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Novel approaches to current cellular therapies continue progress toward disease prevention

(San Diego, Calif., December 8, 2003) Over the past few decades, the medical community has made great strides in the search for effective treatments and cures for some of society's most debilitating diseases. One field that has seen a great deal of advancement over the past decade is cellular therapy. Through the use of stem cells, bone marrow transplants, and therapeutic cloning, researchers explore ways to replace diseased or dysfunctional cells with healthy, functioning ones. Although advances in cellular therapy have been limited by complications such as donor availability, immune rejection, and graft versus host disease (GVHD), several studies presented during the 45th Annual Meeting of the American Society of Hematology explore novel approaches that show promise for future medical benefits.

"There are a number of serious diseases about which very little is known," said Janis Abkowitz, M.D., Head of the Hematology Section, University of Washington Medical Center, and Professor of Medicine, University of Washington, Seattle. "Through innovative techniques and continual medical advancements, the scientific community provides us with the hope that we will one day find effective therapies for even the most elusive diseases."

A Bovine Model of Long-Term Hematopoietic Engraftment with Stem Cells Generated by Nuclear Transplantation (Abstract 259)

Therapeutic cloning, also known as somatic cell nuclear transfer, which is used in experimental tissue and organ generation, has recently been explored as a possible treatment for a wide range of degenerative diseases. A study led by Malcom A.S. Moore, D. Phil., Memorial Sloan-Kettering Cancer Center, New York, used the therapeutic cloning technique to examine its potential for hematopoietic stem cell transplantation therapy. Results showed that this technique appears to have the potential to generate cloned, compatible hematopoietic stem cells that are capable o
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Contact: Aimee Frank
amf@spectrumscience.com
202-955-6222
American Society of Hematology
8-Dec-2003


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