HOME >> BIOLOGY >> NEWS
New test offers hope of easy and affordable screening for hereditary breast cancer genes

Researchers at the Nottingham Breast Unit in the UK have developed an easy and affordable way of screening families for underlying hereditary genetic mutations which predispose them to developing breast cancer, the 3rd European Breast Cancer Conference in Barcelona heard today (Wednesday 20 March).

By testing samples from either two family members affected by breast cancer or from one family member with two tumours, the new test can indicate the presence of mutations in breast cancer genes in 50% of cases, and possibly even more. Once the test has given this indication, doctors can then go on to carry out genetic mutation analysis in only those families where the test has shown a mutation is most likely to be present, and so cut costs by avoiding unnecessary analyses.

Jos Cid, who carried out the research while he was a clinical research fellow at the Breast Unit, told the conference that an added advantage of this test is that it can be carried out on tumour material stored from previous operations, which enables families to be tested for the presence of a gene mutation when the relative with cancer has already died.

He said: At present, women who have a high chance of carrying a gene mutation are seen in the family history clinic, where they are offered gene testing only after a full mutational analysis has been done first in the blood of an alive, affected relative. This is time-consuming and expensive. Our alternative procedure requires analysis also in relatives, but this can be done in tissue stored from an operation sometimes carried out many years ago, and it is quick, easy and affordable.

Mr. Cid recruited 67 families who were expected to be at high risk of developing hereditary breast cancer from the strength of their family history. He did not know in advance whether or not they had mutations in the breast cancer genes BRCA1 and BRCA2.

He analysed samples from two tumours per family (the majority of families
'"/>

Contact: Emma Mason
wordmason@aol.com
+44-0-7711-296-986
Federation of European Cancer Societies
20-Mar-2002


Page: 1 2 3

Related biology news :

1. Lake research offers clues to managing crayfish invasions
2. Comparing primate genomes offers insight into human evolution
3. Study of proteins offers insights into organization of biological networks
4. Susceptibility of mice to mousepox offers promise of smallpox protection
5. Botulinum toxin structure offers clues for vaccines/treatments
6. Discovery offers clues to origin of life
7. Guiding gas exploration: U-M research offers inexpensive tool
8. New approach offers potential drug-discovery shortcut
9. American Society of Plant Biologists offers developing nations free access to science journals
10. Study offers new model for breast cancer
11. Rutgers researcher offers a new perspective on human evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2019)... ... August 15, 2019 , ... Deep Science Ventures (DSV), ... Agriculture practice, a new unit dedicated to building 100 companies over the next 10 ... and supply chains. , Deep Science Ventures was founded to create a better ...
(Date:8/14/2019)... ... August 14, 2019 , ... Join Jonathan Riek, PhD, VP, Musculoskeletal & ... September 10, 2019 at 1pm EDT to learn about two common imaging methods in ... NAFLD is the most common diffuse liver disease, with a worldwide prevalence of 20-46 ...
(Date:8/9/2019)... ... , ... With a demand in healthcare to lower unneeded emergency room visits ... centers (UCC) in the coming years, according to a new report on the industry ... Centers , is a detailed look at the current state of these healthcare outlets, ...
Breaking Biology News(10 mins):
(Date:7/9/2019)... , ... July 08, 2019 , ... ... The company’s SmartLight Indicator was recognized as the 2019 Innovative Product of the ... forward. The prestigious awards were during Sensors Expo & Conference 2019, ...
(Date:6/26/2019)... , ... June 26, 2019 , ... Alice Branton today ... on improving physicochemical properties of Magnesium Gluconate, which can prove to be beneficial for ... alteration of characteristic differentiation peak, change in crystallite size , Over 142% ...
(Date:6/18/2019)... Calif. (PRWEB) , ... June 18, 2019 , ... ... an Investigational New Drug (IND) application to the FDA for use of a person’s ... cells as a treatment of osteoarthritis in the knee. This IND is the ...
(Date:6/11/2019)... ... 10, 2019 , ... Thought Technology Ltd is pleased to ... Biofeedback Tech Ltd as its authorised distributor for the UK and Ireland. ... treatments and clinical assessment protocols to treat stress related disorders as well as ...
Breaking Biology Technology:
Cached News: