HOME >> BIOLOGY >> NEWS
New study indicates arsenic could be suitable as first-line treatment in type of leukaemia

Geneva, Switzerland: Arsenic trioxide a highly poisonous substance best known as an effective weed killer or pesticide and notorious for being a favourite 'weapon' of choice in murder mystery novels, is being re-invented as a treatment for a rare type of leukaemia.

It is already licensed as an orphan drug (the term for drugs intended to treat rare conditions) for patients who have relapsed after initial therapy for acute promyeloctytic leukaemia (APL).

But now, a research team led by Dr. Ardeshir Ghavamzadeh and Dr. Kamran Alimoghaddam at Tehran University of Medical Sciences in Iran, are running a trial of its use in newly diagnosed APL patients who have received no prior therapy, and they are impressed enough with its effectiveness to suggest that it should now be considered as a first-line treatment for APL. They also believe it is likely to prove effective in other cancers such as multiple myeloma.

Dr. Ghavamzadeh, professor of medicine at Tehran University, today (Wednesday 29 September) reported at the EORTC-NCI-AACR[1] Symposium on Molecular Targets and Cancer Therapeutics in Geneva that two courses of the drug achieved complete remission in over 90% of the 63 patients in a Phase II study being carried out at the city's Hematology, Oncology and Bone Marrow Transplant Center. 88.5% of patients were still alive with a mean survival time to date of nearly 34 months. Of 11 patients who relapsed, eight went back into remission after a third cycle of treatment. Six patients in the trial have died.

APL accounts for around 10% of acute myeloid leukaemias and affects an estimated 20,000 people worldwide each year. It is a cancer of the white blood cells, characterized by a rapid accumulation of abnormal white cells in the bone marrow and the blood, resulting in anaemia, bleeding and susceptibility to infections. It occurs in people of all ages, although it is more common in older people. The five-year survival rate for patients receiv
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
41-227-612-205
European Organisation for Research and Treatment of Cancer
29-Sep-2004


Page: 1 2 3

Related biology news :

1. Student science contest participation influences study, career choices, alumni say
2. New study shows hope for treating inhalant abuse
3. International study findings link acne-like rash to effectiveness of new targeted cancer treatment
4. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
5. Phase II trials of second-generation antisense cancer drug planned following successful early study
6. Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
7. Indiana University, EPA to study airborne PCBs
8. K-State, other universities to study how climate affects plant evolution
9. USC study links historical increases in life span to lower childhood exposure to infection
10. Washington University in St. Louis leads group studying aging process
11. Simian virus 40 not associated with non-Hodgkin lymphoma, study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. Mohamed Anwar ... the prestigious international IAIR Award for the most innovative high security ePassport ... ... Maldives Immigration Controller General, Mr. ... on the right) have received the IAIR award for the "Most innovative ...
(Date:3/23/2017)... , March 23, 2017 The report "Gesture Recognition ... Biometric), Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, the ... a CAGR of 29.63% between 2017 and 2022. ... ... ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... , ... April 20, 2017 , ... NetDimensions appoints Bill ... , With over 20 years of experience in the learning technologies industry, Mastin joins ... company within Learning Technologies Group plc (LTG). At LEO, Mastin served as SVP of ...
(Date:4/20/2017)... ... April 20, 2017 , ... Open Therapeutics ... property (IP) sharing and commercialization model. , The Center for Advancing Innovation helps ... of this effort is bringing the IP to the attention of the entrepreneurial ...
(Date:4/19/2017)... (PRWEB) , ... April 18, 2017 , ... ... 1970s and has been a key device for generating monodisperse droplets of known ... droplet processes and for generating monodisperse solid particles by drying monodisperse droplets. ...
(Date:4/19/2017)... ... April 19, 2017 , ... Nobilis Therapeutics Announces ... Seeks to Leverage Clinical Data in its Upcoming Post Traumatic Stress Disorder Trial , ... 81 patient clinical trial assessing efficacy of its NBTX-001, a xenon-based therapeutic in the ...
Breaking Biology Technology:
Cached News: