HOME >> BIOLOGY >> NEWS
Newborn screening for certain genetic disorders has benefits and some drawbacks

CHICAGO -- Expanded newborn screening for biochemical genetic disorders may lead to improved health outcomes for affected children and lower stress for their parents, however, false-positive screening results may place families at risk of increased stress, according to a study in the November 19 issue of The Journal of the American Medical Association (JAMA).

According to background information in the article, routine newborn screening is required practice for newborn care throughout the United States. Traditionally, testing for various disorders required a separate test, but now with a measuring device called the tandem mass spectrometry, biochemical genetic screening of up to 20 disorders can be performed from only one blood sample from the newborn. To date 24 states have started this expanded newborn screening using tandem mass spectrometry. Four states have not yet implemented mandated programs and four states offer non-mandated expanded screening.

In this study, Susan E. Waisbren, Ph.D., from Children's Hospital, Boston, and colleagues compared newborn identification by expanded screening with clinical identification of biochemical genetic disorders. The researchers also assessed the impact on families of a false-positive screening result compared with a normal result. False-positive results are defined by the researchers as initial out-of-range screening results that do not signify a metabolic disorder on further evaluation of the child.

The sample included families of 50 affected children identified through expanded newborn screening and 33 affected children identified clinically. In addition, families of 94 children found to have false-positive newborn screening results and 81 children having normal newborn screening results were also enrolled. A total of 254 mothers and 153 fathers were interviewed.

"Within the first six months of life, 28 percent of children identified by newborn screening compared with 55 percent
'"/>

Contact: Susan Craig
617-355-6420
JAMA and Archives Journals
18-Nov-2003


Page: 1 2

Related biology news :

1. Newborns have ear preferences, too
2. Newborn lambs central heating system could aid fat busting in humans
3. International Study Finds Mothers Lifetime Lead Exposures May Put Breast-Fed Newborns At Risk
4. March of Dimes statement on newborn screening report
5. Only 21 states offer newborn screening tests recommended by March of Dimes
6. New screening method turns up potential compound for treating anthrax
7. Genetic screening study at Stanford IDs most aggressive adult leukemia strains
8. Genetic screening recommended to detect new neurodegenerative disorder in men over age 50
9. HPV testing could be future strategy for primary screening for cervical cancer
10. SARS pre-screening protocol developed for AACR Annual Meeting in Washington, D.C.
11. UNC HIV-AIDS screening, prevention method could become national model for cutting illness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... 05, 2020 , ... Regenative Labs has received approval from the Centers for ... them the first Wharton’s jelly allografts to be assigned a Q code and be ... the first Wharton’s jelly allograft product to be recognized as a 361 HCT/P by ...
(Date:7/31/2020)... (PRWEB) , ... July 30, 2020 , ... ... Research (SBIR) Phase II contract awarded by the Joint Science & Technology Office—Chemical ... this project is to develop, optimize, and scale-up a highly efficient mammalian cell ...
(Date:7/22/2020)... BARBARA, Calif. (PRWEB) , ... July 21, 2020 ... ... firm driving digital transformation and innovation in technology and compliance, announces a new ... medical device companies must ensure every layer of their technology stack complies with ...
Breaking Biology News(10 mins):
(Date:7/22/2020)... (PRWEB) , ... July 22, 2020 , ... Join experts ... John Lorenc, Sr. Manager Regulatory Solutions, in a one hour live webinar ... the regulating body in China for drugs and medical devices. Specifically, for medical devices, ...
(Date:7/10/2020)... (PRWEB) , ... July 08, 2020 , ... ... services and products, announces a significant expansion of laboratory operations through its ... for agencies implementing testing programs. , Bode-CARES provides a turnkey ...
(Date:7/7/2020)... , ... July 06, 2020 , ... ... Awards. Entries from Roche, Eli Lilly, Bristol-Myers Squibb, the University of Chicago, Massachusetts ... Bio-IT World has hosted an elite awards program, highlighting outstanding examples of how ...
(Date:6/28/2020)... (PRWEB) , ... June 25, 2020 , ... ... are racing to develop a vaccine or drug treatment. In an effort to ... has publicly released the world’s largest imaging dataset portraying therapeutic compound effects ...
Breaking Biology Technology:
Cached News: