HOME >> BIOLOGY >> NEWS
New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines

By ELIZABETH ZUBRITSKY
UNC-CH News Services

CHAPEL HILL -- Inventions by microbiologists at the University of North Carolina at Chapel Hill and U.S. Army Medical Research Institute of Infectious Diseases have led to creation of AlphaVax, a new company in Durham.

UNC-CH has licensed exclusively to AlphaVax four patents and two applications for patents expected to be issued. The company will develop and market the technology, which has broad applications for vaccines and gene therapy, company officials say. Initial targets include infectious diseases such as HIV -- the virus that causes AIDS -- herpes simplex virus and human papilloma virus.

Dr. Robert E. Johnston, UNC-CH professor of microbiology and immunology and one of the company's founding scientists, said the technology has obvious advantages over other vaccine methods. The new technique is efficient -- delivering large amounts of immunity-provoking substances directly to critical tissues -- and can be used multiple times in the same patient, Johnston said.

The approach grew out of research on the life cycle of the Venezuelan equine encephalitis virus done by Johnston, his UNC-CH colleague Dr. Nancy Davis and the Army institute?s Dr. Jonathan Smith. All AlphaVax scientific founders, the researchers created disarmed versions of the virus, which stimulated the immune system but did not cause disease. They also turned the attenuated virus into a vector -- a delivery vehicle that can be used for many kinds of vaccines. Unlike most vectors, however, this one can be used in the same patient several times.

"Many vectors don't work well if reused because the immune system reacts to them," said Davis, research associate professor of microbiology and immunology. "So far, in our studies in rodents, we haven't run into that problem. We're able to use our vectors for multiple vaccines or booster sh
'"/>

Contact: David L. Williamson
rdtokids@email.unc.edu
919-962-8596
University of North Carolina at Chapel Hill
22-Jan-1998


Page: 1 2

Related biology news :

1. Ferr-Damar wins 2004 Eli Lilly and Company Research Award
2. Open access initiative from the Company of Biologists
3. ESA Corporate Award winner 2001: Weyerhaeuser Company Limited British Columbia Coastal Forest Project Team
4. Warner-Lambert Company gift creates bioinformatics program
5. SFU Spin-Off Company To Research Promising Antibacterial Agents
6. New Company Formed Through Licensing Of Cardiac-Hypertrophy Technology From Texas Institutions
7. Move Over, Protein Kinase C, Youve Got Company: Munc13-1 Is A Novel Diacylglycerol Target That Modulates Neurotransmitter Release
8. Perkin-Elmer, Dr. J. Craig Venter, And TIGR Announce Formation Of New Genomics Company
9. Florida Company Using ORNL Technology For Revolutionary Wheelchair
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Improved nutrition could reduce malaria burden worldwide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... ... July 17, 2019 , ... ... practice in the Southeast, and its acclaimed pediatric urologists are among the ... rankings. This annual recognition signifies excellence among the country’s pediatric healthcare landscape. ...
(Date:7/11/2019)... ... July 11, 2019 , ... ... DNA test, today announced a partnership with LiquiTech, a leader in Legionella ... strategic partnership, LiquiTech will integrate Spartan’s innovative environmental DNA testing platform to ...
(Date:7/9/2019)... ... July 08, 2019 , ... On June 27, 2019, ... the innovation behind two Danisco amylase patent applications (EP2859097 and EP2825643). The court ... prior art was without merit and awarded costs to Danisco. , “Testimony ...
Breaking Biology News(10 mins):
(Date:5/14/2019)... TOWNSHIP, N.J. (PRWEB) , ... May 13, 2019 ... ... of custom built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, Medical Device ... new Heliumleak.com company website. The redesigned website aims to improve LDA’s ability to ...
(Date:5/8/2019)... ... May 07, 2019 , ... Standing at 16.2 hands, Atlas is on the large ... a drill team and barrel racing, among other activities. When loping around a corner ... went from being a busy horse to only being able to walk. Fortunately Atlas’ ...
(Date:5/4/2019)... ... May 03, 2019 , ... ... of the Dakila Pesquisas Association, the scientist and ufologist Urandir Fernandes de Oliveira, ... (DF). Urandir detailed the results of some research carried out by the association, ...
(Date:5/2/2019)... Md. (PRWEB) , ... April ... ... to the International Organization for Standardization ISO 9001:2015 standard, REPROCELL USA Inc. ... meet customer requirements. In addition, REPROCELL USA Inc. aims to enhance customer ...
Breaking Biology Technology:
Cached News: