New research on investigational Alzheimer's disease treatment suggests significant improvement of symptoms

Reminyl's Dual Mode of Action Provides Novel Approach for Treatment

7 April 2000, Stockholm -- Results from a new five-month study conducted by Janssen Research Foundation show that patients who were treated with Reminyl® (galantamine), a new treatment for Alzheimer's disease showed a significant improvement in their cognitive, functional and behavioural symptoms, when measured by commonly-used assessments of the severity of Alzheimer's disease. The study is being presented today for the first time at the International Stockholm/Springfield Symposium, a meeting of leading experts to discuss advances in Alzheimer's therapy.

After 5 months, patients who were treated with 16 mg/day and 24 mg/day of Reminyl had significantly better scores on all efficacy measures compared to placebo (p<0.001 for both doses). "For the first time, we are able to show that Reminyl has benefits not only on cognition, but on patients' ability to function, while also postponing the emergence of behavioural symptoms," commented Pierre Tariot, MD, a Reminyl investigator and professor of psychiatry, medicine and neurology at the University of Rochester Medical Center, New York. "Even the most basic improvement of symptoms, such as being able to prepare a meal on their own or remembering the events of the day, can provide relief for patients and often their caregivers."

Efficacy was measured using a variety of subscales including the Alzheimer's Disease Assessment Scale (ADAS-cog), which measures a patient's memory, language, orientation and other aspects of cognition; the Clinician's Interview-Based Impression of Change plus Caregiver Input (CIBIC-plus), which provides a global assessment of behaviour, general psychiatric symptoms, cognition and activities of daily living; the 23-item version of the Alzheimer's Disease Cooperative Study Inventory (ADCS-ADL), which also measures activities of daily living; and the NeuroPsychiatric Invent

Contact: Roseann Ward/Louise Strong

Page: 1 2

Related biology news :

1. Leader in cancer treatment and prevention research honored
2. UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
3. Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
4. Belgian researchers explore revolutionary approach to angiogenesis
5. Award winning researchers reveal potential new role for Glivec
6. New research shows plants can shuffle and paste gene pieces to generate genetic diversity
7. 16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
8. Gene chips research in cotton could lead to superior variety
9. Groundbreaking research could ignite new solutions to heat transfer in nano-devices
10. New hydrothermal vents discovered as South Pacific Odyssey research begins
11. University of Alberta researcher looks for clues to mysterious disease

Post Your Comments:

(Date:8/14/2019)... TORONTO (PRWEB) , ... August 14, 2019 , ... Join ... live session on Tuesday, September 10, 2019 at 1pm EDT to learn ... stratification and effective management. , NAFLD is the most common diffuse liver disease, ...
(Date:8/14/2019)... ... August 14, 2019 , ... Gateway Genomics , ... children, announces inclusion in the 38th annual Inc. 500|5000 list of fastest ... To qualify, companies must have been founded and generating revenue by March 31, 2015. ...
(Date:8/14/2019)... ... ... Julie Reck of Veterinary Medical Center of Fort Mill has recently begun providing ... her own geriatric Australian Shepherd, Simon, was treated in June 2019 for osteoarthritis in his ... body was weak, and he struggled to play fetch and other games with his family. ...
Breaking Biology News(10 mins):
(Date:9/11/2019)... ... September 09, 2019 , ... Suvoda LLC ... and drug supply chain management, today announced its new technology partnership with ... , “The integration between Veeva Vault EDC and our IRT will enable sponsors ...
(Date:9/8/2019)... YORK (PRWEB) , ... September 04, 2019 , ... ... New York Academy of Sciences announced today the three Winners and six ... outstanding postdoctoral scientists from academic research institutions across New York, New Jersey, and ...
(Date:8/29/2019)... ... August 29, 2019 , ... Scientists have mapped the ... hope will ultimately help protect the multibillion-dollar grape industry that produces juice, jelly, ... faculty and alumni sequenced the microbiome found within tumors of grapevines afflicted with ...
(Date:8/27/2019)... ... 27, 2019 , ... Modality Solutions , an Inc. ... Consulting Engineer, Robert Battista, to Senior Consulting engineer. , In his new leadership ... new engineers as well as the creation of additional business opportunities and cutting-edge ...
Breaking Biology Technology:
Cached News: