing Of Cardiac-Hypertrophy Technology From Texas Institutions
7. Move Over, Protein Kinase C, Youve Got Company: Munc13-1 Is A Novel Diacylglycerol Target That Modulates Neurotransmitter Release
8. Perkin-Elmer, Dr. J. Craig Venter, And TIGR Announce Formation Of New Genomics Company
9. Florida Company Using ORNL Technology For Revolutionary Wheelchair
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Improved nutrition could reduce malaria burden worldwide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at http://www.nxt-id.com ... http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... 22, 2017 , ... For the months of May and ... Spotlight series on “Cell Therapy Regulation” for its regenerative medicine followship. ... unique regulatory challenges of stem cell medical research. , Stem cell clinical trials ...
(Date:6/22/2017)... ... June 22, 2017 , ... Charm Sciences, Inc. is pleased to announce ... determined to be appropriate as a screening test at dairies and farms for raw ... system, and the Charm EZ Lite system. These systems are a combination incubator and ...
(Date:6/20/2017)... SQUARE, Pa. , June 20, 2017  Kibow ... is pleased to announce the issuance of a new ... gout or hyperuricemia by the U.S. Patent and Trademark ... Inc., a winner of the Buzz of Bio award ... , is akin to developing non-drug approaches to chronic ...
(Date:6/19/2017)... ... 2017 , ... As Vice President, Product Services, Mr. Guinter ... support, and client process and SOP development. , Mr. Guinter brings a wealth ... for service providers and top-tier pharmaceuticals, and as an independent consultant supported a ...
Breaking Biology Technology:
Cached News: