HOME >> BIOLOGY >> NEWS
New findings represent the first aerobic capacity QTLs identified in genetic models

The Study

Researchers believe that genes for both inherited aerobic capacity and the adaptational response to aerobic exercise must be resolved in order to understand the role that aerobic capacity plays in defining the entire relationship between health and disease. Accordingly, Lauren Gerard Koch, Justin A. Ways, George T. Cicila, Michael R. Garrett, and Steven L. Britton, all from the Functional Genomics Laboratory, Department of Physiology and Molecular Medicine, Medical College of Ohio, Toledo, Ohio, have conducted a study entitled A Genome Scan for Loci Associated with Aerobic Running Capacity in Rats. Their long-term goal is to use these inbred model systems to identify genes, proteins, and intermediate phenotypes that collectively cause differences between low and high aerobic capacity.

The researchers will present their findings in full during the American Physiological Societys (APS) annual meeting, part of the "Experimental Biology 2002 conference. More than 12,000 will attend the conference being held at the Ernest N. Morial Convention Center, New Orleans, LA from April 20-24, 2002.

Methodology

Their scan for intrinsic aerobic exercise capacity quantitative trait loci (QTLs) in rats was based on 210 polymorphic microsatellite markers and an F2 intercross population (n = 224) derived from Copenhagen (COP) and DA strains. (In previous experiments, the researchers tested maximal treadmill running capacity in a panel of eleven different inbred rat strains to evaluate the genetic variance that exists for intrinsic (untrained) aerobic capacity. At the extremes, DA inbred rats showed the highest capacity and ran 810 meters to exhaustion whereas Copenhagen (COP) rats were the lowest performers and became exhausted by 300 meters. This wide difference in phenotypic values suggested that the COP and DA rats could serve as parental strains for a genetic cross to test for an association between allelic variation (alter
'"/>

Contact: Donna Krupa
703-967-2751
American Physiological Society
22-Apr-2002


Page: 1 2 3 4

Related biology news :

1. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
2. Virginia Tech researchers to release findings on Smith River Project
3. New HIV findings
4. Stanford researchers findings may shed light on common, deadly birth defect
5. Briggs takes to the molecular level Darwins findings on plants sensing the direction of light
6. Latest findings on PCBs to be subject of June workshop at Illinois
7. Chlamydia in men now also linked to infertility new findings
8. New MS research shows remarkable findings
9. Scientists findings may lead to better understanding of how that sleep develops, matures
10. New findings are a window into the late stages of Lou Gehrigs disease
11. New findings bring mixed blessings to those looking to combat jet lag

Post Your Comments:
(Date:5/27/2015)...   Codonics (codonics.com), a global ... documentation solutions and Omnicell  (omnicell.com), a ... is pleased to announce their state of ... System® (SLS), an award-winning FDA class 2 ... Anesthesia Workstation, helps prevent medication errors, streamlines ...
(Date:5/22/2015)... 2015 According to a new ... 3D, Thermal, Emotion, Forensic), by Software (Middleware, Databases), by Hardware ... Consumer and Home) - Global Forecast to 2020", published ... Billion in 2015 to $6.19 Billion by 2020, at ... market data Tables and   43 Figures spread through ...
(Date:5/20/2015)... May 20, 2015 NXT-ID, Inc. (NASDAQ: ... wholly owned subsidiary, 3D-ID LLC, a company engaged in ... for the biometrics technology portion of the recently awarded ... the Department of the Army. 3D-ID LLC ... for government, law enforcement and security agencies. ...
Breaking Biology News(10 mins):Codonics and Omnicell Expand Partnership 2Codonics and Omnicell Expand Partnership 3Codonics and Omnicell Expand Partnership 4Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3
(Date:5/29/2015)... 29, 2015 The changing healthcare landscape ... involving clinical development, regulatory compliance and market education. ... Medical Affairs has faced many challenges in creating ... And while its importance is recognized internally, Medical ... strong performance metrics to demonstrate the value of ...
(Date:5/29/2015)... HILL, N.C. , May 29, 2015 ... explosion in the availability of Big Data that can ... challenges that come with utilizing Big Data have caused ... slower than other industries. According to ... 53% of participants already have a Big Data team ...
(Date:5/29/2015)... -- BerGenBio AS ("BerGenBio" or the "Company"), ... on the latest data on BGB324, the Company,s first-in-class, ... kinase, and BGB10C9, an Axl function-blocking monoclonal antibody in ... with the 2015 American Society of Clinical Oncology (ASCO) ... 29 - June 2, 2015. The abstract ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 ... multi-drug-resistant organisms (MDROs), announced that initial feasibility data ... bacterial detection and susceptibility testing from positive blood ... on May 31, 2015 in New Orleans, LA. ... of molecular diagnostics that can quickly detect bacteria ...
Breaking Biology Technology:Creating an Effective Pharmaceutical Medical Affairs Group with Global Capabilities 2New Study Details Current & Future Big Data Trends Across Medical Affairs Functions 2BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 2BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 3Data Highlighting GeneWEAVE’s Smarticles™ Technology to be Presented at the 115th General Meeting of the American Society for Microbiology (asm2015) 2Data Highlighting GeneWEAVE’s Smarticles™ Technology to be Presented at the 115th General Meeting of the American Society for Microbiology (asm2015) 3
Cached News: