HOME >> BIOLOGY >> NEWS
New national studies show combined hormone replacement therapy boosts stroke, dementia

CHAPEL HILL -- Last March, a multi-center national study made headlines by concluding that taking a combination of the hormones estrogen and progestin did not improve the quality of life for women who are free of menopause-related symptoms but did expose them to a slightly higher risk of heart attacks, strokes and breast cancer.

For that reason, many medical scientists began recommending against the combined therapy in the absence of such symptoms, saying the risks of estrogen plus progestin outweighed the benefits.

The latest findings from Women's Health Initiative studies provide new evidence that the combined hormone therapy significantly boosts the risks of dementia and strokes in postmenopausal women while not improving what scientists call "global cognitive function" -- how the brain works.

"The strength of the findings last year, as well as the new ones, is not only the large number of study participants, but also that they were randomly assigned to receive daily estrogen plus progestin or placebo," said Dr. Gerardo Heiss, professor of epidemiology at the University of North Carolina at Chapel Hill School of Public Health.

The Women's Health Initiative Memory Study (WHIMS), which showed roughly a doubling of dementia among those in the treatment group, involved 4,532 women, while the new stroke investigation involved 16,608.

As a member of its steering committee, Heiss helped design the overall Women's Health Initiative study, which is producing useful data for numerous ancillary studies. He is co-author of the stroke report, whose lead author is Dr. Sylvia Wasserthiel-Smoller of the Albert Einstein College of Medicine. Drs. Sally A. Shumaker and Stephen R. Rapp of Wake Forest University are first authors of the WHIMS dementia and global cognitive function studies, respectively.

"What is new in the WHI paper on stroke is that we now include all the strokes with 5.6 years follow-up, adjudicated by neurologists wi
'"/>

Contact: David Williamson
919-962-8596
University of North Carolina at Chapel Hill
27-May-2003


Page: 1 2 3

Related biology news :

1. Chemical engineering grad students will take notable national awards
2. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
3. USAID, Conservation International & Starbucks launch Conservation Coffee Alliance in Central America
4. ConocoPhillips & Conservation International launch Biodiversity Action Plan in Venezuela
5. Joslin President awarded medal from international diabetes organization
6. A room with a view for the International Space Station: Completion of the cupola observation module
7. Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
8. Women who have donated eggs sought for national study
9. International symposium on nutritional genomics
10. Increasing international insect threat to stored food
11. UCSB professor and director receives two national awards

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2020)... , ... August 25, 2020 , ... Modality Solutions, ... Inc. magazine’s 2020 annual Inc. 5000 list. The list is the most prestigious ranking ... 2019 as well, and for this year’s list, reported three-year revenue growth of 71 ...
(Date:8/21/2020)... ... August 18, 2020 , ... Sentien Biotechnologies, Inc., a ... U.S. Food and Drug Administration (FDA) has approved the company’s Investigational New Drug ... of severe COVID-19. Approval of this IND allows Sentien to initiate a Phase ...
(Date:8/21/2020)... ... August 19, 2020 , ... ... conference and expo uniting life science, data science, informatics and IT leaders goes ... “In this period of uncertainty and change, Bio-IT takes the leadership role of ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... HONG KONG (PRWEB) , ... July 09, 2020 ... ... chemical compound called 1-phenyl-2-thiourea (PTU) is commonly used to suppress pigment formation in ... years, the PolyU research team led by Dr MA has been using the ...
(Date:7/7/2020)... SAN DIEGO (PRWEB) , ... July 06, 2020 , ... ... a new program featuring up to 200 million stem cells. Depending on the patient's ... of seniors in the US will die having some form of Alzheimers dementia, and ...
(Date:7/1/2020)... ... June 29, 2020 , ... ... date growth of 40% in 2020, despite many obstacles created as a result ... to increase revenue for its partnered medical practices and medical manufacturers by expanding ...
(Date:7/1/2020)... ... June 30, 2020 , ... ... data insights, today announced that the launch of a new clinical ... data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is a service ...
Breaking Biology Technology:
Cached News: