HOME >> BIOLOGY >> NEWS
Newly invented Endometrial Function Test (EFT®) solves the puzzle of unexplained infertility

A Yale researcher who invented a test to determine whether a woman's endometrium (uterine lining) is healthy and ready for embryo implantation has identified two new biochemical markers that improve assessment of the endometrium.

The endometrial function test (EFT®) was created by Harvey J. Kliman, M.D., a research scientist in the Department of Obstetrics, Gynecology and Reproductive Sciences at the Yale School of Medicine. An abnormal EFT is associated with pregnancy failure, while a normal EFT is associated with pregnancy success. Kliman's study, published in the July issue of the journal Fertility and Sterility, identifies two new biochemical markers, cyclin E and p27, that more accurately assess endometrial health compared to the routine examination that is done by pathology laboratories.

"These findings will help women who have difficulty conceiving become pregnant at a reduced cost," said Kliman who likens the endometrium to soil and the embryo to a treasured plant. "Soil has to be tested and prepared in order for the plant to grow in it. The endometrium also has to be healthy and capable of supplying the appropriate nutrients for the embryo. If the right conditions do not exist, implantation will not occur. This test, which uses these new biochemical markers, will improve assessment of the endometrium."

Kliman said the most difficult step in the process of conception is the attachment (implantation) of the embryo to the endometrium. Abnormalities in the process of implantation are believed to be the basis of many cases of unexplained infertility in women. A normal healthy endometrium will make many different substances (markers). By measuring several of these markers in endometrial biopsies, researchers can determine if the endometrium is receptive to implantation. Kliman said the two new markers he used in his study are more effective at assessing endometrial health than the other markers studied to date or methods in current us
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
15-Jul-2003


Page: 1 2 3

Related biology news :

1. Newly identified master gene key in babys first breath
2. Newly discovered protein may be key to muscular dystrophy
3. Newly designed nanoparticle quantum dots simultaneously target and image prostate tumors in mice
4. Newly grown kidneys can sustain life in rats
5. Newly discovered gene controls levels of bad cholesterol in mice
6. Newly identified gene linked to brain development
7. Newly cloned gene key to global adaptation of wheat
8. Newly identified genes may help predict outcome in childhood leukemia
9. Newly identified gene may halt fuzzy, moldy fruit
10. Newly found gene resistant to economically crippling wheat disease
11. Newly mapped enzyme could yield new treatments for female sexual dysfunction

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/12/2019)... ... November 12, 2019 , ... ... from nonprofit U.S. universities and research institutions for its Instrumentation Grant for ... up to $1.2 million per site for the acquisition of instrumentation, development and ...
(Date:11/7/2019)... (PRWEB) , ... November 07, 2019 , ... R3 Stem ... 50% off through the rest of 2019. The code to use during checkout is ... well. , R3 is the nation’s leader in regenerative therapies with over 12,000 successful ...
(Date:11/5/2019)... ... November 05, 2019 , ... Dr. Lauren Kopp ... dentistry to Seattle, WA, including porcelain veneers , smile makeovers, dental implants, ... University of Washington, Dr. Kopp is passionate about serving her Seattle community with ...
Breaking Biology News(10 mins):
(Date:11/5/2019)... ... November 05, 2019 , ... Focal Healthcare ... Mark for its Fusion Bx 2.0 prostate fusion biopsy solution. By combining information ... Bx 2.0 will give urologists across Europe the ability to perform targeted transrectal ...
(Date:11/2/2019)... ... 2019 , ... A clinical trial usually involves many different ... principal investigators, supply chain managers, manufacturers, IRT, CRAs and so on. Lack of ... data, potentially leading to patient risk. , By having a single source of ...
(Date:11/2/2019)... (PRWEB) , ... October 31, 2019 , ... ... released by pharma artificial intelligence pioneer tellic. drug360 brings tellic’s expertise in ... new tool allows researchers to quickly uncover relationships between genes, diseases, variants, phenotypes, ...
(Date:10/30/2019)... ... October 30, 2019 , ... Western University of ... innovation and technology play in educating the next generation of health care providers. ... and presentations by WesternU administrators and representatives of companies working with the University ...
Breaking Biology Technology:
Cached News: