HOME >> BIOLOGY >> NEWS
New amino acid discovered; Fundamental building block of life

One research group, led by Joseph A. Krzycki, an associate professor of microbiology, had been working for several years with a particular strain of microbe, Methanosarcina barkeri. This organism, a member of the recently identified domain Archaea, is able to convert monomethylamine, dimethylamine and trimethylamine into this greenhouse gas.

Krzycki's research group had isolated specific proteins related to the process in 1995 and, two years later, they had isolated and sequenced one of the genes responsible. Then in 1998, they published a paper showing that the gene had a component called an in-frame amber codon that behaved unusually.

Codons are three-letter "words" identifying the bases DNA uses to specify particular amino acids as building blocks of proteins. Normally, codons signal the start of a protein, its end or a particular amino acid used to construct it. Surprisingly, the codon Krzycki's team identified should have signaled a stop to protein building but it did not.

"Joe and his colleagues found this happening in genes important for all three of the methylamine compounds - something that wasn't supposed to happen," explained Michael Chan, an associate professor of biochemistry and chemistry at Ohio State. Chan led the second research team that identified and determined the structure of the amino acid.

The realization of the codon's odd behavior suggested the possibility of
'"/>

Contact: Joseph A. Krzycki
Krzycki.1@osu.edu
614-292-1578
Ohio State University
23-May-2002


Page: 1 2 3 4

Related biology news :

1. 22nd amino acid synthesized and added to genetic code of e. coli bacteria
2. 22-amino acid bacterium created by Scripps scientists
3. Extraterrestrial enigma: missing amino acids in meteorites
4. Scientists at TSRI create new strain of yeast with 21-amino acid genetic code
5. Research shows high doses of acetaminophen clear rapidly and consistently from bloodstream
6. Expanding the genetic code--TSRI scientists synthesize 21-amino-acid bacterium
7. UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure
8. Understanding acetaminophen poisoning
9. Acetaminophen may protect against heart damage according to Rutgers research
10. Moving gene in plant results in increased production of amino acid
11. Scientists probing the origins of life develop method of making novel proteins using a 21st amino acid

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/23/2018)... ... November 23, 2018 , ... uBiome, the leader in ... the G. Oppenheimer Center for Neurobiology of Stress and Resilience, to its Medical ... world, Dr. Mayer will bring to uBiome his expertise on the connections between ...
(Date:11/20/2018)... ... November 19, 2018 , ... ... tools, drug development, agriculture, human clinical therapeutics, and animal and disease model), by ... (drug compound and target screening, and agriculture and industrial use), by Patent Activities ...
(Date:11/20/2018)... ... November 20, 2018 , ... Thanks to its long-standing expertise in ID ... ID reader market, as the company now proposes a full range of readers able ... ID reader range can be used by professionals either in a fixed location or ...
Breaking Biology News(10 mins):
(Date:12/5/2018)... ... ... The incredible life story of former refugee and LG Sonic CEO Yousef ... the European Commissioner for Research and Innovation. , In his November 27th speech ... spoke at length of Yousef’s life and journey, citing the man who convinced him ...
(Date:11/29/2018)... LEHI, Utah (PRWEB) , ... November 29, 2018 , ... ... round was led by Kickstart Seed Fund, with participation from existing investor and board ... Investors and Davis Smith of Cotopaxi. The additional funding will enable the company to ...
(Date:11/26/2018)... ... November 26, 2018 , ... USARAD Holdings Inc., the ... Venture Partners (Virtual Radiologic founders) among other healthcare investors exhibits at the Radiological ... Place in Chicago. The company is proud to announce a 10 year anniversary ...
(Date:11/20/2018)... ... November 20, 2018 , ... Each year Forbes receives thousands ... list which highlights outstanding performance by individuals under 30 years of age. The Forbes ... fields from Sports and Entertainment to Venture Capital and Science. , In 2017, ...
Breaking Biology Technology:
Cached News: