HOME >> BIOLOGY >> NEWS
New view of evolving genes, proteins to aid bioinformatics

Rockville, MD -- Today's evolutionary theory is not enough to tell us how even simple mutation biases may skew the evolutionary process, according to a report by scientists from the University of Maryland Biotechnology Institute (UMBI).

In the March edition of the journal Evolution and Development, research associate Lev Yampolsky and research biologist Arlin Stoltzfus of UMBI's Center for Advanced Research in Biotechnology (CARB) make a case that simple biases in mutation will change the evolutionary process. They use mathematics and computer simulations to explore the role of mutation biases using the classic "Bateson-Dobzhansky-Muller" model.

"Recognizing this kind of bias as an evolutionary cause will increase our ability to explain and predict evolution, and will aid researchers as they seek to understand such things as the amino acid composition of proteins, the appearance of new strains of viruses strains, and the distribution of introns in genes, all of which exhibit components of change that suggest a role of biases in the process of mutation," explains Stoltzfus. (Introns are DNA sequences in genes that don't encode proteins, thus having no defined purpose.)

The CARB study also helps to make more sense of the results of the rapidly growing science of bioinformatics, the data analysis of genomes and proteins. Since the 1970's when the technique of gene sequencing was developed, evidence has been accumulating that mutation biases strongly influence the evolution of genes and proteins, say the authors. The influence has been interpreted as a sign of "neutral evolution", a kind of random noise in the evolutionary process.

But now Yampolsky and Stoltzfus argue that in a more general theory, mutation-biased evolution does not have to be neutral.

In historic perspective, the new paper shows that it is still possible to stake out a new position on an old issue in evolutionary theory. Charles Darwin and other 19th century scientists realiz
'"/>

Contact: Steve Berberich
berberic@umbi.umd.edu
301-738-6295
University of Maryland Biotechnology Institute
12-Mar-2001


Page: 1 2

Related biology news :

1. Technique plucks rapidly evolving genes from a pathogens genome
2. Rapidly evolving genes providing new insights in plant evolution
3. In mutually beneficial relationship, slowest-evolving species gains upper hand
4. University of Cincinnati geologist finds survival benefit to evolving after mass extinctions
5. Therapy hinders AIDS virus from evolving drug resistance, Hopkins researchers find
6. Rapid size change in introduced fruit fly indicates it is evolving as it invades North America
7. Tracing genes, biologists show lizard migration is traced to Florida
8. Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis
9. Heart may heal with help from oxygen-sensitive genes, new study suggests
10. Family history doesnt predict colon cancer genes, behavior
11. Modified zebrafish may point the way toward T cell leukemia genes, aid in drug development

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New view evolving genes proteins aid bioinformatics

(Date:8/27/2014)... abandoned each year in U.S. waters and become what ... fish, crabs, and other species such as turtles. These ... watermen who depend on the resources--losses that are largely ... The report, published in the Marine Pollution Bulletin ... the derelict fish trap problem, and so-called "ghost fishing," ...
(Date:8/27/2014)... A growing number of studies have shown ... the pathogenesis of Parkinson,s disease. Previous studies ... Medical University in China have shown that ... injury, reduced divalent metal transporter 1 expression, ... substantia nigra of rotenone-induced Parkinson,s disease rats. ...
(Date:8/27/2014)... University of Adelaide research has shown that piglets can ... birthing frequency. , The outcome of the study at ... Animal Reproduction Science , is an important finding for ... welfare without loss of production. , "Sows don,t usually ... on heat after their piglets have been weaned," says ...
Breaking Biology News(10 mins):NOAA's Marine Debris Program reports on the national issue of derelict fishing traps 2Piglet weaning age no bar to litter frequency 2
(Date:8/27/2014)... TX (PRWEB) August 27, 2014 The ... and in-depth study on the current state of the ... report provides a basic overview of the industry, including ... and Chinese domestic market analysis are provided with a ... the market. A comparison between the international and Chinese ...
(Date:8/27/2014)... , Aug. 27, 2014  A novel biomarker ... help physicians better identify early-stage disease, when treatment ... according to a new study in The Journal ... (NYSE: DGX ) and other institutions ... protein outperformed conventional antibody-serum testing, including rheumatoid factor ...
(Date:8/27/2014)... Flagship Biosciences LLC, a leading provider of ... and medical device industries, has announced a laboratory and ... has consolidated its histology and tissue analysis operations from ... just north of Denver. The new addresses are: ... Suite 100, Westminster, CO 80021 , Tissue Image Analysis ...
(Date:8/27/2014)... Aug. 27, 2014 Tris Pharma, a specialty ... today announced that it has been selected as an ... Association,s 2014 Awards for Excellence competition in ... independent panel of judges from SCORE (Counselors to America,s ... will be honored at a gala event to be ...
Breaking Biology Technology:Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 3Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 4Flagship Biosciences Announces Relocation and Expansion 2Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2
Cached News: