HOME >> BIOLOGY >> NEWS
New findings represent the first aerobic capacity QTLs identified in genetic models

The Study

Researchers believe that genes for both inherited aerobic capacity and the adaptational response to aerobic exercise must be resolved in order to understand the role that aerobic capacity plays in defining the entire relationship between health and disease. Accordingly, Lauren Gerard Koch, Justin A. Ways, George T. Cicila, Michael R. Garrett, and Steven L. Britton, all from the Functional Genomics Laboratory, Department of Physiology and Molecular Medicine, Medical College of Ohio, Toledo, Ohio, have conducted a study entitled A Genome Scan for Loci Associated with Aerobic Running Capacity in Rats. Their long-term goal is to use these inbred model systems to identify genes, proteins, and intermediate phenotypes that collectively cause differences between low and high aerobic capacity.

The researchers will present their findings in full during the American Physiological Societys (APS) annual meeting, part of the "Experimental Biology 2002 conference. More than 12,000 will attend the conference being held at the Ernest N. Morial Convention Center, New Orleans, LA from April 20-24, 2002.

Methodology

Their scan for intrinsic aerobic exercise capacity quantitative trait loci (QTLs) in rats was based on 210 polymorphic microsatellite markers and an F2 intercross population (n = 224) derived from Copenhagen (COP) and DA strains. (In previous experiments, the researchers tested maximal treadmill running capacity in a panel of eleven different inbred rat strains to evaluate the genetic variance that exists for intrinsic (untrained) aerobic capacity. At the extremes, DA inbred rats showed the highest capacity and ran 810 meters to exhaustion whereas Copenhagen (COP) rats were the lowest performers and became exhausted by 300 meters. This wide difference in phenotypic values suggested that the COP and DA rats could serve as parental strains for a genetic cross to test for an association between allelic variation (alter
'"/>

Contact: Donna Krupa
703-967-2751
American Physiological Society
22-Apr-2002


Page: 1 2 3 4

Related biology news :

1. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
2. Virginia Tech researchers to release findings on Smith River Project
3. New HIV findings
4. Stanford researchers findings may shed light on common, deadly birth defect
5. Briggs takes to the molecular level Darwins findings on plants sensing the direction of light
6. Latest findings on PCBs to be subject of June workshop at Illinois
7. Chlamydia in men now also linked to infertility new findings
8. New MS research shows remarkable findings
9. Scientists findings may lead to better understanding of how that sleep develops, matures
10. New findings are a window into the late stages of Lou Gehrigs disease
11. New findings bring mixed blessings to those looking to combat jet lag

Post Your Comments:
(Date:4/17/2014)... ALBUQUERQUE, N.M. A credit-card-sized anthrax detection cartridge developed ... small business makes testing safer, easier, faster and cheaper. ... causes anthrax, is commonly found in soils all over ... illness in both humans and animals. The bacteria can ... to B. anthracis may occur through skin ...
(Date:4/17/2014)... bone marrow need to produce hydrogen sulfide in order ... a new study from the Center for Craniofacial Molecular ... USC. , Professor Songtao Shi, principal investigator on the ... the cells governs the flow of calcium ions. The ... results in osteogenesis, or the creation of new bone ...
(Date:4/17/2014)... and pathogens that devastate honeybees in Europe, Asia and ... do not appear to be impacting native honeybee populations ... researchers., The invasive pests include including Nosema microsporidia ... honeybees appear to be resilient to these invasive pests, ... control pests in Europe, Asia and the United States ...
Breaking Biology News(10 mins):Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3
(Date:1/15/2014)... This webinar will focus on EMA and ... in biosimilars. , Regulatory frameworks are evolving many countries ... the complex nature of biopharmaceuticals makes the demonstration of ... challenging. Based on the specific aspects of biosimilar drug ...
(Date:1/15/2014)... Two champions of science, technology, engineering, ... an annual competition for middle and high school students ... STEM study. The competition presents students with real-world problems ... Aptitude, Mathematics, and Sciences is a program administered ...
(Date:1/15/2014)... Scottsdale, Arizona (PRWEB) January 15, 2014 ... growth for Scottsdale’s Brain State Technologies®. They saw continued ... University Medical Center who were awarded a $1 million ... papers published in “Brain and Behavior” a peer reviewed ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
Breaking Biology Technology:Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
Cached News: