HOME >> BIOLOGY >> NEWS
New view of evolving genes, proteins to aid bioinformatics

Rockville, MD -- Today's evolutionary theory is not enough to tell us how even simple mutation biases may skew the evolutionary process, according to a report by scientists from the University of Maryland Biotechnology Institute (UMBI).

In the March edition of the journal Evolution and Development, research associate Lev Yampolsky and research biologist Arlin Stoltzfus of UMBI's Center for Advanced Research in Biotechnology (CARB) make a case that simple biases in mutation will change the evolutionary process. They use mathematics and computer simulations to explore the role of mutation biases using the classic "Bateson-Dobzhansky-Muller" model.

"Recognizing this kind of bias as an evolutionary cause will increase our ability to explain and predict evolution, and will aid researchers as they seek to understand such things as the amino acid composition of proteins, the appearance of new strains of viruses strains, and the distribution of introns in genes, all of which exhibit components of change that suggest a role of biases in the process of mutation," explains Stoltzfus. (Introns are DNA sequences in genes that don't encode proteins, thus having no defined purpose.)

The CARB study also helps to make more sense of the results of the rapidly growing science of bioinformatics, the data analysis of genomes and proteins. Since the 1970's when the technique of gene sequencing was developed, evidence has been accumulating that mutation biases strongly influence the evolution of genes and proteins, say the authors. The influence has been interpreted as a sign of "neutral evolution", a kind of random noise in the evolutionary process.

But now Yampolsky and Stoltzfus argue that in a more general theory, mutation-biased evolution does not have to be neutral.

In historic perspective, the new paper shows that it is still possible to stake out a new position on an old issue in evolutionary theory. Charles Darwin and other 19th century scientists realiz
'"/>

Contact: Steve Berberich
berberic@umbi.umd.edu
301-738-6295
University of Maryland Biotechnology Institute
12-Mar-2001


Page: 1 2

Related biology news :

1. Technique plucks rapidly evolving genes from a pathogens genome
2. Rapidly evolving genes providing new insights in plant evolution
3. In mutually beneficial relationship, slowest-evolving species gains upper hand
4. University of Cincinnati geologist finds survival benefit to evolving after mass extinctions
5. Therapy hinders AIDS virus from evolving drug resistance, Hopkins researchers find
6. Rapid size change in introduced fruit fly indicates it is evolving as it invades North America
7. Tracing genes, biologists show lizard migration is traced to Florida
8. Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis
9. Heart may heal with help from oxygen-sensitive genes, new study suggests
10. Family history doesnt predict colon cancer genes, behavior
11. Modified zebrafish may point the way toward T cell leukemia genes, aid in drug development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
(Date:5/20/2016)... -- VoiceIt is excited to announce its new marketing ... working together, VoiceIt and VoicePass will offer an ... slightly different approaches to voice biometrics, collaboration between ... Both companies ... "This marketing and technology partnership allows VoiceIt ...
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...   Ginkgo Bioworks , a leading organism ... today awarded as one of the World Economic ... most innovative companies. Ginkgo Bioworks is engineering biology ... world in the nutrition, health and consumer goods ... customers including Fortune 500 companies to design microbes ...
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal articles ... findings are the subject of a new article on the Surviving Mesothelioma website. ... blood, lung fluid or tissue of mesothelioma patients that can help point doctors to ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, into ... for over 35 years, is proud to add Target to its list of ...
Breaking Biology Technology:
Cached News: