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New small gene class found by Dartmouth geneticists may exert far reaching influence on cell behavior

collaborations to explore intriguing possibilities and the outcomes can be useful and far ranging. An area rich for collaborative investigation is in the field of genomics, which encompasses volumes of information and poses computational challenges.

"Weve developed and applied a way of finding many of a new class of genes and think that in a year we may have found all of the C. elegans miRNAs. If we do, were not focussing on one gene like we used to, but a whole class of genes," Ambros said. "Wed like to answer broad questions about how they work as well as specific questions about individual genes. The challenges escalate as the number of genes increase and the analyses become more complex. With lots of data we have to be able to weed out whats garbage and whats real so computer tools and bioinformatics expertise are essential."


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Contact: Hali Wickner
hali.wickner@dartmouth.edu
603-650-1520
Dartmouth Medical School
25-Oct-2001


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