HOME >> BIOLOGY >> NEWS
New Test Opens Window On Corrosive Free-Radical Activity In Individuals

Do antioxidant vitamins protect healthy people from free-radical damage, a process implicated in heart disease, stroke, and cancer, as well as such normal aspects of aging as wrinkled skin? Can some diseases be slowed or reversed with antioxidant compounds?

Perhaps surprisingly, researchers have yet to answer these seemingly straightforward questions, because no technique has existed to easily and directly measure the corrosive effects in the body of these highly reactive types of oxygen nor to assess the effectiveness of any countermeasures that might be taken.

Now, University of Pennsylvania Medical Center scientists have developed a new test to accurately and noninvasively measure free-radical activity in individuals. The method, detailed in the March 31 issue of the Proceedings of the National Academy of Sciences, is both simpler and more sensitive than one developed earlier by the same group. Taken together, the two assays corroborate each other and provide a powerful set of tools to address the role of free radicals in health and disease.

"Do healthy people derive any benefit from taking antioxidants if they have a strong native antioxidant defense?" asks Garret A. FitzGerald, MD, chairman of the department of pharmacology and senior author on the study. "Can antioxidants contribute significantly to the prevention or treatment of disease? This new test will allow us to answer these and other important questions about free-radical activity in individuals."

To date, the evidence linking free radicals to disease and aging -- through a biochemical process analogous to rusting -- and the supposition that antioxidants can limit the deleterious effects of free radicals have been based on statistical studies of groups of people and on test-tube experiments with cells in the laboratory.

These methods, although valuable, give no insight into variation between individuals, some of whom may possess highly
'"/>

Contact: Franklin Hoke
hokef@mail.med.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
31-Mar-1998


Page: 1 2 3

Related biology news :

1. Understanding Molecular Self-Assembly Opens Door For New Sources Of Wood-Like Materials
2. Programmable Cells Open Window Of Opportunity For Gene Therapy
3. X-Ray Concentrator Will Expand Window On High-Energy Universe
4. PEBBLEs Help U-M Scientists Open A Window On Cell Chemistry
5. Female Adolescents Need Calcium During Window Of Opportunity
6. New Materials Remove Corrosive Gas In Coal-Gasification Process
7. Activity of calcium-handling gene appears to prevent cardiac arrhythmias
8. Activity detailed for sirtuins, involved in metabolism, aging, gene expression
9. Activity decrease in exercising older adults linked to decline in resting metabolism
10. UT Southwestern Researchers Find Way To Control Gene Activity, Opening Way For Cancer Drugs
11. Research Findings Suggest Potent, Broad-Spectrum Antiviral Activity For Vertexs Investigational IMPDH Inhibitor VX-497

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Test Opens Window Corrosive Free Radical Activity Individuals

(Date:4/14/2015)... OXFORD, Conn. , April 14, 2015 ... "Company"), a biometric authentication company focused on the growing ... has been nominated for the 2015 New York Design ... The Design100, New York City Design Awards are ... are based on over 2,500 ratings from the marketplace, ...
(Date:4/9/2015)... Synaptics Inc. (NASDAQ: SYNA ), a leading ... will report financial results for the third quarter of ... close of market. The company will host a corresponding ... PT (5:00 p.m. ET), during which management may discuss ... live call, analysts and investors should dial 888-438-5524 (conference ...
(Date:4/2/2015)... BETHESDA, Md. , April 2, 2015 ... Salt Lake City , the American ... election of five new directors to its Board.  Members ... for the ACMG and for forming and advancing its ... the medical genetics profession. "It,s an eventful ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3Synaptics to Report Third Quarter Results on April 23 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
(Date:4/24/2015)... Seoul Semiconductor announced the expansion ... in the lighting market. In recent months, ... technology in emerging markets such as Russia, South ... of applications such as streetlight and area lighting, ... First launched in 2005 the Acrich technology from ...
(Date:4/23/2015)... 23, 2015 Athena San Diego, an ... executive women in San Diego’s technology and life science ... Pinnacle Awards at their Gala on April 30, 2015 ... now at http://athenasd.org/events/ , The Pinnacle Awards ... San Diego vision of fostering networking, risk taking and ...
(Date:4/23/2015)... ON , April 23, 2015 /CNW/ - A ... sustainable packaging award from North America,s ... Brandcheck Competitor Comparison won Silver in the "Sustainability, ... The Brandcheck "Competitor Comparison" is a ... of North American and Global peers. This benchmarking ...
(Date:4/23/2015)... 2015 Six startups from Russia ... 4-17 as part of the U.S.-Russia Innovation Corridor ... of biotechnology startups to participate in the program ... and the University of Maryland (UMD) signed a ... respective universities in the biomedical industry in 2013. ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 3U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 4
Cached News: