Ohio researcher receives national award

Pioneered addition of fluoride to toothpaste

M. David Francis of Wyoming, Ohio, will be honored on August 20 by the world's largest scientific society for his pioneering role in developing fluoride additives for toothpaste, bone-strengthening pharmaceuticals and other medical products. He will be designated one of 12 Heroes of Chemistry by the American Chemical Society at its 220th national meeting, in Washington, D.C.

"My original work was in dentistry," said Francis, a physical biochemist who began a career with Proctor & Gamble in 1952. Products based on his findings include two of the most widely used toothpastes: Advanced Formula Crest and Tartar Control Crest.

In nominating him for the award, Joel Shulman, P&G's external affairs manager, wrote: "Dr. Francis' research on the chemistry of tooth enamel structure and formation, and on the mechanism by which the fluoride ion interferes with the destruction of tooth enamel and dentin, played a role in the widespread adoption of fluoride therapies throughout the United States and the world." Shulman noted that cavities among U.S. children have dropped 80 percent since 1967.

"When we found out how [such additives] operated on dental enamel, it was a small jump to see the same thing happen with bone," said Francis. His efforts led to new compounds called bisphosphonates, which treat a variety of bone diseases.

The body constantly recycles its skeletal structure, breaking down old bone tissue and replacing it with new. In disorders like Paget's disease, however, resorption and formation are accelerated, and bones become soft, porous and misshapen.

One of Francis' discoveries, marketed as Didronel, bonds to bone surfaces to slow bone resorption and allow for normal formation. It is approved in 26 countries to help stop age-related bone loss, or osteoporosis. A related product, Osteoscan, is used to delineate patients' bone structure. The bisphosphonate molecule carries a ra

Contact: Christina Curtin
American Chemical Society

Page: 1 2

Related biology news :

1. Belgian researchers explore revolutionary approach to angiogenesis
2. Award winning researchers reveal potential new role for Glivec
3. University of Alberta researcher looks for clues to mysterious disease
4. $7.5 Million grant to Yale researchers for role of viruses in cancer
5. New anti-inflammatory strategy for cancer therapy identified by UCSD researchers
6. Joslin researchers clarify mechanisms for beta-cell formation
7. Pioneering AIDS researcher to speak at UH
8. Defensive action by influenza viruses demonstrated by Hebrew university researcher
9. Virginia Tech researchers to release findings on Smith River Project
10. Molecular motor myosin VI moves hand over hand, researchers say
11. Tiny molecules have big potential as cancer drugs, Stanford researcher believes

Post Your Comments:

(Date:11/16/2015)... Calif. , Nov 16, 2015  Synaptics ... of human interface solutions, today announced expansion of ... TouchView ™ touch controller and display driver ... revolution of smartphones. These new TDDI products add ... TD4100 (HD resolution), TD4302 (WQHD resolution), and TD4322 ...
(Date:11/10/2015)... , Nov. 10, 2015  In this ... the basis of product, type, application, disease ... in this report are consumables, services, software. ... are safety biomarkers, efficacy biomarkers, and validation ... report are diagnostics development, drug discovery and ...
(Date:11/2/2015)... , Nov. 2, 2015  SRI International has ... to provide preclinical development services to the National Cancer ... SRI will provide scientific expertise, modern testing and support ... of preclinical pharmacology and toxicology studies to evaluate potential ... --> The PREVENT Cancer Drug Development Program is ...
Breaking Biology News(10 mins):
(Date:11/27/2015)... 2015 --> ... companion diagnostics is one of the major ... pharmaceutical companies and diagnostic manufacturers working together ... http://www.rnrmarketresearch.com/global-cancer-biomarkers-market-2015-2019-market-report.html . --> http://www.rnrmarketresearch.com/global-cancer-biomarkers-market-2015-2019-market-report.html ... global cancer biomarkers market spread across 89 ...
(Date:11/25/2015)...  PharmAthene, Inc. (NYSE MKT: PIP) announced  today that ... plan (Rights Plan) in an effort to preserve the ... Section 382 of the Internal Revenue Code (Code). ... of its NOLs could be substantially limited if the ... 382 of the Code. In general, an ownership change ...
(Date:11/25/2015)... Nov. 25, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... President and CEO of Neurocrine Biosciences, will be presenting ... New York . http://www.neurocrine.com ... website approximately 5 minutes prior to the presentation to ... the presentation will be available on the website approximately ...
(Date:11/25/2015)... November 25, 2015 The ... is a professional and in-depth study on the ...      (Logo: http://photos.prnewswire.com/prnh/20141014/710132 ) , ... industry including definitions, classifications, applications and industry chain ... the international markets including development trends, competitive landscape ...
Breaking Biology Technology:
Cached News: