HOME >> BIOLOGY >> NEWS
Oral exposure to anti-oxidant glutathione could help prevent flu infections

Emory University scientists reported today at the Experimental Biology 2000 meeting in San Diego that glutathione, a naturally occurring anti-oxidant compound, could help prevent infection by the influenza virus if administered directly to the tissues lining the mouth and upper airway. The scientists suggested that glutathione concentrated in a lozenge or spray might be the most effective way to use the compound as a flu preventive.

Glutathione, which occurs naturally in a variety of foods, has been shown in research studies to reduce cellular damage by reactive oxygen from a variety of cancer causing agents, including ionizing radiation and environmental carcinogens. Studies by Dr. Jones and his colleagues on the potential role of dietary glutathione, however, have previously found that the body does not appear to use the compound on a systemic basis to ward off disease.

While studying the role of glutathione as an anti-cancer agent, the Emory scientists discovered that one of the enzymes that uses glutathione to detoxify cancer-causing chemicals and oxidants is deposited in the mucous layer lining the mouth and nose, thus providing an extracellular barrier to toxic chemicals. This led them to consider a possible role for glutathione as an anti-flu protectant.

The flu virus is normally released from infected cells as an inactive particle. To infect another cell, it must be activated by having one of its proteins cleaved (split into two pieces) by a protease enzyme. Proteases, along with proteins that normally inhibit their activation, are present in the fluid that lines the epithelial cells (the cells that line the mouth, upper airways and intestine). Scientists have found through studies in mice that viral infections result in oxidative responses that inactivate natural protease inhibitors, thus enhancing viral activation. They also have found that activation of the virus particles could be controlled by oxidation reducti
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
16-Apr-2000


Page: 1 2

Related biology news :

1. USC study links historical increases in life span to lower childhood exposure to infection
2. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
3. Managing occupational exposures to potential bioterrorist agents
4. Infant rats eagerly accept high concentrations of alcohol upon first exposure
5. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
6. Transplant rejection averted by simple light exposure in Stanford animal study
7. OHSU researchers discover possible connection between infant hormone exposure, obesity
8. Prenatal exposure to second-handsmoke greater for disadvantaged children, study finds
9. Deficits associated with prenatal alcohol exposure can be seen as early as infancy
10. Household activities release a cloud of dust, increasing exposure to particulate pollution
11. Models help estimate childrens exposure to toxins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... NEW YORK , March 30, 2017 ... by type (physiological and behavioral), by technology (fingerprint, AFIS, ... recognition, voice recognition, and others), by end use industry ... travel and immigration, financial and banking, and others), and ... Europe , Asia Pacific ...
(Date:3/28/2017)... -- The report "Video Surveillance Market by ... Devices), Software (Video Analytics, VMS), and Service (VSaaS, Installation ... 2022", published by MarketsandMarkets, the market was valued at ... reach USD 75.64 Billion by 2022, at a CAGR ... considered for the study is 2016 and the forecast ...
(Date:3/24/2017)... MILAN , March 24, 2017 The Controller ... Deputy Controller Mr. Abdulla Algeen have received the prestigious international ... Continue Reading ... ... small picture) and Deputy Controller Abdulla Algeen (small picture on the right) ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... , ... AMRI, a global contract research, development and manufacturing ... and quality of life, will now be offering its impurity solutions as a ... requirements for all new drug products, including the finalization of ICH M7 earlier ...
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its ... 2018 in San Francisco, CA. The Summit brings together current and former FDA office ... directors and government officials from around the world to address key issues in device ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study ... in frozen and fresh in vitro fertilization (IVF) transfer cycles. The ... IVF success. , After comparing the results from the fresh and frozen transfer ...
(Date:10/10/2017)... ... 2017 , ... Dr. Bob Harman, founder and CEO of VetStem Biopharma, ... The event entitled “Stem Cells and Their Regenerative Powers,” was held on ... DVM, MPVM was joined by two human doctors: Peter B. Hanson, M.D., Chief of ...
Breaking Biology Technology:
Cached News: