HOME >> BIOLOGY >> NEWS
New technology will speed genome sequencing

CAMBRIDGE, Mass. Almost 150 different genomes have been sequenced to date, including the human genome. But sequencing needs are growing faster than ever: In March 2003, the Bush administration announced it will spend $1 billion over five years to increase forensic analysis of DNA, including a backlog of up to 300,000 samples. And the success of the growing field of genomic medicine, which promises to deliver better therapies and diagnostics, depends on faster sequencing technology.

This fall, researchers at Whitehead Institute will test new technology that could aid these and other endeavors. The BioMEMS 768 Sequencer can sequence the entire human genome in only one year, processing up to 7 million DNA letters a day, about seven times faster than its nearest rival. Scientists began working on the project in 1999 with a $7 million National Human Genome Research Institute grant. The technology eventually will help scientists quickly determine the exact genetic sequence of the DNA of many different organisms, and could lead to faster forensic analysis of DNA gathered in criminal cases.

The heart of the new BioMEMs machine is a large glass chip etched with tiny microchannels called "lanes." It tests 384 lanes of DNA at a time, four times more than existing capillary sequencers. Each lane can accommodate longer strands of DNA: about 850 bases (the nucleic acids found in DNA, abbreviated by the letters A, C, T or G), compared to the current 550 bases per lane.

It takes about 45 minutes to read the DNA from one of the BioMEMS' 768 lanes. The machine has two chips; one is prepared as the other is sequenced, so that the machine is sequencing at all times. The new sequencer saves not just capital costs, the developers say, but day-to-day expenses as well.

"It's not only the cost of the machine, but the cost of the materials it uses," says Brian McKenna, a senior software engineer at Whitehead Institute. The goal, he says, is to use the same a
'"/>

Contact: Kelli Whitlock or David Cameron
newsroom@wi.mit.edu
617-258-5183
Whitehead Institute for Biomedical Research
20-Nov-2003


Page: 1 2

Related biology news :

1. Yale digital diagnostic technology is basis of new company, HistoRx Inc.
2. AACR applauds NCI initiative on nanotechnology
3. Rensselaer marks the opening of the center for biotechnology and interdisciplinary studies
4. New imaging technology at Joslin shown to detect early signs of type 1 diabetes
5. Researchers show how to assemble building blocks for nanotechnology
6. Jefferson Lab detector technology aids development of cystic fibrosis therapy
7. National Academies Advisory: Sept. 18-19 Nanotechnology Conference
8. New diagnostic technology helps justify earlier cataract surgery
9. New textbook introduces students to the foundations, applications of nanotechnology
10. UK biotechnology business plan competition now open to students in the US and Canada
11. The future of nanotechnology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/22/2017)... NEW YORK , March 21, 2017 /PRNewswire/ ... Customer Marketing Cloud used by retailers such as ... in its platform — Product Recommendations and Replenishment. Using ... to give more personalized product and replenishment recommendations ... purchases, but also on predictions of customer intent ...
(Date:3/20/2017)... At this year,s CeBIT Chancellor Dr. Angela Merkel visited the ... the DERMALOG stand together with the Japanese Prime Minster Shinzo Abe. ... largest German biometrics company the two government leaders could see the three ... as DERMALOG´s multi-biometrics system.   Continue Reading ... ...
(Date:3/16/2017)... - Against identity fraud with DERMALOG solutions "Made in Germany "  ... ... multi-biometric solutions provide a crucial contribution against identity fraud. (PRNewsFoto/Dermalog Identification Systems) ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity ... ...
Breaking Biology News(10 mins):
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... Ken Hanson, ... president of Physik Instrumente USA, have been selected as this year’s recipients of two ... The two have been invited along with other honorees to accept their awards at ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... flying hobbyists, and the University Aviation Association (UAA), the unifying voice for collegiate ... Collegiate Challenge will encourage teamwork, competition, and success through a STEM-based education platform. ...
(Date:6/22/2017)... ... June 21, 2017 , ... RMC Pharmaceutical Solutions, Inc. announces ... Reinhardt to manage the new site. , Tim has 25 years of pharmaceutical ... recent role as the Director of Manufacturing and Supplier Quality Assessment. This ...
(Date:6/22/2017)... ... June 22, 2017 , ... AESKU.GROUP, ... DST Diagnostische Systeme & Technologien GmbH, thereby expanding its product portfolio to include ... hay fever, urticaria, asthma, atopic eczema or a food allergy. Allergies are escalating ...
Breaking Biology Technology:
Cached News: