HOME >> BIOLOGY >> NEWS
Novel flu vaccine shows promise in mice

PHILADELPHIA - Globally, the influenza virus, or flu, is thought to cause between three and five million cases of severe illness and between 250,000 and 500,000 deaths annually, according to the World Health Organization. New strains of the virus emerge each year, so that the U.S. Centers for Disease Control and other public health services must produce and distribute a new vaccine against the new flu strains each year. And each year, people seeking to avoid a flu infection must arrange to receive a flu shot - rarely a pleasant experience - from their doctor or other health-care provider. Also, the effectiveness of the vaccine is known to decline in the elderly, a population for whom flu infections can be particularly dangerous.

A new prototype vaccine developed by researchers at The Wistar Institute, however, might be able to protect recipients not only against this year's strains of the virus, but also against those yet to come, possibly eliminating the need for an annual shot. In fact, because the vaccine would be administered as a nasal spray, it could eliminate the need for a shot of any kind. A report on the new findings appears in the June 2 issue of the journal Vaccine.

"Current vaccines are quite effective, but they are based on regions of the virus that mutate rapidly, so health officials are constantly faced with the problem of updating the vaccines," says Walter Gerhard, M.D., senior author on the Vaccine report and a professor in the immunology program at The Wistar Institute. "A vaccine directed against a more stable region of the virus would offer important public-health advantages, and this is what we are hoping to be able to develop."

Current flu vaccines trigger an immune response to a pair of prominent viral-coat proteins that mutate constantly, which is the reason last year's flu vaccine is ineffective against this year's flu strains. The experimental vaccine contains an engineered peptide that mimics a third, smaller vira
'"/>

Contact: Franklin Hoke
hoke@wistar.upenn.edu
215-898-3716
The Wistar Institute
27-May-2003


Page: 1 2 3

Related biology news :

1. Novel IBD therapeutic approaches reported from Washington Univ., Barcelona, LSU at APS meeting
2. Novel therapeutic bortezomib moves to phase II trial in lung cancer patients
3. Novel approaches to current cellular therapies continue progress toward disease prevention
4. Novel therapies show promise against myeloid leukemia
5. Novel sensors help clear the air
6. Fox Chase Cancer Center study: Novel DNA-repair gene mutation can cause resistance to cancer drugs
7. Novel proteins designed that block inflammation regulator associated with rheumatoid arthritis
8. Novel therapeutic target identified in fight against Rheumatoid Arthritis
9. Novel bacterium detoxifies chlorinated pollutants
10. Novel gene therapy on the horizon, says Brenner Childrens Hospital pediatrician
11. Novel method identifies hidden genes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/8/2019)... ... 2019 , ... FISO Technologies proudly presents the innovative FOP-M200, ... fiber of 100 microns. With dimensions smaller than any competitive product, FISO is ... leader in the development of fiber optic sensors & signal conditioners used in ...
(Date:5/2/2019)... ... 2019 , ... Philadelphia intellectual property law firm Panitch ... Ph.D., a registered patent agent, has joined the firm as a new member ... technical support and scientific expertise in the pharmaceutical and biotechnical arts and assists ...
(Date:5/2/2019)... ... May 01, 2019 , ... uBiome, the leader in microbial ... Company’s General Counsel, as Interim Chief Executive Officer of uBiome, effective immediately. The ... leave. There will also be an independent investigation into uBiome’s billing practices to ...
Breaking Biology News(10 mins):
(Date:4/18/2019)... ... April 18, 2019 , ... ... team that includes a chemical engineer at Worcester Polytechnic Institute (WPI) has developed ... make it possible to manufacture isobutanol and other biofuels more economically. , Isobutanol, ...
(Date:4/10/2019)... ... April 10, 2019 , ... ... locked into multiple agreements to help companies advance their innovations to clinical ... ranging from synthetic biology companies that are gene editing therapeutic cells for ...
(Date:4/8/2019)... ... April 08, 2019 , ... ... solutions, announced today the launch of their app integration solution, CT Cloud Unite. ... and contact-orientated applications while using CT Cloud Voice and Skype for Business solutions. ...
(Date:3/29/2019)... ... March 28, 2019 , ... Specific ... CARB-X has proceeded with a second stage of funding for Specific’s Reveal™ rapid ... is on top of the $1.7 million already awarded by CARB-X. The additional ...
Breaking Biology Technology:
Cached News: