HOME >> BIOLOGY >> NEWS
New Test Opens Window On Corrosive Free-Radical Activity In Individuals

Do antioxidant vitamins protect healthy people from free-radical damage, a process implicated in heart disease, stroke, and cancer, as well as such normal aspects of aging as wrinkled skin? Can some diseases be slowed or reversed with antioxidant compounds?

Perhaps surprisingly, researchers have yet to answer these seemingly straightforward questions, because no technique has existed to easily and directly measure the corrosive effects in the body of these highly reactive types of oxygen nor to assess the effectiveness of any countermeasures that might be taken.

Now, University of Pennsylvania Medical Center scientists have developed a new test to accurately and noninvasively measure free-radical activity in individuals. The method, detailed in the March 31 issue of the Proceedings of the National Academy of Sciences, is both simpler and more sensitive than one developed earlier by the same group. Taken together, the two assays corroborate each other and provide a powerful set of tools to address the role of free radicals in health and disease.

"Do healthy people derive any benefit from taking antioxidants if they have a strong native antioxidant defense?" asks Garret A. FitzGerald, MD, chairman of the department of pharmacology and senior author on the study. "Can antioxidants contribute significantly to the prevention or treatment of disease? This new test will allow us to answer these and other important questions about free-radical activity in individuals."

To date, the evidence linking free radicals to disease and aging -- through a biochemical process analogous to rusting -- and the supposition that antioxidants can limit the deleterious effects of free radicals have been based on statistical studies of groups of people and on test-tube experiments with cells in the laboratory.

These methods, although valuable, give no insight into variation between individuals, some of whom may possess highly
'"/>

Contact: Franklin Hoke
hokef@mail.med.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
31-Mar-1998


Page: 1 2 3

Related biology news :

1. Understanding Molecular Self-Assembly Opens Door For New Sources Of Wood-Like Materials
2. Programmable Cells Open Window Of Opportunity For Gene Therapy
3. X-Ray Concentrator Will Expand Window On High-Energy Universe
4. PEBBLEs Help U-M Scientists Open A Window On Cell Chemistry
5. Female Adolescents Need Calcium During Window Of Opportunity
6. New Materials Remove Corrosive Gas In Coal-Gasification Process
7. Activity of calcium-handling gene appears to prevent cardiac arrhythmias
8. Activity detailed for sirtuins, involved in metabolism, aging, gene expression
9. Activity decrease in exercising older adults linked to decline in resting metabolism
10. UT Southwestern Researchers Find Way To Control Gene Activity, Opening Way For Cancer Drugs
11. Research Findings Suggest Potent, Broad-Spectrum Antiviral Activity For Vertexs Investigational IMPDH Inhibitor VX-497

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... , June 22, 2016  The American College of Medical ... Show Executive Magazine as one of the fastest-growing trade ... 25-27 at the Bellagio in Las Vegas ... highest percentage of growth in each of the following categories: ... companies and number of attendees. The 2015 ACMG Annual Meeting ...
(Date:6/22/2016)... , June 22, 2016   ... management and verification solutions, has partnered with ... software solutions for Visitor Management, Self-Service Kiosks ... provides products that add functional enhancements to ... provides corporations and venues with an automated ...
(Date:6/22/2016)... On Monday, the Department of Homeland Security ... solutions for the Biometric Exit Program. The Request for ... (CBP), explains that CBP intends to add biometrics to ... United States , in order to deter visa ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... on what they believe could be a new and helpful biomarker for malignant ... Click here to read it now. , Biomarkers are components in ...
(Date:6/27/2016)... ... 2016 , ... Parallel 6 , the leading software as a service ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication ... , Using the CONSULT module, patients and physicians can schedule a face to face ...
(Date:6/27/2016)... ... June 27, 2016 , ... Newly created ... services and solutions to the healthcare market. The company's primary focus is on ... sales and marketing strategies that are necessary to help companies efficiently bring their ...
(Date:6/27/2016)... Hill, N.C. (PRWEB) , ... June 27, 2016 ... ... U.S. commercial operations for Amgen, will join the faculty of the University ... serve as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a ...
Breaking Biology Technology:
Cached News: