HOME >> BIOLOGY >> NEWS
New test offers hope of easy and affordable screening for hereditary breast cancer genes

Researchers at the Nottingham Breast Unit in the UK have developed an easy and affordable way of screening families for underlying hereditary genetic mutations which predispose them to developing breast cancer, the 3rd European Breast Cancer Conference in Barcelona heard today (Wednesday 20 March).

By testing samples from either two family members affected by breast cancer or from one family member with two tumours, the new test can indicate the presence of mutations in breast cancer genes in 50% of cases, and possibly even more. Once the test has given this indication, doctors can then go on to carry out genetic mutation analysis in only those families where the test has shown a mutation is most likely to be present, and so cut costs by avoiding unnecessary analyses.

Jos Cid, who carried out the research while he was a clinical research fellow at the Breast Unit, told the conference that an added advantage of this test is that it can be carried out on tumour material stored from previous operations, which enables families to be tested for the presence of a gene mutation when the relative with cancer has already died.

He said: At present, women who have a high chance of carrying a gene mutation are seen in the family history clinic, where they are offered gene testing only after a full mutational analysis has been done first in the blood of an alive, affected relative. This is time-consuming and expensive. Our alternative procedure requires analysis also in relatives, but this can be done in tissue stored from an operation sometimes carried out many years ago, and it is quick, easy and affordable.

Mr. Cid recruited 67 families who were expected to be at high risk of developing hereditary breast cancer from the strength of their family history. He did not know in advance whether or not they had mutations in the breast cancer genes BRCA1 and BRCA2.

He analysed samples from two tumours per family (the majority of families
'"/>

Contact: Emma Mason
wordmason@aol.com
+44-0-7711-296-986
Federation of European Cancer Societies
20-Mar-2002


Page: 1 2 3

Related biology news :

1. Lake research offers clues to managing crayfish invasions
2. Comparing primate genomes offers insight into human evolution
3. Study of proteins offers insights into organization of biological networks
4. Susceptibility of mice to mousepox offers promise of smallpox protection
5. Botulinum toxin structure offers clues for vaccines/treatments
6. Discovery offers clues to origin of life
7. Guiding gas exploration: U-M research offers inexpensive tool
8. New approach offers potential drug-discovery shortcut
9. American Society of Plant Biologists offers developing nations free access to science journals
10. Study offers new model for breast cancer
11. Rutgers researcher offers a new perspective on human evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2018)... ... ... Lecomte is hard at work on his second ocean crossing. After becoming the first human ... Tokyo to San Francisco, churning his limbs eight hours a day in the cold Pacific ... of its kind, The Swim is far more than just an extreme sport. Besides the ...
(Date:8/31/2018)... ... 30, 2018 , ... USDM Life Sciences , the leading risk management, ... has received the 2018 Services Partner of the Year, Awarded for Innovation from Box, ... Business Development and Platform Sales, Niall Wall and received by USDM Life Sciences CEO, ...
(Date:8/26/2018)... ... August 23, 2018 , ... Clinical laboratories have increasingly ... over more commonly used analytical techniques. However, implementation can be daunting due to ... validation of methods that must be undertaken by the laboratory if they are ...
Breaking Biology News(10 mins):
(Date:8/29/2018)... (PRWEB) , ... August 28, 2018 , ... ... nano-technology enhanced spinal implants, announced today the successful completion of a $5.5 million ... Capital Corporation, Purdue’s Foundry Investment Fund, Commenda Capital, and Ellipsis Ventures. , “Our ...
(Date:8/29/2018)... Calif. (PRWEB) , ... August 28, 2018 , ... ... scientists from around the world, is proud to announce the launch of a new ... offers for a chance to win one of LabRoots most popular shirts. , Throughout ...
(Date:8/23/2018)... , ... August 22, 2018 , ... ... for Android on September 1st, making it the first fully-featured app for electronic ... Android devices. Combined, iOS and Android constitute 99 percent of the market share ...
(Date:8/17/2018)... ... August 16, 2018 , ... The opening of the new ... Chemko Technical Services in 2016. Chemko had a well established local presence, servicing the ... KSC on projects such as the ongoing work at the Mobile Launch Platform (MLP) ...
Breaking Biology Technology:
Cached News: