The technology, known as Microbial Anti-attachment Technology (MAT) was developed by Dr. Shamim Ansari and colleagues at the Colgate-Palmolive Technology Center in Piscataway New Jersey.

The clinical data demonstrate that fewer bacteria bind to hand skin after washing with this soap technology. Since bacteria survive for several hours on objects such as doorknobs, telephones, toys, etc., a technology that reduces the acquisition of bacteria by the skin would not only offer a consumer-relevant benefit but also would provide a new paradigm in germ control, says Dr. Shamim. Currently, this technology is available in Colgates Protex Bar Soap throughout Latin America.

MAT is based on three commonly used cosmetic ingredients--petrolatum, dimethicone, and polyquaternium--that prevent bacteria from adhering to the skin. The researchers hypothesize that MAT ingredients deposit a thin film on the surface of the skin, blocking specific bacteria-binding sites and/or altering the surface properties of the skin.

The researchers tested MAT using Serratia marcescens, a bacterium that forms a distinctive red colony and is not normally found on the skin. In these studies, one hand was washed with a placebo or commercially available soap while the other with a soap-containing MAT. After drying, hands were contaminated by lightly pressing them against a plastic surface pre-coated with the marker bacteria. The bacteria transferred from the plate to the hands were recovered and quantified by standard microbiological methods. In three clinical studies, the bacteria attachment to the hands washed with the MAT-containing soap was reduced by a statistically significant 50-58% relative to the hands washed with placebo o
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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
20-May-2002