HOME >> BIOLOGY >> NEWS
Northwestern program aims at revealing genetic causes of spina bifida

CHICAGO --- Johnny Doe (not his real name) is a little boy who is helping unravel a mystery for scientists at Northwestern University Medical School and Duke University.

Johnny was born with spina bifida, a common birth defect that deforms the spinal cord and which researchers believe may be linked to mutations in certain genes. Spina bifida affects about four of every 1,000 children born.

To assist in the search for these aberrant genes, Johnny and his parents and families like them contributed DNA samples to the Spina Bifida Genetic Research Project at Northwestern.

Program researchers are analyzing DNA samples from the Does and other families whose children have spina bifida to determine which genetic traits are found more often in these families and how these genes interact with each other and the environment. They also are conducting experiments to identify genes that may increase risk for spina bifida.

Jeffrey S. Nye, M.D., directs the program and is principal investigator on three National Institutes of Health-sponsored studies to determine the genetic basis of spina bifida. Nye, who also has a Ph.D., is an assistant professor of molecular pharmacology and biological chemistry and of pediatrics at the Medical School and at Childrens Memorial Hospital.

Numerous studies have implicated certain drugs, nutritional status (such as folic acid deficiency) and genetic factors in the development of spina bifida, yet scientists are still uncertain as to its actual cause.

Nye, with Northwestern co-investigators David G. McLone, M.D., Joel Charrow, M.D., John F. Sarwark, M.D., and Marcy Speer, Duke University, identified a number of common traits among families who have a child with spina bifida, such as deafness, areas of the hair and skin that lack pigmentation, early graying of the hair and deformities of the face and hands.

"For decades, researchers have known about the increased risk to families for having a second or third
'"/>

Contact: Elizabeth Crown
e-crown@northwestern.edu
312-503-8928
Northwestern University
22-Oct-2000


Page: 1 2

Related biology news :

1. Northwesterns Cancer Genetics Program pinpoints gene that increases cancer risk by 26 percent
2. Northwestern receives $5.65 million for reproductive research
3. New Northwestern center targets brain disorders
4. Northwestern launches major gene banking project
5. A little larceny comes naturally to Northwestern crows
6. Northwestern receives $17 million for functional genomics research
7. Northwestern researchers map gene mutation that makes mice deaf and causes them to dance
8. Northwestern scientists shed new light on neurodegenerative diseases
9. Northwestern researchers clone gene responsible for inner ear motor
10. Northwestern team identifies first enzyme in mammalian circadian clock
11. Northwestern Hosts Public Forum On Future Of Biotechnology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/24/2017)... Jan. 24, 2017 Biopharm Reports has ... laboratory use of nuclear magnetic resonance spectroscopy (NMR). ... and profiled current practices, developments, trends and end-user ... as growth and opportunities. These areas include growth ... instruments, needs and innovation requirements, hyphenated NMR techniques, ...
(Date:1/19/2017)... India , January 19, 2017 According to a ... Opportunities and Forecast, 2014 - 2022," the global biometric sensor market is expected ... 2016 to 2022. In 2015, Asia-Pacific dominated the global ... and private sectors. Continue Reading ... ...
(Date:1/13/2017)... Jan. 13, 2017 Sandata Technologies, LLC, ... the homecare industry, including Electronic Visit Verification™ (EVV™), ... Justin Jugs, as Senior Vice President of Product ... years of homecare experience to Sandata, where he ... plans to align Sandata,s suite of solutions with ...
Breaking Biology News(10 mins):
(Date:2/20/2017)... NEW YORK , Feb. 20, 2017 This ... Thousand by the following Product Types: Xylanase, Amylase, Cellulase, and ... Canada , Japan , ... Latin America , and Rest of World. ... Annual estimates and forecasts are provided for the ...
(Date:2/20/2017)... San Francisco, CA (PRWEB) , ... February 20, ... ... Inspirata®, Inc. announced today the re-launch of “Crosswalk Insight: Oncology™” (Crosswalk), a unique ... enhanced version of Crosswalk can now be accessed through Inspirata’s diagnostic cockpit and ...
(Date:2/20/2017)... ... February 20, 2017 , ... ... radiotherapy patients, prevent chest wall collapses in pre-term infants with respiratory distress, ... a total of $600,000 in funding through the ninth round of the ...
(Date:2/20/2017)...  Former NFL players who had repeated head injuries may ... according to a preliminary study released today that will be ... in Boston , April 22 to 28, ... the muscles and nerves work together, like walking, kicking and ... ...
Breaking Biology Technology:
Cached News: