HOME >> BIOLOGY >> NEWS
New amino acid discovered; Fundamental building block of life

One research group, led by Joseph A. Krzycki, an associate professor of microbiology, had been working for several years with a particular strain of microbe, Methanosarcina barkeri. This organism, a member of the recently identified domain Archaea, is able to convert monomethylamine, dimethylamine and trimethylamine into this greenhouse gas.

Krzycki's research group had isolated specific proteins related to the process in 1995 and, two years later, they had isolated and sequenced one of the genes responsible. Then in 1998, they published a paper showing that the gene had a component called an in-frame amber codon that behaved unusually.

Codons are three-letter "words" identifying the bases DNA uses to specify particular amino acids as building blocks of proteins. Normally, codons signal the start of a protein, its end or a particular amino acid used to construct it. Surprisingly, the codon Krzycki's team identified should have signaled a stop to protein building but it did not.

"Joe and his colleagues found this happening in genes important for all three of the methylamine compounds - something that wasn't supposed to happen," explained Michael Chan, an associate professor of biochemistry and chemistry at Ohio State. Chan led the second research team that identified and determined the structure of the amino acid.

The realization of the codon's odd behavior suggested the possibility of
'"/>

Contact: Joseph A. Krzycki
Krzycki.1@osu.edu
614-292-1578
Ohio State University
23-May-2002


Page: 1 2 3 4

Related biology news :

1. 22nd amino acid synthesized and added to genetic code of e. coli bacteria
2. 22-amino acid bacterium created by Scripps scientists
3. Extraterrestrial enigma: missing amino acids in meteorites
4. Scientists at TSRI create new strain of yeast with 21-amino acid genetic code
5. Research shows high doses of acetaminophen clear rapidly and consistently from bloodstream
6. Expanding the genetic code--TSRI scientists synthesize 21-amino-acid bacterium
7. UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure
8. Understanding acetaminophen poisoning
9. Acetaminophen may protect against heart damage according to Rutgers research
10. Moving gene in plant results in increased production of amino acid
11. Scientists probing the origins of life develop method of making novel proteins using a 21st amino acid

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/8/2019)... NEW HOPE, Pa. (PRWEB) , ... May 08, ... ... marketing research firm, announced today that business professional Carol S. Mann has agreed ... joined the company as President and Chief Operating Officer, effective immediately. They will ...
(Date:5/7/2019)... ... May 07, 2019 , ... Landsec and ... test in the UK. , In May, Landsec will undertake trials using Spartan’s ... minutes, enabling operators to take corrective action within hours instead of weeks. ...
(Date:5/2/2019)... JOLLA, Calif. (PRWEB) , ... May 01, 2019 ... ... genomic tests that give families insight into their future children, announces a new ... DNA ” in the journal of Pregnancy and Child Health. Previous studies had ...
Breaking Biology News(10 mins):
(Date:5/2/2019)... ... April 30, 2019 , ... By ... USA Inc. has demonstrated its ability to provide various services and products ... enhance customer satisfaction through the effective implementation of its quality management system, ...
(Date:5/2/2019)... ... ... Stay on top of current hot topics through free webinars presented by leading experts ... so be sure to register today to save your place! Participate in the discussion ... upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology Clinical Trials – The ...
(Date:5/2/2019)... , ... May 02, 2019 , ... ... clinic in the greater Boston area. Gone are the days of painful hair ... iX Robotic Hair Restoration System is the only robotic intelligent solution to offer ...
(Date:4/25/2019)... (PRWEB) , ... April 24, 2019 , ... ... Virtual Agents for sales and service organizations, today announced global availability of ... software providers and enterprises of all sizes to harness the power of ...
Breaking Biology Technology:
Cached News: