HOME >> BIOLOGY >> NEWS
New study clarifies connection of brain and heart failure

y inducing the release of mediators that do penetrate the barrier. These neuroactive substances are released in excess by peripheral tissues under the stress of heart failure and signal the brain to alter volume regulation and autonomic function. Interestingly, the cardiovascular regions of forebrain that sense and respond to circulating peptides also process the signals originating in cardiovascular afferent nerves and are capable of modulating cardiovascular reflexes.

Until now, the potential importance of humoral heart-brain signaling in the pathogenesis of heart has not been fully examined. A new study summarizes recent studies supporting the concept that the forebrain plays a critical role in the pathogenesis of ischemia-induced heart failure and suggesting that the forebrain contribution must be considered in designing therapeutic strategies. Of particular emphasis in this study is the concept of forebrain signaling by neuroactive products of the renin-angiotensin system and the immune system.

A New Study

The authors of "Heart Failure and the Brain: New Perspectives," are Joseph Francis, Zhi-Hua Zhang, Shun-Guang Wei, and Alan Kim Johnson, from the University of Iowa and Robert B. Felder and Robert M. Weiss, representing the Research Service, Department of Veterans Affairs Medical Center, all in Iowa City, IA. Their findings appear in the February 2003 edition of the American Journal of Physiology Regulatory, Integrative and Comparative Physiology.

Methodology

A rat model with ischemia-induced heart failure allowed both acute and chronic interventions to address the key questions regarding the contribution of the forebrain to the progression to heart failure after a myocardial infarction (MI), more commonly known as a heart attack. The key question to be addressed was "How important is forebrain activation to the course of heart failure after MI?"

To further define the mechanisms activating t
'"/>

Contact: Donna Krupa
djkrupa1@aol.com
703-527-7357
American Physiological Society
18-Mar-2003


Page: 1 2 3 4

Related biology news :

1. Student science contest participation influences study, career choices, alumni say
2. New study shows hope for treating inhalant abuse
3. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
4. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
5. New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
6. Phase II trials of second-generation antisense cancer drug planned following successful early study
7. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
8. Indiana University, EPA to study airborne PCBs
9. K-State, other universities to study how climate affects plant evolution
10. USC study links historical increases in life span to lower childhood exposure to infection
11. Washington University in St. Louis leads group studying aging process

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/9/2017)... VIEW, Calif. , March 9, 2017 ... 23andMe , the leading personal genetics company, are using ... now provide customers with personalized nutrition plans that consider ... but also genetic markers impacting how their body may ... food decision support platform uses biometrics such as Body ...
(Date:3/7/2017)... , March 7, 2017   HireVue , the ... global companies identify the best talent, faster, today announced ... Sales Officer (CSO) and Diana Kucer as ... out a seasoned executive team poised to drive continued growth ... on a year of record bookings in 2017. ...
(Date:3/2/2017)... -- Summary This report provides all the information ... and activities since 2010. ... Read the full report: http://www.reportlinker.com/p03605615-summary/view-report.html ... provides an in-depth insight into the partnering activity of one ... demand company reports are prepared upon purchase to ensure inclusion ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... ... April 26, 2017 , ... Looking ... team-building and cooking events company, offers one-of-a-kind gifts, ranging from gourmet cooking experiences ... California cuisine, and guests leave inspired with new cooking tips and techniques, thanks ...
(Date:4/26/2017)... Palo Alto, CA, USA (PRWEB) , ... April ... ... ComplianceOnline’s popular seminar on FDA’s GMP expectations for phase I clinical trials comes ... was attended by various biotechnology and pharma professionals representing FDA regulated organizations such ...
(Date:4/26/2017)... ... 26, 2017 , ... Baltimore bio tech firm, PathSensors, Inc., ... solution at the National Postal Forum 2017 in Baltimore, Maryland, May 21st through ... easy to use and low cost threat detection solution for government and commercial ...
(Date:4/26/2017)... RESTON, Va. (PRWEB) , ... April 26, 2017 ... ... to make headlines and drive high-level conversations among healthcare industry stakeholders, the discussion ... Healthcare Environment – taking place May 15-18, 2017 in Los Angeles, Calif. Hosted ...
Breaking Biology Technology:
Cached News: