HOME >> BIOLOGY >> NEWS
Oral exposure to anti-oxidant glutathione could help prevent flu infections

Emory University scientists reported today at the Experimental Biology 2000 meeting in San Diego that glutathione, a naturally occurring anti-oxidant compound, could help prevent infection by the influenza virus if administered directly to the tissues lining the mouth and upper airway. The scientists suggested that glutathione concentrated in a lozenge or spray might be the most effective way to use the compound as a flu preventive.

Glutathione, which occurs naturally in a variety of foods, has been shown in research studies to reduce cellular damage by reactive oxygen from a variety of cancer causing agents, including ionizing radiation and environmental carcinogens. Studies by Dr. Jones and his colleagues on the potential role of dietary glutathione, however, have previously found that the body does not appear to use the compound on a systemic basis to ward off disease.

While studying the role of glutathione as an anti-cancer agent, the Emory scientists discovered that one of the enzymes that uses glutathione to detoxify cancer-causing chemicals and oxidants is deposited in the mucous layer lining the mouth and nose, thus providing an extracellular barrier to toxic chemicals. This led them to consider a possible role for glutathione as an anti-flu protectant.

The flu virus is normally released from infected cells as an inactive particle. To infect another cell, it must be activated by having one of its proteins cleaved (split into two pieces) by a protease enzyme. Proteases, along with proteins that normally inhibit their activation, are present in the fluid that lines the epithelial cells (the cells that line the mouth, upper airways and intestine). Scientists have found through studies in mice that viral infections result in oxidative responses that inactivate natural protease inhibitors, thus enhancing viral activation. They also have found that activation of the virus particles could be controlled by oxidation reducti
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Apr-2000


Page: 1 2

Related biology news :

1. USC study links historical increases in life span to lower childhood exposure to infection
2. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
3. Managing occupational exposures to potential bioterrorist agents
4. Infant rats eagerly accept high concentrations of alcohol upon first exposure
5. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
6. Transplant rejection averted by simple light exposure in Stanford animal study
7. OHSU researchers discover possible connection between infant hormone exposure, obesity
8. Prenatal exposure to second-handsmoke greater for disadvantaged children, study finds
9. Deficits associated with prenatal alcohol exposure can be seen as early as infancy
10. Household activities release a cloud of dust, increasing exposure to particulate pollution
11. Models help estimate childrens exposure to toxins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2018)... SAN DIEGO (PRWEB) , ... December 04, 2018 ... ... to leverage Fastec’s extensive expertise and existing IP in the development of innovative ... technology has been integrated into diverse systems from microfluidics to industrial machinery and ...
(Date:11/29/2018)... , ... November 29, 2018 , ... ... Semba Biosciences with the intention of acquiring full ownership. The transaction was approved ... was executed on November 14, 2018. “We are extremely pleased to team up ...
(Date:11/27/2018)... (PRWEB) , ... November 26, 2018 , ... ... Dr. Brandon Wuerth, MD, Founder of the website IBDwatch and Gastroenterology Fellow at ... leading scientists and doctors from around the world, Dr. Wuerth will bring to ...
Breaking Biology News(10 mins):
(Date:11/20/2018)... ... November 19, 2018 , ... The International Society ... the Chinese translation of Best Practices: Recommendations for Repositories, Fourth Edition. , The ... at advancing the science of biobanking to meet the needs of a growing ...
(Date:11/20/2018)... ... ... Each year Forbes receives thousands of nominations for candidates wishing to be selected for ... years of age. The Forbes 30 Under 30 list showcases the top 30 individuals ... Science. , In 2017, Visikol CEO Dr. Michael Johnson was named to the ...
(Date:11/15/2018)... ... 14, 2018 , ... Hüpnos announces the launch ... public. It is estimated that 90 million Americans suffer from persistent ... The resulting daytime fatigue causes extreme difficulty with concentration, focus and memory. ...
(Date:11/13/2018)... SAN DIEGO (PRWEB) , ... November 12, 2018 ... ... medical device to reduce stethoscope contamination that two large U.S. studies, published last ... appearing in the American Journal of Infection Control (AJIC) conclude that stethoscopes are ...
Breaking Biology Technology:
Cached News: