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Ohio State genome map

COLUMBUS, Ohio - A team of Ohio State University genetics researchers have produced a third map of the human genome, this one containing twice the number of genes proposed by two earlier maps and providing annotations that explain the function of all 66,000 genes.

In February, teams of researchers from Celera Genomics, a private biotechnology firm, and counterparts from the Human Genome Project, the federally funded effort to map the genome, published their findings in the prestigious journals Science and Nature respectively. The Ohio State report was published today on the website of the journal Genome Biology.

Both earlier reports proposed that the human genome consists of some 35,000 genes, far less than the estimate of 100,000 to 120,000 genes which researchers had long predicted.

The Ohio State effort, which involved a team of 13 researchers from the university and a bioinformatics company, adds a third major map of the human genome and may accelerate the use of the genome in the diagnosis and understanding of diseases.

"We ended up with a higher estimated number of genes than the other two teams because we compared 13 different gene databases to the DNA sequences in the draft genome produced by the Human Genome Project," said Bo Yuan, head of Ohio State's Div
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Contact: Bo Yuan
Yuan.33@osu.edu
614-292-0656
Ohio State University
3-Jul-2001


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