HOME >> BIOLOGY >> NEWS
New genetic 'fishing net' harvests elusive autism gene

DURHAM, N.C. -- Duke University Medical Center researchers have developed a new statistical genetic "fishing net" that they have cast into a sea of complex genetic data on autistic children to harvest an elusive autism gene.

Moreover, the researchers said that the success of the approach will be broadly applicable to studying genetic risk factors for other complex genetic diseases, such as hypertension, diabetes and multiple sclerosis.

In this case, the gene, which encodes part of a brain neurotransmitter docking station called the gamma-Aminobutyric Acid Receptor beta3-subunit (GABRB3), has been implicated in autism previously, but never positively linked to the disease. Their findings will be published in the March 2003 issue of the American Journal of Human Genetics and is now available on the Web at http://www.journals.uchicago.edu/AJHG/journal/issues/v72n3/024607/024607.html.

"Many research groups have been actively looking for genetic risk factors that can lead to autism, but without much success," said Margaret Pericak-Vance, Ph.D., director of the Duke Center for Human Genetics and lead investigator of the study.

Autism is the common term that encompasses an overlapping group of complex developmental disorders that are diagnosed in about one in 1,000 children under the age of 3. Each autistic child has a unique set of characteristics that affect his or her behavior, communication skills and ability to interact with others. It is the very diverse, complex nature of autism that has made it so difficult to locate distinct genetic risk factors, said Pericak-Vance.

After several genetic studies turned up only a few vague genetic clues, the research team decided a new approach was needed. Pericak-Vance hypothesized that grouping patients with similar traits together statistically might enhance the scientist
'"/>

Contact: Richard Puff
richard.puff@duke.edu
919-684-4148
Duke University Medical Center
6-Feb-2003


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Rare childhood genetic syndrome identified
3. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
4. Scientists decipher genetic code of biothreat pathogen
5. Chemical genetics identifies SARS inhibitors
6. 22nd amino acid synthesized and added to genetic code of e. coli bacteria
7. The impact of genetic variations on the treatment of early rheumatoid arthritis
8. Adaptive changes in the genome may provide insight into the genetics of complex disease
9. New genetic hypothesis for the cause of autism
10. Fossils reveal direct link between global warming and genetic diversity in wildlife
11. A genetic disorder yields insight into genes and cognition

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New genetic fishing net harvests elusive autism gene

(Date:7/7/2015)... , June 30, 2015 ... announced the addition of the "Capacitive Fingerprint ... To this date, fingerprint sensing technology ... and fingerprint sensors are well developed. This patent ... technology. The domain of capacitive fingerprint ...
(Date:7/7/2015)... Calif. , July 7, 2015  Based ... market, Frost & Sullivan recognizes Credence ID, LLC ... Entrepreneurial Company of the Year Award. Credence ... to aid in its mission of offering enrollment ... populations globally. As Credence ID was formed by ...
(Date:7/7/2015)... July 7, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... growing mobile commerce market announces a revised version of one of ... commercial will air on CNBC in New York ... and San Francisco metro areas.    ... on Wocket,s ability to replace all the cards in your wallet ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3
(Date:7/7/2015)... ... July 07, 2015 , ... 4MD Medical , the leading online ... exclusive scholarship opportunity for women across the country to earn $2,000 toward academic funding. ... their education,” said Rochelle Schwartz, Founder of 4MD Medical and successful business woman that ...
(Date:7/7/2015)... 7, 2015  SME,s Advanced Manufacturing Media is proud ... 30" issue, celebrating young men and women who have ... July issue of Manufacturing Engineering ... for their accomplishments. Among the standouts: Christopher Tyler ... on optimizing the topology of flapping wing vehicles; ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... in the biometrical area. What began as a conference for European Statistical Programmers, ... various functions in the biometrical area. Statistical Programmers, Data Managers and Biostatisticians all ...
(Date:7/6/2015)... Washington, USA, and CARDIFF, UK (PRWEB) , ... ... ... used in ophthalmology and other medical fields holds potential to reveal how blood ... treatments and reduce stroke-induced damage to the brain. , A new article published ...
Breaking Biology Technology:4MD Medical Announces $2,000 Scholarship Opportunity in Conjunction with American Business Women’s Association (ABWA) 24MD Medical Announces $2,000 Scholarship Opportunity in Conjunction with American Business Women’s Association (ABWA) 3SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 2SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 3SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 4SME's Advanced Manufacturing Media Recognizes "30 Under 30" Future Leaders of Manufacturing 5PhUSE Delighted to Welcome Member Number 5.000 2Reducing Stroke Damage May be Next Application for OCT Technology Now Widely Used in Eye and Vision Healthcare 2Reducing Stroke Damage May be Next Application for OCT Technology Now Widely Used in Eye and Vision Healthcare 3
Cached News: