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New study tightens the link between smoking and early menopause

ual molecular mechanism that triggers inappropriate death of eggs after exposure to PAHs. We need to get people away from thinking that toxic chemicals cause general harm. Here we have mapped how a chemical, through several discrete steps, influences specific genetic events that lead to cell death, he says.

Tilly hopes this new human-graft mouse model will also allow researchers to conduct studies of other potential biohazards and drugs for their effects on the health of womens eggs. For the first time, we have the right population of human eggs, in a natural, nourishing, living environment not in a petri dish in the lab, says Tilly.


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Contact: Georgia W. Peirce
gpeirce@partners.org
617-724-6423
Massachusetts General Hospital
15-Jul-2001


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