HOME >> BIOLOGY >> NEWS
New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines

By ELIZABETH ZUBRITSKY
UNC-CH News Services

CHAPEL HILL -- Inventions by microbiologists at the University of North Carolina at Chapel Hill and U.S. Army Medical Research Institute of Infectious Diseases have led to creation of AlphaVax, a new company in Durham.

UNC-CH has licensed exclusively to AlphaVax four patents and two applications for patents expected to be issued. The company will develop and market the technology, which has broad applications for vaccines and gene therapy, company officials say. Initial targets include infectious diseases such as HIV -- the virus that causes AIDS -- herpes simplex virus and human papilloma virus.

Dr. Robert E. Johnston, UNC-CH professor of microbiology and immunology and one of the company's founding scientists, said the technology has obvious advantages over other vaccine methods. The new technique is efficient -- delivering large amounts of immunity-provoking substances directly to critical tissues -- and can be used multiple times in the same patient, Johnston said.

The approach grew out of research on the life cycle of the Venezuelan equine encephalitis virus done by Johnston, his UNC-CH colleague Dr. Nancy Davis and the Army institute?s Dr. Jonathan Smith. All AlphaVax scientific founders, the researchers created disarmed versions of the virus, which stimulated the immune system but did not cause disease. They also turned the attenuated virus into a vector -- a delivery vehicle that can be used for many kinds of vaccines. Unlike most vectors, however, this one can be used in the same patient several times.

"Many vectors don't work well if reused because the immune system reacts to them," said Davis, research associate professor of microbiology and immunology. "So far, in our studies in rodents, we haven't run into that problem. We're able to use our vectors for multiple vaccines or booster sh
'"/>

Contact: David L. Williamson
rdtokids@email.unc.edu
919-962-8596
University of North Carolina at Chapel Hill
22-Jan-1998


Page: 1 2

Related biology news :

1. Ferr-Damar wins 2004 Eli Lilly and Company Research Award
2. Open access initiative from the Company of Biologists
3. ESA Corporate Award winner 2001: Weyerhaeuser Company Limited British Columbia Coastal Forest Project Team
4. Warner-Lambert Company gift creates bioinformatics program
5. SFU Spin-Off Company To Research Promising Antibacterial Agents
6. New Company Formed Through Licensing Of Cardiac-Hypertrophy Technology From Texas Institutions
7. Move Over, Protein Kinase C, Youve Got Company: Munc13-1 Is A Novel Diacylglycerol Target That Modulates Neurotransmitter Release
8. Perkin-Elmer, Dr. J. Craig Venter, And TIGR Announce Formation Of New Genomics Company
9. Florida Company Using ORNL Technology For Revolutionary Wheelchair
10. Hopkins Engineering Undergrads Inventions: Power Tools For Double Amputee, Military Surveillance Robot
11. Improved nutrition could reduce malaria burden worldwide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2020)... (PRWEB) , ... January 23, 2020 , ... ... manufacture lifesaving mature red blood cells from stem cells. The red blood ... blood cells, under strictly controlled conditions, for transfusion therapy and replaces the need ...
(Date:1/22/2020)... ... ... Lifecycle Biotechnologies announces the new line of high purity powder chemicals filled into ... process requirements and accurately weighed to 0.001 of a gram. The new line of powder ... Sugars , Carbohydrates , Phosphates , Chelators , ...
(Date:1/8/2020)... ... 2020 , ... R3 Stem Cell, the nation's leader in ... practice network partners. Not only does this save practices considerable monies on the ... themselves are less expensive. , Since the regenerative biologics mostly require dry ice ...
Breaking Biology News(10 mins):
(Date:1/28/2020)... ... January 28, 2020 , ... ... today announced the release of Genedata Expressionist ® 13.5 at the ... of Multi-Attribute Methods (MAM) for characterizing and monitoring the quality of biopharmaceuticals ...
(Date:1/27/2020)... (PRWEB) , ... January 27, 2020 , ... ... announced it has secured financing from strategic investors led by Halma plc ... from existing investors Sonion, TDF Ventures, GII LLC, and WSJ Joshua Fund. A ...
(Date:1/24/2020)... ... 24, 2020 , ... Sierra Instruments, global leader in mass ... ideal for BioPharm OEMS. Sierra also announces RedyCompact™ flow meters ... employ high-precision MEMS (Micro-Electro Mechanical Systems) technology utilizing an advanced, ultra-stable no-drift CMOS ...
(Date:1/22/2020)... ... 21, 2020 , ... Microbial Discovery Group LLC (MDG) is ... and Institutional (I&I) Account Manager. Darrell will focus on servicing MDG’s partners with ... 30 years of sales experience working across multiple different market sectors such as; ...
Breaking Biology Technology:
Cached News: