HOME >> BIOLOGY >> NEWS
New transgenic rat model of ALS expands research possibilities

human patients and SOD1 transgenic mice and rats, globs of faulty SOD1 proteins are found. Scientists know that loss of SOD1 function isn't to blame for the symptoms of ALS; instead, the faulty enzyme picks up a new, still unknown, function.

Finding the link between faulty SOD1 and the disappearing glutamate transporter should help clarify why the many SOD1 mutations appear in patients with inherited ALS and even in some non-inherited cases of the disease, says Rothstein.

The investigations were stimulated by The ALS Association, and funded by the National Institutes of Health, the Center for ALS Research at Johns Hopkins, the Spinal Cord Disease Foundation and the Ludwig Institute for Cancer Research. The Center for ALS Research at Johns Hopkins, formed in March 2000, is a collaboration of scientists worldwide rapidly working to develop new treatments and to find a cure for ALS.


'"/>

Contact: Joanna Downer
jdowner1@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
28-Jan-2002


Page: 1 2 3

Related biology news :

1. Inhibition of cathepsin proteases inhibits tumor formation in transgenic mice
2. UGA researchers use transgenic trees to help clean up toxic waste site
3. Could Bt transgenic crops have nutritionally favourable effects on insects?
4. Scientists transgenic chicken aids embryo research
5. Scientists report first transgenic animal developed via retroviral DNA insertion into male germ-line stem cells
6. Eating transgenic sausages
7. Dairy scientist advances field of transgenics and knowledge of growth hormones
8. Scientists develop most efficient mouse cloning strategy to date, create transgenic clone
9. New transgenic mouse likely to advance Alzheimers disease research
10. University of Florida researchers test drug from transgenic sheep in study at Shands at UF teaching hospital
11. Jefferson scientists create first transgenic mouse model of hepatitis B-based liver disease

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New transgenic rat model ALS expands research possibilities

(Date:5/25/2015)...  Australia,s market for wearable technologies is considered to ... advent of several trials and prototypes. The release of ... to ignite interest in wearables as well as accelerate ... . This in turn will spur greater innovation from ... amongst vendors and distributors. Photo - ...
(Date:5/21/2015)... 21, 2015 According to ... Solutions (Hardware, Software, Services), by Applications (Surveillance (Airborne, ... by End-Users (Military & Defense & Commercial) - ... Imaging Market is expected to grow from $7252.0 ... at a Compound Annual Growth Rate (CAGR) of ...
(Date:5/20/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... LLC, a company engaged in biometric identification is an ... portion of the recently awarded TIES (Technical Information Engineering ... Army. 3D-ID LLC has a suite of ... and security agencies. Gino Pereira , ...
Breaking Biology News(10 mins):Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3
(Date:5/29/2015)... IRVING, Texas , May 29, 2015 /PRNewswire/ ... company focused on fulfilling the promise of precision ... five studies that demonstrate the clinical utility of ... comprehensive tumor profiling service, in helping to identify ... aggressive tumors. In each of the studies, results ...
(Date:5/29/2015)... Translation is frequently listed as one of ... reason--if used in a way that is right for a ... business product or service offering. , Here are some ... effect on a company's bottom line: , 1.    Attract bigger audience. ... world can use, why not offer it globally? Nelson Mandela ...
(Date:5/28/2015)... , May 27, 2015 ... the addition of Jain PharmaBiotech,s new report ... to their offering. An increasing ... biotechnology industries is anticipated. Nanotechnology will be ... - from formulations for optimal delivery to ...
(Date:5/28/2015)... Celsion Corporation (the "Company") (NASDAQ: CLSN ... two institutional healthcare investors to purchase an aggregate of ... an at-the-market registered direct offering and a concurrent private ... The Company entered into a definitive purchase agreement with ... sell an aggregate of 3,000,000 shares of its common ...
Breaking Biology Technology:Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 2Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 3Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 4Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 5Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 6Three Ways Translation Can Help Businesses Grow 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 2Global Nanobiotechnology Market 2015-2024 - Applications, Markets and Companies 3Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 3
Cached News: