HOME >> BIOLOGY >> NEWS
New imaging technique developed to identify breast cancer

Researchers at Johns Hopkins have for the first time used a chemical marker detected by proton magnetic resonance spectroscopic imaging (MRSI) to successfully diagnose breast cancer. The diagnostic technique produces pictures of choline within breast tumors.

In the study, researchers from the Russell H. Morgan Department of Radiology and Radiological Science at Hopkins demonstrated that choline signals analyzed by MRI were significantly elevated in malignant tumors in 15 of 18 patients studied. Three of the cases could not be included because of technical failures such as patient movement or computer failure during the scanning procedure.

The results are published in the December-January issue of the Journal of Magnetic Resonance Imaging.

Scientists have long known that cancers contain elevated levels of choline, a product of membrane synthesis, but the Hopkins study is believed to be the first to demonstrate its value in accurately identifying breast tumors.

MRSI of the breast does not appear likely to be cost-effective as a routine screening tool for breast cancer, but may prove to be a viable, noninvasive alternative to biopsy in cases with positive mammography or clinical breast exam results, says Michael A. Jacobs, Ph.D., the lead researcher for the Hopkins study. "What MRSI does provide is information about the molecular environment of breast tumors, which also may be useful in designing therapeutic interventions for patients."

Proton magnetic resonance imaging uses the water content in tissue to produce images by measuring signals emitted after subjecting the tissue to high magnetic fields, but provides no information on the chemical or molecular aspects of the tissue being imaged. Combining proton MRI with spectroscopy allows the scientists to differentiate intracellular components of the cell and signals emitted by certain biochemicals, such as choline.

In the study, 15 patients who had been referred
'"/>

Contact: Gary Stephenson
gstephenson@jhmi.edu
410-955-5384
Johns Hopkins Medical Institutions
1-Mar-2004


Page: 1 2

Related biology news :

1. New imaging technology at Joslin shown to detect early signs of type 1 diabetes
2. Trojan Horses, xenon imaging and remote controlled genes
3. Small animal imaging gives cancer clues
4. Computer imaging of Archeopteryx skull suggests this dinosaur-bird link could fly
5. Innovative efforts target epigenetics, molecular imaging
6. Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood
7. Whole body imaging allows better understanding of the immune system
8. 3-D micro-imaging technology licensed to Carl Zeiss Jena
9. SPECT imaging shows promise for accurate, early diagnosis of Alzheimers
10. Carnegie Mellon enhances Quantum Dot Corp. technology for long-term, live-animal imaging
11. Combining various magnetic resonance imaging techniques may help improve breast cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New imaging technique developed identify breast cancer

(Date:11/18/2014)... WASHINGTON , Nov. 18, 2014  The ... Security Industry Association today jointly announce the formation ... and release of its Identity and Biometric ... (Framework). The Framework received official support from BORDERPOL, ... governments to improve and provide expertise regarding border ...
(Date:11/18/2014)... Md. , Nov. 17, 2014 The Parenteral ... and U.S. regulatory agencies will speak and at least seven ... Metrics Conference at the Omni Shoreham Hotel in ... pleased once again to have significant support from the regulatory ... Europe in our effort to help ...
(Date:11/15/2014)... we may still be a few years away from the ... gain instant access to all that ailed his patients, mobile ... for monitoring and measuring our health are cropping up in ... tad Orwellian to some, but a new survey suggests that ... into their healthcare regime. These are some of ...
Breaking Biology News(10 mins):Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4
(Date:11/18/2014)... November 17, 2014 Athena Signature Series: Turning ... Dr. Beverly Emerson, a professor in the Regulatory Biology Laboratory ... most recent discovery points to an “off switch” for drug ... and how her local research is making a global impact ... findings and then join host Cheryl K. Goodman, CEO of ...
(Date:11/18/2014)... FL (PRWEB) November 18, 2014 Brothers ... announced the launch of PAWSitively Curing Cancer, Inc ... This new 501(c) (3) non-profit organization is dedicated to ... donated goes directly to the University of Florida ... partner with PAWSitively Curing Cancer as the recipient of ...
(Date:11/18/2014)... INCLINE VILLAGE, Nev. , Nov. 18, 2014 /PRNewswire/ ... ) today announced that in connection with the acquisition ... approximately $42.7 million in connection with the termination of ... the full principal amount outstanding of $40 million, accrued ... October 2013, PDL entered into a structured financing transaction ...
(Date:11/18/2014)... 2014  Novira Therapeutics, Inc., a privately held biopharmaceutical ... hepatitis B virus (HBV) infection, today announced that ... Scientific Advisory Board (SAB).  "We are ... Christian S. Schade , Chief Executive Officer of Novira.  ... will be invaluable to Novira as our lead core ...
Breaking Biology Technology:PAWSitively Curing Cancer, Inc. Launched By Two Children for National Pet Cancer Awareness Month 2PAWSitively Curing Cancer, Inc. Launched By Two Children for National Pet Cancer Awareness Month 3PDL BioPharma Announces Successful Conclusion of Debt Financing Agreement with Durata Therapeutics 2Novira Therapeutics Announces Appointment of Brian F. Daniels, M.D., to its Scientific Advisory Board 2Novira Therapeutics Announces Appointment of Brian F. Daniels, M.D., to its Scientific Advisory Board 3
Cached News: