HOME >> BIOLOGY >> NEWS
New method of identifying and isolating stem cells developed

Researchers at the Howard Hughes Medical Institute at The Rockefeller University have discovered a new method to track and isolate elusive stem cells. The new animal model they developed was successfully tested by isolating and characterizing skin stem cells, but may also be valuable in searching for stem cells that produce the cells of the heart, pancreas or other specific body tissues.

The finding, to appear in the journal Science and reported online in the Dec. 12 issue of Science Express, offers promise for what could be the first broadly adaptable way to find such master cells, which can create tissue as needed and are seen as the foundation for regenerative medicine. Before this finding, the only stem cells that had been isolated and characterized were from blood, nerve cells and embryonic tissue.

In order to avoid accumulating damaging mutations, long-lived stem cells in their natural home (niche) are often "slow cycling," dividing only infrequently. However, upon injury or normal "wear and tear," stem cells are mobilized to leave their niche, divide and replenish the damaged tissue. The study provides a list of more than 150 genetic factors that distinguish the long-lived, "slow cycling" stem cells of the skin from their short-lived, rapidly dividing "daughter cells."

This information will help scientists understand how these mysterious cells are able to replenish both skin epidermis and hair, and what nutrients may help stem cells produce more stem cells in the laboratory. In addition, some of these new genes are likely to serve as markers for these stem cells, making them easier to identify and isolate in the future.

"We now have a much better picture of the traits of mouse skin stem cells, and we can now use these genetic data to examine whether human skin stem cells possess similar traits to the mouse stem cells," says the study's lead investigator, Elaine Fuchs, Ph.D., professor and head of the Laboratory of Mammalian C
'"/>

Contact: Joseph Bonner
bonnerj@rockefeller.edu
212-327-8998
Rockefeller University
11-Dec-2003


Page: 1 2 3 4 5

Related biology news :

1. OHSU researchers discover possible method for early detection, prevention of premature birth
2. Japanese researchers develop novel method of introducing transgenes into animals
3. New screening method turns up potential compound for treating anthrax
4. Radiologists provide safe delivery method for gene therapy
5. New method is first to mimic subtle genetic changes
6. New method for determining age of artifacts fills chronological gap for scientists
7. Proven method of bone analysis may clarify human origins
8. UVa researchers describe method of protecting chromosomes during cell division
9. Computer method identifies potentially active enzymes
10. Risk and food are on the same plate: World food safety experts offer new methods to assess risk
11. Purdue engineers develop quick, inexpensive method to prototype microchips

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/2/2017)... , Feb. 2, 2017   TapImmune, Inc. ... immuno-oncology company specializing in the development of innovative ... treatment of cancer and metastatic disease, announced today ... GMP manufacturing of a second clinical lot of ... folate receptor alpha. The manufactured vaccine product will ...
(Date:1/30/2017)... , Jan. 30, 2017   Invitae Corporation ... growing genetic information companies, today announced that it will ... and provide 2017 guidance on Monday, February 13, 2017, ... that day at 4:45 p.m. Eastern / 1:45 p.m. ... team will briefly review financial results, guidance, and recent ...
(Date:1/24/2017)...  It sounds simple and harmless—an electronic sensor ... signs and alerts parents on their smart phones ... drops. But pediatric experts argue that such devices ... evidence of medical benefits, especially to healthy babies. ... parents of healthy babies, promising peace of mind ...
Breaking Biology News(10 mins):
(Date:2/23/2017)... SAN DIEGO and SAN FRANCISCO ... , a privately-held regenerative medicine company, and Beyond Type ... living with type 1 diabetes, today announced a grant ... develop a functional cure for type 1 and other ... decade, ViaCyte has been developing innovative stem cell-derived cell ...
(Date:2/22/2017)... ... 22, 2017 , ... Kernel , a human intelligence ... (KRS) clinical development program. KRS is a neurotechnology spin-out from the Massachusetts ... applications. The terms of the transaction were not disclosed. , It addition ...
(Date:2/22/2017)... Feb. 22, 2017 Scientists propose in ... organ damage in Gaucher and maybe other lysosomal storage ... lower costs than current therapies. An international ... Center , which also included investigators from the University ... their data Feb. 22. The study was conducted in ...
(Date:2/22/2017)... ... February 22, 2017 , ... LabRoots ... scientists from around the world, is pleased to announce the 2nd annual Precision ... 2017. This premier, online-only conference focused on the development and advancements in precision ...
Breaking Biology Technology:
Cached News: