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New mutant mouse repositories established for biomedical researcher community

Bethesda, MDThe National Center for Research Resources (NCRR) at the National Institutes of Health (NIH) announces the official opening of a Mutant Mouse Regional Resource Centers (MMRRCs) network. This network will function as a one-stop shop for the U.S. biomedical research community to donate and acquire mutant mouse models. The MMRRC network is now accepting genetic mouse strains to its collection and invites investigators who have created such models to donate them to the network for broad dissemination upon request by other investigators who will use them in research of human health, disease, and treatments. It is estimated that there are more than 3,000 strains of mutant mice that have been created by turning on and off particular genes or by inserting foreign genes into the mouse genome.

"When numerous researchers have access to a shared national resource, such as the MMRRC network," says NCRR Director Dr. Judith Vaitukaitis, "the effectiveness of that resource is maximized relative to its monetary cost and scientific impact." She adds, "Shared resources allow scientists to integrate diverse research expertise, rapidly and effectively study emerging health problems, address complex research queries, and pursue unexpected research opportunities."

The MMRRC network currently includes four repository-distribution facilities located at the University of North Carolina at Chapel Hill; the University of California at Davis; Taconic Farms in New York; and Harlan Sprague Dawley, Inc., in collaboration with the University of Missouri.

The MMRRC network is electronically linked through an NCRR-sponsored MMRRC Informatics Coordinating Center (ICC) to function as one facility. The ICC, which is located at The Jackson Laboratory in Bar Harbor, Maine, provides database and other informatics support to the MMRRCs to give the research community a single entry point to the network through the MMRRC Web site at www.mmrrc.org. This site provide
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Contact: Kathy Kaplan
kaplank@ncrr.nih.gov
301-435-0888
NIH/National Center for Research Resources
17-Jul-2001


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