HOME >> BIOLOGY >> NEWS
New view of evolving genes, proteins to aid bioinformatics

Rockville, MD -- Today's evolutionary theory is not enough to tell us how even simple mutation biases may skew the evolutionary process, according to a report by scientists from the University of Maryland Biotechnology Institute (UMBI).

In the March edition of the journal Evolution and Development, research associate Lev Yampolsky and research biologist Arlin Stoltzfus of UMBI's Center for Advanced Research in Biotechnology (CARB) make a case that simple biases in mutation will change the evolutionary process. They use mathematics and computer simulations to explore the role of mutation biases using the classic "Bateson-Dobzhansky-Muller" model.

"Recognizing this kind of bias as an evolutionary cause will increase our ability to explain and predict evolution, and will aid researchers as they seek to understand such things as the amino acid composition of proteins, the appearance of new strains of viruses strains, and the distribution of introns in genes, all of which exhibit components of change that suggest a role of biases in the process of mutation," explains Stoltzfus. (Introns are DNA sequences in genes that don't encode proteins, thus having no defined purpose.)

The CARB study also helps to make more sense of the results of the rapidly growing science of bioinformatics, the data analysis of genomes and proteins. Since the 1970's when the technique of gene sequencing was developed, evidence has been accumulating that mutation biases strongly influence the evolution of genes and proteins, say the authors. The influence has been interpreted as a sign of "neutral evolution", a kind of random noise in the evolutionary process.

But now Yampolsky and Stoltzfus argue that in a more general theory, mutation-biased evolution does not have to be neutral.

In historic perspective, the new paper shows that it is still possible to stake out a new position on an old issue in evolutionary theory. Charles Darwin and other 19th century scientists realiz
'"/>

Contact: Steve Berberich
berberic@umbi.umd.edu
301-738-6295
University of Maryland Biotechnology Institute
12-Mar-2001


Page: 1 2

Related biology news :

1. Technique plucks rapidly evolving genes from a pathogens genome
2. Rapidly evolving genes providing new insights in plant evolution
3. In mutually beneficial relationship, slowest-evolving species gains upper hand
4. University of Cincinnati geologist finds survival benefit to evolving after mass extinctions
5. Therapy hinders AIDS virus from evolving drug resistance, Hopkins researchers find
6. Rapid size change in introduced fruit fly indicates it is evolving as it invades North America
7. Tracing genes, biologists show lizard migration is traced to Florida
8. Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis
9. Heart may heal with help from oxygen-sensitive genes, new study suggests
10. Family history doesnt predict colon cancer genes, behavior
11. Modified zebrafish may point the way toward T cell leukemia genes, aid in drug development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/30/2016)... -- higi SH llc (higi) announced today the launch ... industry thought-leaders and celebrity influencers looking to encourage, ... steps to live healthier, more active lives. ... built the largest self-screening health station network in ... have conducted over 185 million biometric screenings.  The ...
(Date:11/29/2016)... , November 29, 2016 Nearly one billion matches ... Reading ... DERMALOG ... of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric supplier: The company's ...
(Date:11/22/2016)... 22, 2016 According to the new market research ... Face, Vein, Signature, Voice), Multi-Factor), Component (Hardware and Software), Function (Contact and ... the market is expected to grow from USD 10.74 Billion in 2015 ... between 2016 and 2022. Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... ... December 07, 2016 , ... ... an early access program for SmartBiome -- a novel metagenomic deep-sequencing research ... specific enrichment and detection of hundreds of different genes. The selective early ...
(Date:12/6/2016)... ... December 06, 2016 , ... ... Group, the world’s largest privately-held contract pharmaceutical development and manufacturing organisation, ... leading biopharma outsourcing company combining a leading CRO and the industry’s only ...
(Date:12/6/2016)... Colorado (PRWEB) , ... December 06, 2016 , ... ... dynamic aqueous plasma technology platforms, announced today that the company has engaged in ... Research and Development Agreement (MRDA) with the CSU Office of the Vice President ...
(Date:12/6/2016)... 2016 Zimmer Biomet Holdings, Inc. (NYSE ... pricing terms of its previously-announced cash tender offers ... price (excluding accrued and unpaid interest to, but ... fees and expenses related to the Offers) (the ... in the table below (collectively, the "Notes"). The ...
Breaking Biology Technology:
Cached News: