HOME >> BIOLOGY >> NEWS
OHSU researchers publish final results of groundbreaking smallpox vaccination study

PORTLAND, Ore. Final results of a smallpox vaccine study conducted by researchers at Oregon Health & Science University show America's preparedness for a smallpox outbreak may be greater than initially thought. The research shows 90 percent of those vaccinated 25 to 75 years ago maintain a substantial level of immunity. In addition, researchers concluded that in the long term, repeated vaccinations do not result in a higher level of disease protection. The research project is the largest of its kind ever conducted. The study is printed in the September edition of Nature Medicine.

"Previously, it had been widely accepted that smallpox virus effectiveness lasts only 3 to 5 years," said study principal investigator Mark Slifka, Ph.D., a scientist at the OHSU Vaccine and Gene Therapy Institute. "This research shows that significant immunity levels last for many decades, perhaps throughout a person's entire life. It also shows that repeated vaccinations provide a short-term boost in immunity but, over time, do not create a sustained higher level of protection compared to those persons vaccinated only once."

To conduct the research, OHSU enlisted the help of 332 study participants. Of this larger group, 306 participants had received at least one vaccination within their lifetime, some had undergone as many as 14 inoculations. The timing of vaccinations also varied among study volunteers. Some participants had been vaccinated as recently as one month prior to testing and as long ago as 75 years. The remaining 26 participants in the study had never received a smallpox vaccination in their lifetime and served as control subjects. The study group was very diverse; volunteers included those vaccinated in 43 states and 34 foreign countries.

"Some of our study participants had received repeated vaccinations. In one case, a person who at one time worked in a smallpox hospital had been vaccinated 14 times over their lifetime ," explained Slifka. "While man
'"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
17-Aug-2003


Page: 1 2 3

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. $7.5 Million grant to Yale researchers for role of viruses in cancer
4. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
5. Joslin researchers clarify mechanisms for beta-cell formation
6. Virginia Tech researchers to release findings on Smith River Project
7. Molecular motor myosin VI moves hand over hand, researchers say
8. ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
9. Emory researchers map structure of anti-cancer molecule
10. Leukemia stem cells identified by Stanford researchers
11. EURYI Award given for the first time to 25 young European researchers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2017)... , Jan. 23, 2017  The latest mobile ... smartphone prices have dropped dramatically. The quarterly average price ... 2013 to $276 in Q4 2016.  There are now ... price of $116, up from just 28 a year ... According to Maxine Most , Acuity Market ...
(Date:1/19/2017)... 2017 Sensory Inc ., a ... for consumer electronics, and i nnerCore ... cybersecurity solutions, today announced a global partnership that ... worldwide to bolster security of data sensitive mobile ... authentication platforms they offer, innerCore now offers its ...
(Date:1/13/2017)... Jan. 13, 2017 Sandata Technologies, LLC, ... the homecare industry, including Electronic Visit Verification™ (EVV™), ... Justin Jugs, as Senior Vice President of Product ... years of homecare experience to Sandata, where he ... plans to align Sandata,s suite of solutions with ...
Breaking Biology News(10 mins):
(Date:2/22/2017)... , Feb 22, 2017 ... of the "Global Biological Crop Protection (Bio-Pesticide) Market-By Type, By ... (2016-2021)" report to their offering. ... Global Biological Crop Protection Market is forecasted ... The strong growth in biopesticide or biological crop protection market ...
(Date:2/22/2017)... 2017 Aethlon Medical, Inc. (Nasdaq: ... that validated the ability of the Aethlon Hemopurifier® to ... mortality in immune-suppressed sepsis patients and also contribute to ... objective of the study was to validate the ... (EBV) and Herpes Simplex virus 1 (HSV1) by the ...
(Date:2/22/2017)... ... February 22, 2017 , ... Pharma and biotech ... as European director. Operating from Pennside’s Zurich headquarters, Pennside Partners, GmbH, Mr. Perkins ... Pennside after more than a decade with leading market research firm, GfK. He ...
(Date:2/22/2017)... TRIANGLE PARK, N.C., Feb. 22, 2017  United Therapeutics ... its financial results for the fourth quarter and ... 2016 financial results reflect continued growth as net ... million," said Martine Rothblatt, Ph.D., United Therapeutics, Chairman ... our ability to develop and advance our growing ...
Breaking Biology Technology:
Cached News: