HOME >> BIOLOGY >> NEWS
New findings represent the first aerobic capacity QTLs identified in genetic models

The Study

Researchers believe that genes for both inherited aerobic capacity and the adaptational response to aerobic exercise must be resolved in order to understand the role that aerobic capacity plays in defining the entire relationship between health and disease. Accordingly, Lauren Gerard Koch, Justin A. Ways, George T. Cicila, Michael R. Garrett, and Steven L. Britton, all from the Functional Genomics Laboratory, Department of Physiology and Molecular Medicine, Medical College of Ohio, Toledo, Ohio, have conducted a study entitled A Genome Scan for Loci Associated with Aerobic Running Capacity in Rats. Their long-term goal is to use these inbred model systems to identify genes, proteins, and intermediate phenotypes that collectively cause differences between low and high aerobic capacity.

The researchers will present their findings in full during the American Physiological Societys (APS) annual meeting, part of the "Experimental Biology 2002 conference. More than 12,000 will attend the conference being held at the Ernest N. Morial Convention Center, New Orleans, LA from April 20-24, 2002.

Methodology

Their scan for intrinsic aerobic exercise capacity quantitative trait loci (QTLs) in rats was based on 210 polymorphic microsatellite markers and an F2 intercross population (n = 224) derived from Copenhagen (COP) and DA strains. (In previous experiments, the researchers tested maximal treadmill running capacity in a panel of eleven different inbred rat strains to evaluate the genetic variance that exists for intrinsic (untrained) aerobic capacity. At the extremes, DA inbred rats showed the highest capacity and ran 810 meters to exhaustion whereas Copenhagen (COP) rats were the lowest performers and became exhausted by 300 meters. This wide difference in phenotypic values suggested that the COP and DA rats could serve as parental strains for a genetic cross to test for an association between allelic variation (alter
'"/>

Contact: Donna Krupa
703-967-2751
American Physiological Society
22-Apr-2002


Page: 1 2 3 4

Related biology news :

1. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
2. Virginia Tech researchers to release findings on Smith River Project
3. New HIV findings
4. Stanford researchers findings may shed light on common, deadly birth defect
5. Briggs takes to the molecular level Darwins findings on plants sensing the direction of light
6. Latest findings on PCBs to be subject of June workshop at Illinois
7. Chlamydia in men now also linked to infertility new findings
8. New MS research shows remarkable findings
9. Scientists findings may lead to better understanding of how that sleep develops, matures
10. New findings are a window into the late stages of Lou Gehrigs disease
11. New findings bring mixed blessings to those looking to combat jet lag

Post Your Comments:
(Date:4/10/2015)... Research and Markets ( http://www.researchandmarkets.com/research/cjk4gb/security ) has ... - NEC" report to their offering. ... to supply a range of IT security management and ... on the development of a Big Data and cloud ... Asia-Pacific region is a core ...
(Date:4/6/2015)... , Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/143028 for MINIATURE, MULTI-PURPOSE ... TRANSFER  NXT-ID introduces a new revolutionary ... patent surrounds the use of miniature antenna modules ...
(Date:4/2/2015)... , April 2, 2015 ... Q1 2015 attributed to somewhat higher than 125 MSEK. ... the year-end report 2014 that revenues for Q1 2015 ... the company reported for Q4 2014. The operating result ... be negative. The complete interim report will as previously ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4Fingerprint Cards Revises Revenues for Q1 2015 2
(Date:5/1/2015)... -- Investor-Edge has initiated coverage on ... GENE ), Agilent Technologies Inc. (NYSE: A ... ), Sequenom Inc. (NASDAQ: SQNM ), and ... report on Genetic Technologies can be accessed at ... the NASDAQ Composite ended at 4,941.42, down 1.64%, ...
(Date:5/1/2015)... , May 1, 2015 ... "Antibody Production Market by Product (Equipment, Consumables), by Type ... Companies, Diagnostic Labs, Research Institutes) - Analysis & ... report studies the global Antibody Production Market for ... market is expected to reach $2.572 Billion by ...
(Date:4/30/2015)... 2015 Spirax Sarco, the leader in ... to announce that for the first time in the ... of a Queen’s Award for Innovation – the UK’s ... manufacture of a unique flowmeter. , The Spirax Sarco ... traditional steam flow measurement. The device provides reliable, ...
(Date:4/30/2015)... 2015   Tamir Biotechnology , a leading developer ... its Ebola antiviral therapy program. Clinical ... currently being evaluated and considered by a number of ... During the first quarter of 2015, the company participated ... The Evaluation of Potential Treatments and Vaccines For Ebola ...
Breaking Biology Technology:Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5Antibody Production Market worth $2.572 Billion by 2019 2Antibody Production Market worth $2.572 Billion by 2019 3Antibody Production Market worth $2.572 Billion by 2019 4Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 2Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 3Tamir Biotechnology Provides Update on TMR004 Development Against Mutating Ebola 4
Cached News: