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New Look At How Cells Move Could Shed Light On Tumor Growth

is important is when you think of tumor cell biology," Huttenlocher said. "A tumor should not be able to invade and metastasize if the individual cells can't move away from each other."

In addition to gaining the ability to stop cell migration, understanding the basic mechanisms could be used, for example, to make desirable cells get into wounds to promote healing, she said.

The December paper was written by Huttenlocher and Alan F. Horwitz, head of the U. of I. department of cell and structural biology; Sean P. Palecek, a Whitaker Foundation Graduate Fellow in Biomedical Engineering at the Massachusetts Institute of Technology; Qui Lu, Wenzli Zhang and Ronald L. Mellgren of the Medical College of Ohio, Toledo; Douglas A. Lauffenburger of the Center for Biomedical Engineering at MIT; and Mark H. Gingsberg of the Scripps Research Institute, La Jolla, Calif. The work was funded by the National Institutes of Health and the Arthritis Foundation.

The Cell Biology paper was written by Huttenlocher, Horwitz and U. of I. graduate students.


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Contact: Jim Barlow, Life Sciences Editor
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University of Illinois at Urbana-Champaign
8-Apr-1998


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